Objective To explore the impact of Video-Assisted Protrusion Treatment with Endoscope(VPTED)on red blood cell immunity,complications,and lumbar extensor muscle groups in patients with lumbar disc herniation(LDH).Methods A total of 103 LDH patients in our hospital from March 2021 to March 2023 were prospectively selected.Among them,6 cases were lost to follow-up,and 97 cases were included in the study.They were divided into the observation group(49 cases)and the control group(48 cases)by random number table method,and VPTED and microscopic minimally invasive channel technique(MITM)were performed respectively.The perioperative indicators,complications,and excellent and good rates of the two groups were statistically analyzed.The tissue trauma indicators interleukin-6(IL-6),IL-8,IL-17,red blood cell immune indicators,Oswestry disability index(ODI),and biomechanical indicators of the lumbar and dorsal extensor muscle group(peak moment,average power,and lumbar and dorsal flexion and extension ratio in the lumbar and dorsal extension state)before and after the operation were compared between the two groups.Results The surgical time,mobilization time,and hospitalization time of the observation group were(68.62±5.59)minutes,(1.44±0.31)days,and(7.24±1.08)days,respectively,which were shorter than those of the control group[(94.11±10.34)minutes,(2.38±0.46)days,and(9.26±1.23)days].The intraoperative blood loss and VAS scores at 3 and 5 days after surgery were(12.68±2.37)ml,(2.78±0.34)points and(1.45±0.33)points,respectively.Which were lower than those of the control group[(50.54±4.49)ml,(3.31±0.36)points and(2.12±0.40)points](P＜0.05).The incision length of the observation group was(0.87±0.21)cm,which was shorter than that of the control group[(1.23±0.26)cm].There was a statistically significant difference between the two groups(P＜0.05).From pre-operation to 7 days post-operation,the levels of IL-6,IL-17,IL-8,and RBC-ICR in both groups exhibited an increase-decrease trend,while RBC-C3bRR and RBC-NTFR showed a decrease-increase trend(P＜0.05).From pre-operation to 12 months post-operation,the ODI index and lumbar back flexion-extension ratio in both groups decreased with time,while peak torque and average power in lumbar back extension increased with time(P＜0.05).At 12 months post-operation,there were no statistically significant differences in complication rates(2.04％vs 6.25％)and surgical excellence rates(89.80％vs 87.50％)between the two groups(P＞0.05).Conclusion VPTED is safe and effective in the treatment of LDH,and has unique advantages in the improvement of perioperative indexes.

Objective To explore the impact of Video-Assisted Protrusion Treatment with Endoscope(VPTED)on red blood cell immunity,complications,and lumbar extensor muscle groups in patients with lumbar disc herniation(LDH).Methods A total of 103 LDH patients in our hospital from March 2021 to March 2023 were prospectively selected.Among them,6 cases were lost to follow-up,and 97 cases were included in the study.They were divided into the observation group(49 cases)and the control group(48 cases)by random number table method,and VPTED and microscopic minimally invasive channel technique(MITM)were performed respectively.The perioperative indicators,complications,and excellent and good rates of the two groups were statistically analyzed.The tissue trauma indicators interleukin-6(IL-6),IL-8,IL-17,red blood cell immune indicators,Oswestry disability index(ODI),and biomechanical indicators of the lumbar and dorsal extensor muscle group(peak moment,average power,and lumbar and dorsal flexion and extension ratio in the lumbar and dorsal extension state)before and after the operation were compared between the two groups.Results The surgical time,mobilization time,and hospitalization time of the observation group were(68.62±5.59)minutes,(1.44±0.31)days,and(7.24±1.08)days,respectively,which were shorter than those of the control group[(94.11±10.34)minutes,(2.38±0.46)days,and(9.26±1.23)days].The intraoperative blood loss and VAS scores at 3 and 5 days after surgery were(12.68±2.37)ml,(2.78±0.34)points and(1.45±0.33)points,respectively.Which were lower than those of the control group[(50.54±4.49)ml,(3.31±0.36)points and(2.12±0.40)points](P＜0.05).The incision length of the observation group was(0.87±0.21)cm,which was shorter than that of the control group[(1.23±0.26)cm].There was a statistically significant difference between the two groups(P＜0.05).From pre-operation to 7 days post-operation,the levels of IL-6,IL-17,IL-8,and RBC-ICR in both groups exhibited an increase-decrease trend,while RBC-C3bRR and RBC-NTFR showed a decrease-increase trend(P＜0.05).From pre-operation to 12 months post-operation,the ODI index and lumbar back flexion-extension ratio in both groups decreased with time,while peak torque and average power in lumbar back extension increased with time(P＜0.05).At 12 months post-operation,there were no statistically significant differences in complication rates(2.04％vs 6.25％)and surgical excellence rates(89.80％vs 87.50％)between the two groups(P＞0.05).Conclusion VPTED is safe and effective in the treatment of LDH,and has unique advantages in the improvement of perioperative indexes.

Objective To analyze the effects of different doses of naloxone on resuscitation of patients with quality of dezocine anesthesia.Methods 84 patients with dezocine anesthesia surgery were selected and divided into three groups in accordance with the use of naloxone plus volume,28 cases in each group.All patients were treated with vein injection of propofol,fentanyl and Shun type atracurium for induction of anesthesia,endotracheal intubation and mechanical ventilation were given dezocine infusion to maintain anesthesia.After the operation,the high dose group was given 14μg/kg naloxone,the low dose group was given 7μg/kg naloxone,and the control group only received intravenous infusion of the corresponding measurement.Mean arterial pressure (map),heart rate (HR)before anes-thesia,recovery,extubation and intubation after 10min of three groups were observed.Pain and sedation situation score of the patients regained consciousness after 1min,1h,2h were received by visual analogue scale (VAS),sedation/restlessness score (SAS).At the same time,the incidence of complications and adverse reactions of the three groups were recorded.Results There were no significant differences in MAP and HR indexes among the three groups before anesthesia.At resuscitation and extubation there were no differences in MAP and HR between the low dose group and the control group (all P >0.05).However,resuscitation,extubation,MAP and HR were significantly lower in the low dose group than those in the high dose group (all P <0.05).The difference of VAS,SAS score had no statistical sig-nificance between the low dose group waken up each time and control group,but the VAS,SAS score in the high dose group waken up each time were significantly higher than those in the control group and low dose group(all P <0.05). The respiratory inhibition in the high dose group and low dose group were significantly lower than those of the control group(0,3.57% and 10.71%;χ2 =4.169,1.077,all P <0.05),but nausea and vomiting in the high dose group were higher than those in the control group and low dose group(all P <0.05).Conclusion Different doses of nalox-one could be used for patients using dezocine anesthesia according to patients after operation,to reduce respiratory inhibi-tion,and help patients relieve pain and agitation,and the recommend dose of naloxone is 7μg/kg.