1.Cyberbullying among Hanoi medical university students and some associated factors in 2023
Tran Quynh Anh ; Nguyen Thi Phuong Oanh ; Ha Tuan Dung ; Tran Minh Hai ; Dang Quang Tan ; Ngo Toan Anh
Vietnam Journal of Public Health 2025;11(1):2-
Objectives: The rapid and widespread development of social networking sites has created a potential venue for an increase in cyberbullying among adolescents. While much research has been done on middle school/high school students, this issue for college/university students has yet to receive much attention. The present study described the prevalence of cyberbullying and associated factors among Hanoi Medical University students.
Methods: Data were obtained from an online survey of conveniently selected Hanoi Medical University students. A total of 736 students participated and finished a structured questionnaire based on the Cyberbullying Victimization Scale (CVS).
Results: The prevalence of cyberbullying victims among Hanoi Medical University students was 17.4%, and 9.0% of the students had engaged in cyberbullying behaviors. Research also indicated that there is an association between cyberbullying behavior and factors such as internet usage duration and frequency of monitoring violent information. Gender didn't have any relationship with cyberbullying victimization but had a significant association with cyberbullying perpetration (OR = 2.37, 95%CI = 1.42 – 3.96).
Conclusion: Cyberbullying has become an important phenomenon related to internet usage duration and violent information among students of Hanoi Medical University. Therefore, it is necessary to build healthy internet habits and manage online information to reduce cyberbullying prevalence and promote student health in the digital age.
2.Outcomes of liver transplantation for hepatocellular carcinoma:Experiences from a Vietnamese center
Khai Viet NINH ; Dang Hai DO ; Trung Duc NGUYEN ; Phuong Ha TRAN ; Tuan HOANG ; Dung Thanh LE ; Nghia Quang NGUYEN
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(1):34-41
Background:
s/Aims: Liver transplantation (LT) provides a favorable outcome for patients with hepatocellular carcinoma (HCC) and was launched in Vietnam in 2004. In this study, we evaluated the short-term and long-term outcomes of LT and its risk factors.
Methods:
This retrospective study analyzed HCC patients who underwent LT at Viet Duc University hospital, Vietnam, from 01/2012–03/2022. The following data were gathered: demographics, virus infection, tumor characteristics, alpha-fetoprotein (AFP) level, Child-Pugh and MELD scores, selection criteria, type of LT, complications, 30-day mortality, and disease-free and overall survival (DFS and OS).
Results:
Fifty four patients were included, the mean age was 55.39 ± 8.46 years. Nearly 90% had hepatitis B virus-related HCC. The median (interquartile range) AFP level was 16.2 (88.7) ng/mL. The average MELD score was 10.57 ± 5.95; the rate of Child-Pugh A and B were 70.4% and 18.5%, respectively. Nearly 40% of the patients were within Milan criteria, brain-dead donor was 83.3%. Hepatic and portal vein thrombosis occurred in 0% and 1.9%, respectively; hepatic artery thrombosis 1.9%, biliary leakage 5.6%, and postoperative hemorrhage 3.7%. Ninety-day mortality was 5.6%. Five-year DFS and OS were 79.3% and 81.4%, respectively. MELD score and ChildPugh score were predictive factors for DFS and OS (p < 0.05). In multivariate analysis, Child-Pugh score was the only significant factor (p < 0.05).
Conclusions
In Vietnam, LT is an effective therapy for HCC with an acceptable complication rate, mortality rate, and good survival outcomes, and should be further encouraged.
