Background: In the treatment of plaque-induced gingivitis, in addition to mechanical plaque control, the use of chemical plaque control such as mouth rinses for a certain period has shown a positive effect on treatment outcomes and prognosis. Aim: To evaluate the efficacy of a probiotic mouthwash in the treatment of plaque-induced gingivitis. Materials and Methods: A randomized controlled clinical trial was designed for a period of 2 weeks on 45 systemically healthy subjects between 20 and 25 years having plaque-induced gingivitis. The study population was divided into three groups. Group 1-15 subjects were advised experimental (probiotic) mouthwash. Group 2-15 subjects were advised positive control (chlorhexidine) mouthwash and Group 3-15 subjects into a negative control group. Oral prophylaxis was done for all groups at baseline. After the proper oral hygiene instructions, groups 1 and 2 were instructed to rinse their mouth with 15 ml of their respective mouthwashes, for 1 min twice daily, 30 min after brushing. Clinical parameters such as Full mouth plaque score (FMPS), Full mouth bleeding score (FMBS) were assessed at baseline, 2 weeks respectively. Results: At baseline, there was no statistically significant difference between the groups in terms of FMBS and FMPS mean values (p=0.174, p=0.887). At day 14, the FMPS, FMBS mean values were significantly reduced by all treatment modalities ranking probiotic and chlorhexidine is greater than negative control group (p<0.001, p<0.001). Conclusion The probiotic mouthwash was effectively used as an adjunct to mechanical plaque control in the treatment of plaque-induced gingivitis.

Background: Demyelinating disorders are a group of chronic immune-mediated diseases affecting myelinated axons in the central nervous system, which lead to life-long disability. In Mongolia, the last regional prevalence study was conducted in 2010. Our study objective is to describe the current prevalence of multiple sclerosis (MS) and other demyelinating disorders in Mongolia. : Aim Materials and Methods: We registered MS, neuromyelitis optica spectrum disease (NMOSD), myelin oligodendrocyte glycoprotein (MOG), and acute disseminated encephalomyelitis (ADEM) cases diagnosed according to the 2017 McDonald criteria, the 2023 NMOSD diagnostic criteria, International MOGAD Panel proposed criteria. Results: The study was conducted in all tertiary, 7 regional, and 20 provincial hospitals across Mongolia and has collected comprehensive data on 965 patients. The prevalence of total demyelinating disorders was estimated to be 27.2, MS 15.6, NMOSD 5.6, MOG 0.06, and ADEM 0.9 per 100,000 total population, respectively. The prevalence of demyelinating disorders between provinces was compared in order of geographical latitude, from lowest to highest, and was statistically significant. Latitude is associated strongly with the prevalence of demyelinating disorders (p=0.006, 95% CI 14.3-22.4, Pearson correlation=0.603) and moderately with the prevalence of MS (p=0.028, 95% CI 9.39-15.6, Pearson correla tion=0.503). Conclusion In Mongolia, the prevalence of MS has significantly increased and can be considered at medium risk, but still much lower than that in Western countries. The prevalence of NMOSD is almost similar to other Asian countries. An obvious latitude gradient for demyelinating disorders was observed in the Mongolian population.

Background: The main risk factors for childhood overweight and obesity include the consumption of sugar-sweetened beverages and other sweetened foods. The sugar content of sugar-sweetened beverages was different from the nutritional information on the packaging. Aim: To determine sugar and brix content in domestic manufactured sugar-sweetened beverages, and compare information on the packaging and regulatory standards. Materials and Methods: The sugar and brix content in sugar-sweetened beverages was determined by laboratory anal ysis, including 150 domestically manufactured sugar-sweetened beverages. Laboratory analysis carried out in the Chemical toxicology laboratory of the National Reference Laboratory for Food Safety, MASM, determined sugar using a saccharometer and brix using refractometry. : Results: The study included 150 Mongolian sugar-sweetened beverages, including 20.7% (n=31) carbonated drinks, 47.3% (n=71) fruit drinks, 16.0% (n=24) tea drinks, 1.3% (n=2) energy drinks, 14.7% (n=22) flavored water. Sugar content 0.0–15.6% in sugar-sweetened beverages. The laboratory analysis results compared with information on the packaging 72.0% (n=108) difference between 0.1–11.3%, 10.7% (n=16) same, do not have sugar content in the nutritional information on the packaging 17.3% (n=26). Brix contained 0.2–13.0% carbonated drinks, 4.9–15.7% fruit drinks, 0.6–9.8% tea drinks, 7.7–16.0% energy drinks, and 0.1–9.7% flavored water. Conclusions 1. Sugar content 0.0–15.6%, brix 0.0–16.0% in Mongolian sugar-sweetened beverages. 2. The laboratory analysis results compared with nutritional information on the packaging 72.0% (n=108) difference between 0.1–11.3%, 10.7% (n=16) same nutritional information on the packaging, do not have sugar content in the nutritional information on the packaging 17.3% (n=26). 3. 37.3% of Mongolian sugar-sweetened beverages are unsatisfied with regulatory standards.

