1.Rare arterial variations associated with dorsal pancreatic agenesis
George TRIANTAFYLLOU ; Panagiotis KOKOROPOULOS ; Spyridon CHRISTODOULOU ; Orestis LYROS ; Nikolaos OIKONOPOULOS ; Nikolaos ARKADOPOULOS ; Maria PIAGKOU
Anatomy & Cell Biology 2026;59(1):188-192
The purpose of the current case is to describe a very rare coexistence of a replaced common hepatic artery (rCHA) and dorsal pancreatic agenesis with notable surgical implications. Preoperative computed tomography angiography, magnetic resonance imaging, and magnetic resonance cholangiopancreatography were performed in a 53-year-old female with cholangiocarcinoma. Imaging revealed an rCHA arising from the superior mesenteric artery (SMA) and coursing anterior to the pancreatic head, supplying the right and left hepatic arteries, right gastroepiploic artery, and both the superior and inferior pancreaticoduodenal arteries. The gastroduodenal artery was absent. Dorsal pancreatic agenesis was confirmed, with the absence of the pancreatic body and tail. This configuration places the rCHA at high intraoperative risk and eliminates a major coeliac–SMA collateral route. Detailed preoperative vascular mapping and tailored surgical strategies are essential to prevent catastrophic ischemia during pancreatic or hepatic surgery and to guide appropriative operative approach.
2.Prevalence of variants in gonadal vessels:a systematic review with meta-analysis
Ioannis PASCHOPOULOS ; George TRIANTAFYLLOU ; Vasileios EDIAROGLOU ; Nikolaos ARKADOPOULOS ; Rǎzvan Costin TUDOSE ; Mugurel Constantin RUSU ; George TSAKOTOS ; Juan Jose VALENZUELA-FUENZALIDA ; Maria PIAGKOU
Anatomy & Cell Biology 2025;58(4):561-569
Gonadal arteries (GAs) and gonadal veins (GVs) display substantial anatomical variation, which has direct implications for surgical procedures, radiological interpretation, and fertility management. This study aimed to systematically review and meta-analyze the prevalence, origin, course, and drainage patterns of gonadal vessels in human anatomy. A systematic review and meta-analysis were conducted in line with current Evidence-Based Anatomy and PRISMA 2020 guidelines. A comprehensive search of major databases and anatomical journals yielded 31 eligible studies, comprising data on 2,875 gonadal vessels. The typical GA anatomy (single artery arising from the abdominal aorta) was observed in 98.72% of cases. Accessory GAs were found in 1.12%, most commonly arising from the renal artery (5.52%), with rare origins (<0.01%) from the accessory renal or suprarenal arteries. A normal arterial course was present in 90.24%, while an arched course occurred in 9.76%. The typical GV pattern (single vein draining into the inferior vena cava [IVC] or renal vein) was seen in 94.97%, and accessory GVs in 5.03%. The right GV drained into the IVC in 96.51%, with aberrant drainage to the right renal vein in 4.41%. The left GV drained into the left renal vein in 95.35%, with aberrant IVC drainage in 4.17%. Although the typical gonadal vascular anatomy predominates, variants, especially in GA origin and GV drainage, are not rare and must be recognized. These findings underscore the clinical importance of anatomical awareness in surgical planning, radiological evaluation, and the management of urological and reproductive conditions.
3.Does ductal lavage assert its role as a noninvasive diagnostic modality to identify women at low risk of breast cancer development?.
Ioanna KONSTANDIADOU ; Aikaterini MASTORAKI ; Olympia KOTSILIANOU ; Petros KARAKITSOS ; George ATHANASAS ; Vasilios SMYRNIOTIS ; Nikolaos ARKADOPOULOS
Journal of Gynecologic Oncology 2012;23(2):110-114
OBJECTIVE: Ductal lavage (DL) involves evaluation of the ductal system of the breast for detection of intra-ductal carcinomas and precursor lesions by collecting breast epithelial cells using a small-gauge catheter inserted into a ductal orifice on the nipple. The aim of this survey was to analyze cytologic features of samples obtained from low-risk women with DL and to elucidate the efficacy of this diagnostic modality in evaluating fluid production, cannulating and determining atypical breast epithelial cells. METHODS: Into this prospective study were consecutively registered 80 women between ages 28 to 67. Nipple aspiration was performed to identify all fluid-yielding ducts. According to the grading of specific features the interpretation of the sample included: normal/benign (category, 0), mild atypical (category, I), markedly atypical (category, II) or malignant (category, III) disorders. RESULTS: Ninety five percent (316/334) of the nipple aspirate fluid samples were classified as category 0, 4.8% (16/334) as category I and 0.2% (2/334) as category II changes. Category III disorders were not detected. Therefore, in 80% of the women examined results were within normal limits while 17.5% of the participants presented mild atypical and 2.5% markedly atypical rates. CONCLUSION: DL collection procedure proved to be rapid as well as acceptable by the women studied. It retains the advantage over other methods of nipple aspirate fluid in that it is easy to perform, thereby removing most clinician variability. It also helped low risk women to discriminate those with breast disorders that require additional investigation, further follow-up or administration of preventive medication.
Breast
;
Breast Neoplasms
;
Catheters
;
Epithelial Cells
;
Female
;
Humans
;
Imidazoles
;
Nipple Aspirate Fluid
;
Nipples
;
Nitro Compounds
;
Prospective Studies
;
Therapeutic Irrigation

Result Analysis
Print
Save
E-mail