1.Pre-operative Factors Predicting Mortality in Six Months and Functional Recovery in Elderly Patients with Hip Fractures
Nam NH ; Minh ND ; Hai TX ; Sinh CT ; Loi CB ; Anh LT
Malaysian Orthopaedic Journal 2023;17(No.1):10-17
Introduction: This study aimed to determine on-admission
and perioperative factors predicting six-month mortality and
functional recovery in Vietnamese patients with hip fracture.
Materials and methods: Between April 2020 and July
2021, 118 patients participated in this prospective study.
Patients’ data were collected from medical records. Harris
hip score (HHS) was used to evaluate the functional recovery
six months after fractures. The obtained data were analysed
using a univariate and multivariate model.
Results: The mean age of the participants was 79.5±9.4
years and 68.6% of the patients were female. The six-month
mortality rate was 5.9% and independently associated with
age (odds ratio (OR): 3.512, 95% confidence interval (CI)
1.538 – 8.019; P<0.001, patients aged >80 years vs those
aged ≤80 years) and hypoproteinemia (OR: 2.859, 95% CI:
1.001 – 8.166, P=0.049). Among 111 survivors there were 66
(59.5%) of patients with a good functional recovery. Patients
aged >80 years had a higher risk of poor functional outcome
(OR: 3.167, 95% CI: 1.386 – 7.235, P: 0.006) compared to
those aged ≤ 80 years. No significant correlations between
other clinical (gender, body mass index, comorbidities, type
of fractures or surgery, time until surgery) or laboratory
parameters (anaemia, hyperglycemia, marked elevation of C
reactive protein level, electrolyte abnormalities, elevated
urea) and mortality or functional outcome were found.
Conclusion: Advanced age is the most important factor
affecting both mortality and functional outcome while
hypoproteinemia is associated with a higher risk of mortality
in elderly patients with hip fractures.
2.Environmental sampling for SARS-CoV-2 at a reference laboratory and provincial hospital in central Viet Nam, 2020
Thá ; i Hù ; ng Đỗ ; Văn Thà ; nh Nguyễn ; Thế Hù ; ng Đinh ; Xuâ ; n Huy Lê ; ; Quang Chiê ; u Nguyễn ; Văn Quâ ; n Lê ; ; Bảo Triệu Nguyễn ; Ngọc Bí ; ch Ngâ ; n Nguyễn ; Thị Ngọc Phú ; c Nguyễn ; Kim Mai Huỳnh ; Hoà ; ng Long Trịnh ; Thị Kim Trang Lê ; ; Thù ; y Dung Diệp ; Thủy Thị Thu Đỗ ; Hiền Thị Thu Bù ; i ; Alyssa M Finlay ; Quốc Việt Nguyễn ; Philip L Gould
Western Pacific Surveillance and Response 2021;12(3):47-55
Objective: To determine whether environmental surface contamination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred at a provincial hospital in Viet Nam that admitted patients with novel coronavirus disease 2019 (COVID-19) and at the regional reference laboratory responsible for confirmatory testing for SARS-CoV-2 in 2020.
Methods: Environmental samples were collected from patient and staff areas at the hospital and various operational and staff areas at the laboratory. Specimens from frequently touched surfaces in all rooms were collected using a moistened swab rubbed over a 25 cm2 area for each surface. The swabs were immediately transported to the laboratory for testing by real-time reverse transcription polymerase chain reaction (RT-PCR). Throat specimens were collected from staff at both locations and were also tested for SARS-CoV-2 using real-time RT-PCR.
Results: During the sampling period, the laboratory tested 6607 respiratory specimens for SARS-CoV-2 from patients within the region, and the hospital admitted 9 COVID-19 cases. Regular cleaning was conducted at both sites in accordance with infection prevention and control (IPC) practices. All 750 environmental samples (300 laboratory and 450 hospital) and 30 staff specimens were negative for SARS-CoV-2.
Discussion: IPC measures at the facilities may have contributed to the negative results from the environmental samples. Other possible explanations include sampling late in a patient’s hospital stay when virus load was lower, having insufficient contact time with a surface or using insufficiently moist collection swabs. Further environmental sampling studies of SARS-CoV-2 should consider including testing for the environmental presence of viruses within laboratory settings, targeting the collection of samples to early in the course of a patient’s illness and including sampling of confirmed positive control surfaces, while maintaining appropriate biosafety measures.


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