The study is devoted to the morphological characteristics of the maturation of lung tissue structures in the fetal period. Fetal histology of the lungs presents the intrauterine development of lung tissue in four successive stages: pseudoglandular, canalicular, saccular and alveolar, each has specific morphological criteria. The following morphological features are predetermined: the development of alveolar epithelium, the ratio of mesenchyme towards the area in alveolar spaces, the degree of proliferation and location of vessels of the microcirculatory bed towards prealveolar partitions. During the fetal period the alveolar columnar epithelium is flattened and differentiates into alveolocytes type I lung histology with the demonstration of histological preparations of the lungs at different stages of intrauterine development. Keywords: fetal lungs, prealveolar structures, pseudoglandular stage, canalicular stage, alveolar stage, alveolar capillary membrane, immunohistochemical study. 16 and II, the area of the mesenchyme gradually decreases and by the birth of a full-term newborn kid it is present mainly in the thickness between the alveolar septa, microcirculation vessels, initially laying deep in the thickness of the mesenchymal tissue, gradually proliferate, approach the pre-alveolar epithelium, channeling it with the formation of alveolar capillary membranes. Air exchange in the lung tissue is mainly provided with two factors: the presence of second-order alveolocytes capable of producing surfactant, and a sufficient formation of alveolias well. This work summarizes the basics of fetal lung histology with the demonstration of histological preparations of the lungs at different stages of intrauterine development.

Backgroun: Air pollution is a major global public health concern that poses serious risks to human health regardless of a country’s level of economic or technological development. According to the World Health Organization (WHO, 2021), nine out of ten people worldwide breathe polluted air, and air pollution is responsible for the deaths of approximately 800 people every hour and 13 people every minute. Prolonged exposure to polluted air has been linked to a wide range of chronic illnesses, including chronic obstructive pulmonary disease (COPD), lung and bronchial cancers, asthma, and stroke. In Mongolia, air pollution reaches its highest levels during the winter months, particularly in Ulaanbaatar, where the majority of the country’s population resides. A study conducted by Enkhjargal G. (2012) reported that the concentrations of PM10 and PM2.5 in Ulaanbaatar were 7–8 times higher than the WHO recommended guidelines. In response to such challenges, many countries have increasingly adopted low-cost, direct measurement devices such as PurpleAir to monitor air quality. These devices are valued for their accessibility, network connectivity, and potential role in smart city pollution management systems. Despite their global application, there remains a lack of research in Mongolia on the use of PurpleAir sensors to measure PM2.5 concentrations and compare the results with official monitoring station data. Addressing this gap is essential for improving local air quality monitoring capacity and informing effective public health and environmental policies. Aim: Determination of PM2.5 particulate matter pollution in the outdoor environment of Ulaanbaatar city using a direct measurement device (Purple Air). Materials and Methods: A cross-sectional study design was employed. Direct measurement devices (Purple Air) were installed in selected districts of central Ulaanbaatar between December 2024 and February 2025, measuring PM2.5 concentrations at two-minute intervals over 24-hour periods. All data were statistically processed and analyzed using the SPSS-26 software package. Results: The average concentration of PM2.5 particles in the air of Ulaanbaatar city in winter is 66.68 μg/m3. Compared to the districts, the highest concentration was determined in SKHD (118.58±90.22 μg/m3), while the lowest concentration was determined in KHUD (42.37±43.51 μg/m3). Compared to the days of the week, the highest concentrations were measured on Monday (76.68±71.98 μg/m³), Saturday (77.50±71.63 μg/m³), and Sunday (80.34±74.45 μg/m³). The highest concentration of PM2.5 particles occurred from 6 pm to 1 am, and the lowest concentration was measured during the day (between 2 pm and 4 pm). The highest concentration of PM2.5 was measured in December (74.22±73.45 μg/m3), while the lowest concentration was measured in February (50.25±57.44 μg/m3). Conclusion The concentration of PM2.5 in the air of Ulaanbaatar city is 1.7 times higher than the general standard and technical requirements of Mongolia in winter, and the highest concentration is in the SKHD. The highest concentration of PM2.5 occurs more often in December and at night than in the winter months.

