Objective: This study investigates the effectiveness of the Loving-Kindness and Mindfulness Meditation (LKM) therapy in improving mood states of hematologic malignancy patients in a sterile isolation room. A randomized controlled trial was conducted, with the POMS2 Japanese version used to assess mood state improvement. Methods: The final number of participants in this study was nine (intervention group n=4, control group n=5). Patients in a sterile isolation room were provided with a tablet containing a video of the LKM. The intervention group watched the 20-minute video. POMS2 factor scores were measured before the intervention and again one and two weeks after the intervention. The data were analyzed using two-way analysis of variance (ANOVA) to compare the scores across time points. Results: No statistically significant differences were observed between the two groups for each factors; however, a trend of nonlinear change was observed in the Vigor-Apathy (VA) factor(p=0.054). Conclusion: In this pilot study, LKM did not show a significant effect on the mood state of patients, which is suggested to be due to the insufficient number of cases. It seems necessary to increase the number of subjects in future research.

Objective: In this practical study, mindfulness-based “Loving-Kindness and Mindfulness Meditation” was carried out for breast cancer patients. Methods: 60-minute meditation sessions were carried out every two weeks for a total of four sessions. At Month 1 and in the period up to Month 3 after intervention, changes in quality of life (QOL) were assessed using SF-36 v2 for a total of five times. Participants were taught to practice meditation at home, and their daily meditation experiences were written down as records. Results: Participants were divided into two groups, with two subjects in the intervention group and one subject in the non-intervention group. RCS based on SF-36 v2 were in the intervention group, and could be maintained or improved even one month after completion of intervention compared to before intervention. The records were divided into “Introduction phase” (for meditation in the first intervention); “Acquisition phase” (in and after the second); “Stable phase” (in and after the third); and “Establishment phase” (in and after the fourth). Correspondence analysis was performed for the fourth term by Text Mining. Conclusion: During early intervention at the “Introduction phase,” intentional concentration on what is occurring is carried out. As meditations continue, a change in the sense of self-consciousness, which cannot be experienced in daily life, is thought to occur.