This report presents the case of severe tooth wear and vertical dimension loss in a 71-year-old male patient. A combined conventional and digital approach was employed for full-mouth rehabilitation. After determining an increase in the vertical dimension of 5.5 mm using an anterior jig and diagnostic wax-up, provisional restorations were fabricated and adjusted throughout the adaptation period.For the fabrication of the final prosthesis, digital methodologies such as oral scanning and occlusal acquisition were performed. To obtain precise margin data, a die model was fabricated using the traditional impression method, followed by model scanning, which was then combined with intraoral scan data. The final prosthesis was made of zirconia to enhance esthetics and strength. Consequently, the treatment enhanced both function and esthetics, leading to high patient satisfaction with the outcomes.

This study evaluated the long-term stability and efficacy of occlusion achieved by setting a normalized chewing position as the therapeutic position in patients with abnormal chewing positions due to tooth loss or malocclusion. Furthermore, the study monitored the recovery rate of the stomatognathic system. Sixteen patients undergoing oral functional rehabilitation participated in the study, utilizing an intraoral Gothic arch tracer to normalize abnormal chewing positions and designate the apex of the resultant chewing patterns as the therapeutic position. The first set of data was gathered during occlusal reconstruction at the point when a therapeutic position was necessary, and the second set was collected approximately 10 years later under the same conditions. Four mandibular movements—chewing movements for hard food (CM-H), chewing movements for soft food (CM-S), border movement (BM), and maximum intercuspation position (MICP)—were compared to assess the long-term stability between the chewing position and occlusion and the recovery rate of the stomatognathic system. The findings showed a 63% concordance between CM-H and MICP, confirming the long-term stability of both the chewing position and occlusion. Furthermore, the concordance between CM-H and CM-S increased by 13%, whereas the alignment between the chewing position and BM increased by 25%. In summary, the concordance across all four movements improved by 19%, demonstrating increased long-term recovery rate of the stomatognathic system. These findings provide clinical evidence that occlusal reconstruction centered on the chewing position offers long-term stability and recovery. By establishing an efficient occlusion that harmonized with the chewing patterns, this approach compensates for age-related declines in chewing function and helps maintain the stomatognathic system health.

The present narrative review thoroughly investigates recent publications on custom surgical guides for orthognathic surgery, focusing on the evaluating their advancements, efficacy, and precision, particularly in terms of enhancing the surgical outcomes. Key areas, such as technical limitations, patient-specific challenges, and cost and accessibility issues, are explored. A significant finding is the scarcity of studies employing robust statistical methods, making many conclusions preliminary and underscoring the need for more rigorous research studies. Future studies should aim to provide a comprehensive, statistically validated assessment of the role and impact of custom surgical guides in orthognathic surgery. While this review highlights their potential, it also identifies critical gaps in the existing literature.

A glandular odontogenic cyst (GOC) is a rare type of odontogenic cyst characterized by a broad clinical and pathological spectrum, overlapping with different lesions ranging from lateral periodontal cysts to low-grade mucoepidermoid carcinoma. Further, including GOC in the initial diagnosis is frequently challenging due to its nonspecific radiological results. Despite its rarity, accurate GOC diagnosis is crucial due to its aggressive nature and high recurrence potential. Therefore, various GOC cases need to be presented to clinicians. This study aims to report the clinical and radiological characteristics of two cases of GOCs that were initially misdiagnosed as radicular cysts.

Vertical positioning of dental implants relative to the cementoenamel junction (CEJ) of the adjacent teeth is essential for maintaining peri-implant bone stability and long-term success. This retrospective study evaluated how the vertical distance from the CEJ affects peri-implant bone loss in patients who had implants positioned at various distances from the CEJ. Bone loss was evaluated using panoramic radiographs over a 2-year follow-up period, with additional consideration of factors such as smoking and diabetes. Implants positioned >4 mm away from the CEJ exhibited a higher mean bone loss; however, this difference was not significant. Smoking significantly influenced bone loss, whereas diabetes and jaw location had no significant effect. These results highlight the potential influence of vertical implant positioning on peri-implant bone health and highlight the importance of appropriate maintenance care to reduce bone loss and ensure long-term implant survival.

Achieving periodontal regeneration in class III furcation defects is challenging. Many studies have applied growth factors to periodontal defects, including fibroblast growth factors (FGFs), which demonstrate angiogenic activity and mitogenic ability. This study aimed to evaluate periodontal regeneration following the application of FGF-2 to deproteinized bovine bone mineral (DBBM) in surgically created supra-alveolar class III furcation defects of the mandibular premolars of beagles. The defects were divided into the control, DBBM, and FGF/DBBM groups. For the control group, only root planing was performed. For the DBBM group, only DBBM particles were implanted into the furcation. For the FGF/DBBM group, DBBM was soaked with 0.3% FGF-2 solution, and FGF-2/ DBBM was then positioned into the furcation. After 8 weeks, the dogs were euthanized. The micro-computed tomography analysis revealed that the changes in the bone volume of the furcation area were significantly greater in the FGF/DBBM group than in the DBBM group. In the histomorphometric analysis, the area of the newly formed bone was significantly greater in the FGF/DBBM group than in the DBBM or control group. The cementum extension was significantly longer in the FGF/DBBM or DBBM group than in the control group. The epithelial area was significantly less in the FGF/DBBM group than in the DBBM or control group. The application of FGF combined with DBBM to a class III defect enhanced the regeneration of periodontal tissues and increased the healing rate. This finding indicates that FGF-2 combined with DBBM can be applied to class III defects clinically.

Porphyromonas gingivalis is a key pathogen in periodontitis associated with Alzheimer’s disease (AD) through multiple mechanisms.Recent findings regarding the existence of its DNA and proteins in AD’s brain tissues reveal its ability to breach the blood–brain barrier (BBB). This study overviews the potential mechanisms of action of P. gingivalis, including its direct migration to the brain via BBB disruption and indirect effects mediated by outer membrane vesicles carrying toxic components, such as gingipains, lipopolysaccharides, and fimbriae. The implications of P. gingivalis-induced neuroinflammation, amyloid-β aggregation, and tubulinassociated unit protein modification in AD pathology, together with emerging therapeutic strategies targeting gingipain, were also explored.

Unicystic ameloblastoma is generally less aggressive and has a lower recurrence rate than solid or multicystic ameloblastomas, making it more amenable for conservative treatments such as enucleation or curettage. However, in case of large cysts, accurate diagnosis can be challenging depending on the location of biopsy. If unicystic ameloblastoma is misdiagnosed as other odontogenic or inflammatory cysts, the risk of postoperative recurrence increases. In this paper, we report a case of early recurrence following decompression and enucleation of a large maxillary unicystic ameloblastoma.

Facial burns in infant can disrupt maxillofacial growth, leading to deformities and functional impairments. These burns, often occurring in children aged 8–13 months, may result in malocclusion and facial asymmetry caused by altered neuromuscular development. The historical principles of maxillofacial burn management have been established by pioneers such as Kazanjian and Hyslop. In 1849, Simon P. Hullihen performed the first documented orthognathic surgery for a burn-induced deformity on a young patient with mandibular prognathism. In the present study we discuss a similar case involving a 10-year follow-up, demonstrating the use of virtual surgical simulation in evaluating and treating maxillofacial deformities resulting from electrical burns in children.