Background: Analyzing registered drug information and providing policymakers and decision-makers with evidence-based data is essential for future decision-making. Aim: To determine composition and patterns of change in registered medicines in Mongolia. Materials and Methods: In this study, an overview analysis of drug registration data from 2006 to 2025 was carried out using Microsoft Power BI. Result: During this period, a total of 7,528 drugs were registered, of which 77.3% were modern medicines, 15.1% were traditional medicines, 5.6% were herbal medicines, 1.4% were biopreparations, and 0.6% were vaccines. On average, overall drug registration increased annually by 2.2%, while imported drug registration grew by 1.9%. In contrast, domestic drug registration fell by 1.4%. Of all registered drugs, 79.7% were imported. Drugs from 64 countries were registered, with Mongolia contributing the largest share by registering 1,525 drugs, which accounts for 20.3% of the total. Among drugs registered by 33 countries with strict regulatory systems, 42.5% of total registrations and 53.3% of imported drugs originated from these countries. Of all registered medicines, 68.2% were prescription medicines, 28.3% were overthe-counter medicines, 1.2% were hospital-use medicines, 2.2% were narcotics, and 0.3% were psychotropic substances. In terms of routes of administration, 64.2% were oral medicines, 23.7% were injectable, 4.8% were ophthalmic, otic, or nasal preparations, 4.6% were topical medicines, 2% were administered via other routes, and 0.9% were inhaled. According to the ATC classification, the largest share was held by anti-infective medicines at 19.5%, while antiparasitic and insecticidal preparations had the smallest share at 0.76%. As of 4 April 2026, there were 477 antibiotics registered, of which 412 were other than suppositories, ointments, eye drops, and ear drops. According to the WHO AWaRe classification list for 2025, 49.03% (n=202) was “Access” group of antibiotics. Conclusion The findings of this study indicate that imported medicines account for a significant share of registered drugs in Mongolia, underscoring the need to expand domestic pharmaceutical production and strengthen the drug registration system.