3.Successful surgical interventions for a giant and complicated myoepithelial carcinoma: a case report
Quang Vinh VU ; Thanh Tuan HOANG ; Van Anh TRAN ; Thanh Hai TONG ; Hong Ha NGUYEN
Archives of Craniofacial Surgery 2024;25(4):197-200
Ethmoid myoepithelial carcinoma is a rare tumor, with only 14 cases reported to date. This report discusses the largest tumor of this type ever recorded in the ethmoid region. The tumor caused extensive damage to facial structures, complicating treatment. The patient’s age and comorbidities increased the risk of intraoperative bleeding, presenting challenges to the complete removal of the tumor and the reconstruction of the damaged structures. To reduce the risk of intraoperative hemorrhage, shorten the surgery time, and manage potential heartrelated complications, arterial embolization was performed using gelatin sponges and coils. Definitive surgery was then carried out using a skin flap and mucosal flap to successfully reconstruct the defect. Postoperative radiotherapy was deemed unnecessary. The patient recovered well, with a satisfactory aesthetic outcome. No recurrence was observed during a 3-year follow-up period.
4.Economic Burden of Chronic Obstructive Pulmonary Disease: A Systematic Review
Hai Quang PHAM ; Kiet Huy Tuan PHAM ; Giang Hai HA ; Tin Trung PHAM ; Hien Thi NGUYEN ; Trang Huyen Thi NGUYEN ; Jin-Kyoung OH
Tuberculosis and Respiratory Diseases 2024;87(3):234-251
Globally, providing evidence on the economic burden of chronic obstructive pulmonary disease (COPD) is becoming essential as it assists the health authorities to efficiently allocate resources. This study aimed to summarize the literature on economic burden evidence for COPD from 1990 to 2019. This study examined the economic burden of COPD through a systematic review of studies from 1990 to 2019. A search was done in online databases, including Web of Science, PubMed/Medline, Scopus, and the Cochrane Library. After screening 12,734 studies, 43 articles that met the inclusion criteria were identified. General study information and data on direct, indirect, and intangible costs were extracted and converted to 2018 international dollars (Int$). Findings revealed that the total direct costs ranged from Int$ 52.08 (India) to Int$ 13,776.33 (Canada) across 16 studies, with drug costs rannging from Int$ 70.07 (Vietnam) to Int$ 8,706.9 (China) in 11 studies. Eight studies explored indirect costs, while one highlighted caregivers’ direct costs at approximately Int$ 1,207.8 (Greece). This study underscores the limited research on COPD caregivers’ economic burdens, particularly in developing countries, emphasizing the importance of increased research support, particularly in high-resource settings. This study provides information about the demographics and economic burden of COPD from 1990 to 2019. More strategies to reduce the frequency of hospital admissions and acute care services should be implemented to improve the quality of COPD patients’ lives and reduce the disease’s rising economic burden.
5.EVALUATE THE IMPACT OF CHILDREN’S MALADAPTIVE BEHAVIOR MANAGEMENT PROGRAM ON PARTICIPATING GRANDPARENTS IN VIETNAM: A RANDOMIZED CONTROLLED TRIAL
Yen Tran Thi Hai ; Nga Chu Thi Huong ; Thoa Dinh Thi ; Thuy Cao Thi ; Thang Nguyen Anh
ASEAN Journal of Psychiatry 2024;25(6):1-11
EVALUATE THE IMPACT OF CHILDREN’S MALADAPTIVE BEHAVIOR MANAGEMENT PROGRAM ON PARTICIPATING GRANDPARENTS IN VIETNAM: A RANDOMIZED CONTROLLED TRIAL
In the Vietnamese cultural context, grandparents often assist their children in raising
their grandchildren. While children often exhibit maladaptive behaviors, grandparents
show difficulty in dealing with those behaviors of their grandchildren. This article
evaluates the effectiveness of children’s maladaptive behavior management program for
participating grandparents in order to propose recommendations for completing and
widely implementing a program to support grandparents to manage their grandchildren
behaviors. The results of the repeated measures Analysis of Variance (ANOVA) analysis
of the cognitive status, emotions and skills of the grandparents before the experiment,
immediately after the experiment and three months after the experiment between
grandparents of the intervention group and grandparents of the control group show that:
The program is effective in enhancing grandparents’ awareness and skills in managing
children’s maladaptive behavior, reducing the impact of children’s maladaptive behavior
on grandparents’ emotions. This result shows that it is feasible to implement a training
program for grandparents to manage children’s maladaptive behavior in Vietnam. ASEAN
Journal of Psychiatry, Vol. 25 (6 ) August, 2024; 1-11.