Introduction: Total environment 24 % of all estimated global deaths are linked to the environment. As of 2022, Ulaanbaatar has a population of 1,691,800, vehicles 435,725, thermal power plants 4, market and shopping centers 111, factories 13,465, and 225 gas stations. Also, 1.5 million tons of waste are generated annually, 1135.6 tons of coal are used, and environmental pollution is increasing year by year. Therefore, it is necessary to investigate the heavy metal contamination of the soil of Ulaanbaatar city and protect the health of the population. Purpose: To determine heavy metals pollution in the soil of Ulaanbaatar city Materials and Methods: We used descriptive research design in this study. Secondary data from Meteorological and Environmental Monitoring Department was used. The content of heavy metals such as lead (Pb), mercury (Hg), chromium (Cr), and cadmium (Cd)) in the soil was evaluated in comparison with the maximum permissible amount specified in the MNS 5850:2019 standard. Statistical analyzing was calculated using SPSS-25 software, and p<0.05 was considered statistically significant. Results: The average concentration of heavy metals in the soil of residential areas of 9 districts of Ulaanbaatar city is cadmium 0.43 mg/kg (min=0, max=26.6), mercury 0.22 mg/kg (min=0, max=4), chromium 11.2 mg/kg ( min=0, max=1609.6), lead is 24.4 mg/kg (min=0, max=257.2). Cadmium concentration in soil Bagakhangai (25%), Baganuur (19.7%), Khan-Uul (18.9%), lead concentration in Nalaikh (8.3%), Bayanzurkh (5.4%), Chingeltei (3.3), mercury concentration in Baganuur ( 24.7%), Khan-Uul (18.4%), and chromium concentration in certain locations of Khan-Uul (4.7%) districts exceeded the standards, respectively. The concentration of soil cadmium (21.2%) and lead (7.7%) near the technical market, mercury concentration (26.3%) near the market and shopping center, and chromium concentration (58.9%) near the central treatment plant exceeded the maximum permissible levels. Conclusion Cadmium and mercury pollution were mainly detected in the heavy metal pollution of the soil of Ulaanbaatar city, and there is heavy metal pollution in certain locations of Baganuur and Khan-Uul districts. Heavy metal pollution is caused by activities such as technical markets, auto repair shops, markets, shopping centers, and treatment plants.

Radon is a radioactive gas that has no smell, colour or taste. Radon is produced from the natural radioactive decay of uranium, which is found in all rocks and soils. Radon can also be found in water. Outdoors, radon quickly dilutes to very low concentrations and is generally not a problem. The average outdoor radon level varies from 5 Bq/m³ to 15 Bq/m³. However, radon concentrations are higher indoors and in areas with minimal ventilation, with highest levels found in places like mines, caves and water treatment facilities. In buildings such as homes, schools, offices, radon levels can vary substantially from 10 Bq/m³ to more than 10 000 Bq/m³.
The effects of residential radon on human health have been studied worldwide since the 1980s. In addition, studies conducted in Europe, North America, and China have proven that even radon levels in dwellings below the acceptable level can pose long-term risks to residents health and contribute to the development of lung cancer. Relying upon the average level of radon and the prevalence of cigarette smoking in the country, radon causes 3-14% of the total incidence of lung cancer. An increase of 100 Bq/m 3 in long time average radon concentration increases the risk of lung cancer by approximately 16%, which is considered that there is a linear relationship between radon concentration and lung cancer.

Healthcare is a rapidly growing industry as medical treatments become more sophisticated, more in demand due to increasing incidence of chronic disease and more widely available worldwide. As the amount of healthcare waste continues to increase, there is a need for further research in the field to meet the global demand for proper disposal of healthcare waste. The growing healthcare consumption, driven by various factors, is contributing to the rise in hospital waste, which in turn is putting pressure on current waste management systems.Currently, healthcare institutions manage waste by segregating at the source, safely transporting infectious waste, and disposing of it through incineration, autoclaving, or landfill methods. Both incineration and autoclaving processes have negative environmental and human health impacts. To reduce the amount of healthcare waste generated, it is necessary to train healthcare workers to properly segregate waste according to its type, following established standards.
Governments can take action to improve waste disposal practices, reduce the generation of infectious waste, and ensure that all types of healthcare waste are properly disposed of. This can include:
• Governments should have clear and standardized definitions for both infectious and non infectious healthcare waste, and enhance the regulatory and legal framework to prevent illegal disposal of waste.
• Healthcare institutions should be provided with incentives, financial support, and other measures to reduce hospital waste, with a particular focus on reducing infectious waste in local health institutions.
• Governments should provide research grants to support studies aimed at reducing and managing healthcare waste disposal effectively.
These measures would help improve the overall management and reduction of healthcare waste and ensure a safer and more sustainable approach to waste disposal.

