1.Nurse retention discourse in YouTube comments: a structural topic modeling analysis
Journal of Korean Academy of Nursing 2026;56(2):206-219
Purpose:
This study analyzed public discourse on nurse retention through YouTube comments posted between 2018 and 2024 to examine how retention issues are collectively framed in online public spheres, thereby extending individual-level retention research to societal-level discourse analysis.
Methods:
Comments were collected from 226 YouTube videos uploaded between January 2015 and December 2024, identified using search terms that combined “nurse” with retention-related keywords. After duplicates and comments posted outside the study period were removed, 32,399 comments were analyzed using structural topic modeling with year and number of likes as covariates. Topic correlation network analysis with community detection was used to identify discourse coalitions.
Results:
Fourteen substantive topics and one noninterpretive topic emerged, spanning individual coping strategies, organizational workplace issues, and systemic policy structures. “International nursing migration and career pathways” (12.8%) and “Disputes regarding the scope of practice among professionals” (11.4%) were the most prevalent topics. Temporal analysis revealed discourse shifts consistent with focusing events theory: COVID-19 (coronavirus disease 2019) activated structural critique frames while suppressing career mobility discourse; the 2022 Nursing Law followed an issue-attention cycle pattern; and the 2024 medical school quota expansion embedded retention discourse within broader healthcare policy debates. Network analysis identified two discourse communities, professional identity and structural exploitation, with international migration serving as a bridging frame across both.
Conclusion
Public discourse framed nurse retention as a systemic and structural issue rather than as an expression of individual professional rejection. These collective framing patterns complement traditional survey-based research and may inform policy design by identifying which frames achieve public resonance and where discourse fragmentation may challenge policy implementation.
2.Analysis of Factors Related to Delirium in Hospitalized Cancer Patients in General Wards
Sojeong PARK ; Hyangkyu LEE ; Mona CHOI ; Hyejin KIM
Asian Oncology Nursing 2026;26(1):20-30
Purpose:
This study aimed to identify the incidence and related factors of delirium among cancer patients admitted to the general wards of a tertiary hospital.
Methods:
A retrospective analysis was performed on 9,749 adult cancer patients. Patients who screened positive for delirium were assessed using the Korean version of the Nursing Delirium Screening Scale (NuDESC). Data were analyzed using χ² tests, t-tests, and multiple logistic regression.
Results:
The incidence of delirium was 2.5% (n=243) based on screening results. Significant predictors included older age, longer hospital stays, emergency room admission, 90-day readmission, completion of life-sustaining treatment decisions, surgical department admission, altered consciousness (the strongest predictor), elevated white blood cell and blood urea nitrogen levels, and low albumin levels (p<.050).These 10 factors showed high discriminatory power for delirium (AUC=.91, 95% CI: 0.90~0.93).
Conclusion
The Nu-DESC should be actively utilized in clinical practice for early delirium detection. Nursing interventions must prioritize managing modifiable factors such as nutritional status, infection, and dehydration. Furthermore, case-sharing systems and regular education are essential to enhance nursing expertise and ensure patient safety.
3.Harnessing Institutionally Developed Clinical Targeted Sequencing to Improve Patient Survival in Breast Cancer: A Seven-Year Experience
Jiwon KOH ; Jinyong KIM ; Go-Un WOO ; Hanbaek YI ; So Yean KWON ; Jeongmin SEO ; Jeong Mo BAE ; Jung Ho KIM ; Jae Kyung WON ; Han Suk RYU ; Yoon Kyung JEON ; Dae-Won LEE ; Miso KIM ; Tae-Yong KIM ; Kyung-Hun LEE ; Tae-You KIM ; Jee-Soo LEE ; Moon-Woo SEONG ; Sheehyun KIM ; Sungyoung LEE ; Hongseok YUN ; Myung Geun SONG ; Jaeyong CHOI ; Jong-Il KIM ; Seock-Ah IM
Cancer Research and Treatment 2025;57(2):443-456
Purpose:
Considering the high disease burden and unique features of Asian patients with breast cancer (BC), it is essential to have a comprehensive view of genetic characteristics in this population. An institutional targeted sequencing platform was developed through the Korea Research-Driven Hospitals project and was incorporated into clinical practice. This study explores the use of targeted next-generation sequencing (NGS) and its outcomes in patients with advanced/metastatic BC in the real world.
Materials and Methods:
We reviewed the results of NGS tests administered to BC patients using a customized sequencing platform—FiRST Cancer Panel (FCP)—over 7 years. We systematically described clinical translation of FCP for precise diagnostics, personalized therapeutic strategies, and unraveling disease pathogenesis.