6.Assessment of In vitro Antioxidant, Antidiabetic and Cytotoxic Activities of Sphaeranthus africanus Extracts
Tran Thi HUYEN ; Julien DUJARDIN ; Nguyen Thi THU HUONG ; Chung Thi MY DUYEN ; Nguyen Hoang MINH ; Ha Quang THANH ; Dao Tran MONG ; Ly Hai TRIEU ; Nguyen Mai TRUC TIEN ; Mai Thanh CHUNG ; Nguyen Nhat MINH ; Nguyen Thi NGOC DAN ; Huynh LOI
Natural Product Sciences 2023;29(2):98-103
Sphaeranthus africanus is commonly used as a traditional remedy for sore throats and pain treatment in Vietnam. The aerial parts have been studied for its anti-inflammatory and anti-proliferative properties. However, the antioxidant and antidiabetic potential of the plant has not been explored. In this work, hydrophilic extracts of the plant's aerial parts were prepared in order to investigate its antioxidant and anti-diabetic properties. Also, the cytotoxicity of the root was evaluated and compared to that of the aerial parts. All of the extracts inhibited lipid peroxidation with IC 50 values ranging from 2.05 to 3.56 µg/mL, indicating substantial antioxidant activity. At an IC 50 value of 4.80 μg/mL, the 50% ethanol extract exhibited the most potent inhibition of α-glucosidase. The cytotoxic activity of root extracts is 2 to 5-fold less than that of the aerial parts. Nevertheless, dichloromethane and ethyl acetate extracts of the root demonstrated a selective effect on leukemia cells, with no harm towards the normal HEK-293 cell line. This work provides a scientific support for the antioxidant and antidiabetic activity of the plant. Hence, it may find a promising material for the development of novel antioxidant and antidiabetic agents. More research can be conducted on the phytochemistry and anticancer activities of the plant’s root.
7.Acute Extrapyramidal Side Effects Following Domperidone Intake in a 48-Year-Old Female Patient: The First Genetic Alteration and Drug Interaction Characterized
Nguyen Duc THUAN ; Vu Phuong NHUNG ; Hoang Thi DUNG ; Nhu Dinh SON ; Nguyen HAI HA ; Nguyen Dang TON
Journal of Movement Disorders 2022;15(2):193-195
8.Understanding the COVID-19 Infodemic: Analyzing User-Generated Online Information During a COVID-19 Outbreak in Vietnam
Ha-Linh QUACH ; Thai Quang PHAM ; Ngoc-Anh HOANG ; Dinh Cong PHUNG ; Viet-Cuong NGUYEN ; Son Hong LE ; Thanh Cong LE ; Dang Hai LE ; Anh Duc DANG ; Duong Nhu TRAN ; Nghia Duy NGU ; Florian VOGT ; Cong-Khanh NGUYEN
Healthcare Informatics Research 2022;28(4):307-318
Objectives:
Online misinformation has reached unprecedented levels during the coronavirus disease 2019 (COVID-19) pandemic. This study analyzed the magnitude and sentiment dynamics of misinformation and unverified information about public health interventions during a COVID-19 outbreak in Da Nang, Vietnam, between July and September 2020.
Methods:
We analyzed user-generated online information about five public health interventions during the Da Nang outbreak. We compared the volume, source, sentiment polarity, and engagements of online posts before, during, and after the outbreak using negative binomial and logistic regression, and assessed the content validity of the 500 most influential posts.
