Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes. Current treatment methods typically focus on controlling blood glucose levels, routine care, anti-infection, debridement, and other aspects. However, these approaches have not consistently yielded satisfactory results. Adipose-derived stem cells (ADSCs) are characterized by their diverse sources, ease of acquisition, and low immunogenicity, making them a prominent topic of research area in the field of stem cells. ADSCs have emerged as a new strategy for the treatment of DFUs. This review aims to describe the pathophysiological characteristics of diabetic foot ulcers, the advantages and biological functions of ADSCs, and their mechanisms for promoting wound healing in DFUs, thereby providing a theoretical basis for the clinical application of ADSCs in the treatment of DFUs.

Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes. The current treatment method usually focus on blood glucose controlling, routine care, anti-infection, debridement and other aspects, but still have not achieved good result . Adipose-derived stem cells (ADSCs) possess the characteristics of a wide range of sources, easy acquisition, and low immunogenicity, making them hot topics of research area in the field of stem cell. ADSCs has become a new strategy for the treatment of DFUs . This review aims to describe the pathophysiological characteristics of diabetic foot ulcers, the advantages and biological function of ADSCs and their mechanisms of promoting DFUs wound healing, to provide a theoretical basis for the clinical application of ADSCs in the treatment of DFUs.

Diabetic foot ulcers (DFUs) are a common and serious complication of diabetes. The current treatment method usually focus on blood glucose controlling, routine care, anti-infection, debridement and other aspects, but still have not achieved good result . Adipose-derived stem cells (ADSCs) possess the characteristics of a wide range of sources, easy acquisition, and low immunogenicity, making them hot topics of research area in the field of stem cell. ADSCs has become a new strategy for the treatment of DFUs . This review aims to describe the pathophysiological characteristics of diabetic foot ulcers, the advantages and biological function of ADSCs and their mechanisms of promoting DFUs wound healing, to provide a theoretical basis for the clinical application of ADSCs in the treatment of DFUs.