Results:
NGS tests were conducted on 548 samples from 522 patients with BC. Ninety-seven point six percentage of tested samples harbored at least one pathogenic alteration. The common alterations included mutations in TP53 (56.2%), PIK3CA (31.2%), GATA3 (13.8%), BRCA2 (10.2%), and amplifications of CCND1 (10.8%), FGF19 (10.0%), and ERBB2 (9.5%). NGS analysis of ERBB2 amplification correlated well with human epidermal growth factor receptor 2 immunohistochemistry and in situ hybridization. RNA panel analyses found potentially actionable and prognostic fusion genes. FCP effectively screened for potentially germline pathogenic/likely pathogenic mutation. Ten point three percent of BC patients received matched therapy guided by NGS, resulting in a significant overall survival advantage (p=0.022), especially for metastatic BCs.
Conclusion
Clinical NGS provided multifaceted benefits, deepening our understanding of the disease, improving diagnostic precision, and paving the way for targeted therapies. The concrete advantages of FCP highlight the importance of multi-gene testing for BC, especially for metastatic conditions.
4.Development of a Korean version of the Frailty Model with a Holistic Perspective: A Delphi Study
Ju Hee LEE ; Gwang Suk KIM ; Sanghee KIM ; Eunyoung KIM ; Layoung KIM ; Jee-Hye YOO
Journal of Korean Academy of Fundamental Nursing 2025;32(2):220-232
Purpose:
This study aimed to develop a Korean version of the frailty model that reflects a holistic perspective. There were three phases of the study: a literature review, a two-round Delphi study, and a public hearing.
Methods:
The model was developed based on the middle-range theory generation approach proposed by Roy. A literature search was conducted, and a review of 36 studies on frailty involving Koreans led to the development of an initial frailty model. A two-round Delphi study was then conducted with nine experts to evaluate the appropriateness of the model. The revised model was presented at a public hearing to achieve consensus. Based on feedback indicating the need for improved visualization, a finalized diagrammatic model was developed.
Results:
The final frailty model comprised four domains, seven subdomains, and 30 items. It included specific items reflecting the distinctive characteristics of Korean culture, such as relationships with adult children (filial piety), nutritional status (consumption of red meat), and type of residential building.
Conclusion
The final frailty model provides a comprehensive perspective on the factors contributing to frailty, their interactions, and the potential interventions that healthcare providers can implement to prevent frailty.
5.Harnessing Institutionally Developed Clinical Targeted Sequencing to Improve Patient Survival in Breast Cancer: A Seven-Year Experience
Jiwon KOH ; Jinyong KIM ; Go-Un WOO ; Hanbaek YI ; So Yean KWON ; Jeongmin SEO ; Jeong Mo BAE ; Jung Ho KIM ; Jae Kyung WON ; Han Suk RYU ; Yoon Kyung JEON ; Dae-Won LEE ; Miso KIM ; Tae-Yong KIM ; Kyung-Hun LEE ; Tae-You KIM ; Jee-Soo LEE ; Moon-Woo SEONG ; Sheehyun KIM ; Sungyoung LEE ; Hongseok YUN ; Myung Geun SONG ; Jaeyong CHOI ; Jong-Il KIM ; Seock-Ah IM
Cancer Research and Treatment 2025;57(2):443-456
Purpose:
Considering the high disease burden and unique features of Asian patients with breast cancer (BC), it is essential to have a comprehensive view of genetic characteristics in this population. An institutional targeted sequencing platform was developed through the Korea Research-Driven Hospitals project and was incorporated into clinical practice. This study explores the use of targeted next-generation sequencing (NGS) and its outcomes in patients with advanced/metastatic BC in the real world.
Materials and Methods:
We reviewed the results of NGS tests administered to BC patients using a customized sequencing platform—FiRST Cancer Panel (FCP)—over 7 years. We systematically described clinical translation of FCP for precise diagnostics, personalized therapeutic strategies, and unraveling disease pathogenesis.
Results:
NGS tests were conducted on 548 samples from 522 patients with BC. Ninety-seven point six percentage of tested samples harbored at least one pathogenic alteration. The common alterations included mutations in TP53 (56.2%), PIK3CA (31.2%), GATA3 (13.8%), BRCA2 (10.2%), and amplifications of CCND1 (10.8%), FGF19 (10.0%), and ERBB2 (9.5%). NGS analysis of ERBB2 amplification correlated well with human epidermal growth factor receptor 2 immunohistochemistry and in situ hybridization. RNA panel analyses found potentially actionable and prognostic fusion genes. FCP effectively screened for potentially germline pathogenic/likely pathogenic mutation. Ten point three percent of BC patients received matched therapy guided by NGS, resulting in a significant overall survival advantage (p=0.022), especially for metastatic BCs.
Conclusion
Clinical NGS provided multifaceted benefits, deepening our understanding of the disease, improving diagnostic precision, and paving the way for targeted therapies. The concrete advantages of FCP highlight the importance of multi-gene testing for BC, especially for metastatic conditions.