Introduction: Colorectal cancer remains one of the critical healthcare challenges nowadays. There are a lot of studies done on colonic polypectomy around the world, and mostly diagnosis with dysplasia change, so we consider to chose to study this topic. Aim: In this study, we aimed to compare the between cold snare polypectomy (CSP) and hot snare polypectomy (HSP) of removing colon polyps. This method helped us to investigate which of the two methods is most prevalent for polypectomy. Materials and Method: The research was carried out using a targeted sampling method from the cases where colonoscopy was performed between 2022 and 2023, based on the Center for Imaging Diagnostics and Pathology of Third General Hospital of Mongolia with a colon polyps less than 5mm in size should be removed using the cold snare method according to the recommendation, and polyps between 5-10 mm should be removed using the hot snare method. After polypectomy, we assessed deep mucosal lesions using the Sydney classification. Result: The average age of the 81 cases included in the study was 57.9 years, and the male-female ratio was 1:1.2.149 cases (75.6%) of slightly elevated type 0-IIa according to the Paris classification, according to the morphological structure revealed by endoscopy, while 79 cases (75.6%) were tubular adenoma according to histological analysis. (38.9%), low grade dysplasia 52 (25.6%) and high grade dysplasia 3 (1.5%) cases are noteworthy. Average polyp was 5-9 mm. Most of polyps removed was left side of colon especially in sigmoid colon. Bleeding rate was higher in hot snare method 11.5%. (1/149, 0.7%, 5/52, 9.6%; P = 0.6). There was no recurrent rate and no perforation in our study. Conclusions In our study, average size of 5-9 mm were removed and slightly elevated (0-IIa), sessile (0-Is) type of polyps were commonly found in the sigmoid colon. There is a higher risk of bleeding due to mucosal damage in hot snare polypectomy. A combination of hot and cold methods is equally effective for resection of colon pollyps up to 1 cm in size.

Introduction: On January 31, 2020, the World Health Organization (WHO) declared the infection with coronavirus (COVID-19) an “International Public Health Emergency” and on March 11, 2020, declared it a “Pandemic”. To date, the statistics of the total number of cases of COVID-19 infection is more than 676 million, and the number of deaths is more than 6.8 million. Therefore, reducing the mortality and spread of infection is an urgent issue for the world community. In March 2020, Mongolia confirms its first new case of COVID-19 imported by air transport from abroad. Since then, there have been over 1 million total cases of infection and 2,136 deaths. The aim of this study is to determine some outcomes related to the COVID-19 pandemic in Mongolia. Materials and Methods: We used descriptive research design in this study. Quantitative secondary data about causes of total mortality, COVID-19 cases during the pandemic were analysed from Health Development Center. Also, we conducted cross sectional study on concepts of long COVID-19 condition among 188 people who were recovered from their COVID-19 illness. The SPSS-23 software was used to analyze the data. Results: The mortality rate of the total population of Mongolia in 2021 was compared to this indicator for 2010, 2015, and 2020 and its growth rate was calculated. When calculating the mortality rate of the total population of Mongolia, the number of deaths per 10,000 population in 2021 was 47.4, which is an increase of 11% compared to 2020 in terms of growth rate. As for the causes of mortality growth, cardiovascular deaths increased by 16.7%, deaths of injuries and accidents by 8.2%, and deaths of respiratory diseases increased by 61.1% respectively. There was a positive medium correlation (p=0.007) between the number of cases of COVID-19 infection and the population total mortality.
A total of 188 people were included in the study, with a mean age of 38±12.3 years (minimum=18, maximum=70). Females were 51.1% (96), males were 48.9% (92), males were 6.9% (6.9%), and females were 13.3%. Long COVID-19 condition was found in 20.2% of the respondents. The duration of symptoms after infection with COVID-19 was (23.6%) 3 months, (21%) 1 year, and (23.6) still had symptoms. Symptoms such as fatigue, insomnia, cognitive decline (42.1%), shortness of breath (36.8%), cough, and heartburn appeared. Conclusions
1. During the COVID-19 pandemic in Mongolia, the total mortality of the population has increased, including pneumonia and heart attack. Total mortality of the population during the pandemic depended on the number of cases of COVID-19.
2. About one in five people with COVID-19 answered that observed long-term symptoms of COVID-19, such as fatigue, insomnia, shortness of breath, and cognitive changes, which were more common in women and people with chronic conditions.