Results:
Most of the 54,528 online posts included were generated during the outbreak (n = 46,035; 84.42%) and by online newspapers (n = 32,034; 58.75%). Among the 500 most influential posts, 316 (63.20%) contained genuine information, 10 (2.00%) contained misinformation, 152 (30.40%) were non-factual opinions, and 22 (4.40%) contained unverifiable information. All misinformation posts were made during the outbreak, mostly on social media, and were predominantly negative. Higher levels of engagement were observed for information that was unverifiable (incidence relative risk [IRR] = 2.83; 95% confidence interval [CI], 1.33–0.62), posted during the outbreak (before: IRR = 0.15; 95% CI, 0.07–0.35; after: IRR = 0.46; 95% CI, 0.34-0.63), and with negative sentiment (IRR = 1.84; 95% CI, 1.23–2.75). Negatively toned posts were more likely to be misinformation (odds ratio [OR] = 9.59; 95% CI, 1.20–76.70) or unverified (OR = 5.03; 95% CI, 1.66–15.24).
Conclusions
Misinformation and unverified information during the outbreak showed clustering, with social media being particularly affected. This indepth assessment demonstrates the value of analyzing online “infodemics” to inform public health responses.
9.Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam
Vu VAN KHIEN ; Duong Minh THANG ; Tran Manh HAI ; Nguyen Quang DUAT ; Pham Hong KHANH ; Dang Thuy HA ; Tran Thanh BINH ; Ho Dang Quy DUNG ; Tran Thi Huyen TRANG ; Yoshio YAMAOKA
Gut and Liver 2019;13(5):483-497
Antibiotic resistance is the most important factor leading to the failure of eradication regimens. This review focuses on the prevalence of Helicobacter pylori primary and secondary resistance to clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug in Vietnam. We searched the PubMed, EMBASE, Vietnamese National Knowledge Infrastructure, and Vietnamese Biomedical databases from January 2000 to December 2016. The search terms included the following: H. pylori infection, antibiotic (including clarithromycin, metronidazole, amoxicillin, levofloxacin, tetracycline, and multidrug) resistance in Vietnam. The data were summarized in an extraction table and analyzed manually. Finally, Excel 2007 software was used to create charts. Ten studies (three studies in English and seven in Vietnamese) were included in this review. A total of 308, 412, 523, 408, 399, and 268 H. pylori strains were included in this review to evaluate the prevalence of H. pylori primary resistance to amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance, respectively. Overall, the primary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 15.0%, 34.1%, 69.4%, 27.9%, 17.9% and 48.8%, respectively. Secondary resistance rates of amoxicillin, clarithromycin, metronidazole, levofloxacin, tetracycline, and multidrug resistance were 9.5%, 74.9%, 61.5%, 45.7%, 23.5% and 62.3%, respectively. In Vietnam, primary and secondary resistance to H. pylori is increasing over time and affects the effectiveness of H. pylori eradication.
Amoxicillin
;
Asian Continental Ancestry Group
;
Bismuth
;
Clarithromycin
;
Drug Resistance, Microbial
;
Drug Resistance, Multiple
;
Helicobacter pylori
;
Helicobacter
;
Humans
;
Levofloxacin
;
Metronidazole
;
Prevalence
;
Tetracycline
;
Vietnam
10.Identification of Enterovirus C105 for the first time in New Zealand
Cong Thanh Duong ; Tran Hien Nguyen ; Anh Tuan Nguyen ; Thi Thanh Ha Hoang ; Hong Thang Pham ; Thi THanh Ha Nguyen ; Anh Tuan Le ; Dai Quang Tran ; Hong Tram Tran ; Le Hai Nguyen ; Thi Thu Huong Phan ; Hai Son Vo ; Hoang Duc Bui ; Thien Nga Nguyen ; David Jacka ; Keith Sabin
Western Pacific Surveillance and Response 2015;6(1):52-54
In this report we describe a new approach in HIV sentinel surveillance that was piloted in Viet Nam in 2009 and is currently being rolled out in all provinces. It comprises a brief behavioural questionnaire added to the HIV sentinel surveillance surveys conducted routinely among people who inject drugs, female sex workers and men who have sex with men. Timely reporting of data from this system has resulted in improvements to HIV prevention efforts for most at-risk populations.


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