6.Harnessing Institutionally Developed Clinical Targeted Sequencing to Improve Patient Survival in Breast Cancer: A Seven-Year Experience
Jiwon KOH ; Jinyong KIM ; Go-Un WOO ; Hanbaek YI ; So Yean KWON ; Jeongmin SEO ; Jeong Mo BAE ; Jung Ho KIM ; Jae Kyung WON ; Han Suk RYU ; Yoon Kyung JEON ; Dae-Won LEE ; Miso KIM ; Tae-Yong KIM ; Kyung-Hun LEE ; Tae-You KIM ; Jee-Soo LEE ; Moon-Woo SEONG ; Sheehyun KIM ; Sungyoung LEE ; Hongseok YUN ; Myung Geun SONG ; Jaeyong CHOI ; Jong-Il KIM ; Seock-Ah IM
Cancer Research and Treatment 2025;57(2):443-456
Purpose:
Considering the high disease burden and unique features of Asian patients with breast cancer (BC), it is essential to have a comprehensive view of genetic characteristics in this population. An institutional targeted sequencing platform was developed through the Korea Research-Driven Hospitals project and was incorporated into clinical practice. This study explores the use of targeted next-generation sequencing (NGS) and its outcomes in patients with advanced/metastatic BC in the real world.
Materials and Methods:
We reviewed the results of NGS tests administered to BC patients using a customized sequencing platform—FiRST Cancer Panel (FCP)—over 7 years. We systematically described clinical translation of FCP for precise diagnostics, personalized therapeutic strategies, and unraveling disease pathogenesis.
Results:
NGS tests were conducted on 548 samples from 522 patients with BC. Ninety-seven point six percentage of tested samples harbored at least one pathogenic alteration. The common alterations included mutations in TP53 (56.2%), PIK3CA (31.2%), GATA3 (13.8%), BRCA2 (10.2%), and amplifications of CCND1 (10.8%), FGF19 (10.0%), and ERBB2 (9.5%). NGS analysis of ERBB2 amplification correlated well with human epidermal growth factor receptor 2 immunohistochemistry and in situ hybridization. RNA panel analyses found potentially actionable and prognostic fusion genes. FCP effectively screened for potentially germline pathogenic/likely pathogenic mutation. Ten point three percent of BC patients received matched therapy guided by NGS, resulting in a significant overall survival advantage (p=0.022), especially for metastatic BCs.
Conclusion
Clinical NGS provided multifaceted benefits, deepening our understanding of the disease, improving diagnostic precision, and paving the way for targeted therapies. The concrete advantages of FCP highlight the importance of multi-gene testing for BC, especially for metastatic conditions.
7.The effect of an internet of things-based mobile health management application for older adults depending on user engagement in South Korea: a secondary analysis of a quasi-experimental study
Jeongeun CHOI ; Hyeonmi CHO ; Jo Woon SEOK ; Hyangkyu LEE
Journal of Korean Biological Nursing Science 2025;27(1):38-48
This study aimed to evaluate the effect of the TouchCare system, a digital health management system utilizing the internet of things (IoT), based on the usage levels of older adults. Methods: This is a secondary analysis of data from a quasi-experimental study examining the effects of an IoT-based digital healthcare system. Participants were equipped with the TouchCare application, a touch-tag, and context-aware artificial intelligence. Data on cognitive function, frailty, depressive symptoms, nutritional status, and fall efficacy were collected at baseline and after six months of using the system. The participants were divided into a high-engagement group (n = 22) and a low-engagement group (n = 24) based on how many days they used the application during the study. We used descriptive statistics, the paired t-test, the independent-samples t-test, and two-way mixed analysis of variance. Results: In total, 46 participants completed the evaluations (mean age, 76.6 years). Two-way mixed analysis of variance revealed no significant group-by-time interaction for cognitive function (p = .184), frailty (p = .338), depressive symptoms (p = .543), and nutritional status (p = .589). There was no significant difference in fall efficacy between the two groups (p = .091). The high-engagement group exhibited significant improvements in visuospatial and executive functions on the Montreal Cognitive Assessment (p = .029). Conclusion: The IoT-based mobile health management application demonstrated benefits in improving cognitive health among older adults. The findings suggest that active engagement with healthcare technology can positively affect health in this population, emphasizing the need for continuous support from nurses as health providers.
8.Development of a Korean version of the Frailty Model with a Holistic Perspective: A Delphi Study
Ju Hee LEE ; Gwang Suk KIM ; Sanghee KIM ; Eunyoung KIM ; Layoung KIM ; Jee-Hye YOO
Journal of Korean Academy of Fundamental Nursing 2025;32(2):220-232
Purpose:
This study aimed to develop a Korean version of the frailty model that reflects a holistic perspective. There were three phases of the study: a literature review, a two-round Delphi study, and a public hearing.
Methods:
The model was developed based on the middle-range theory generation approach proposed by Roy. A literature search was conducted, and a review of 36 studies on frailty involving Koreans led to the development of an initial frailty model. A two-round Delphi study was then conducted with nine experts to evaluate the appropriateness of the model. The revised model was presented at a public hearing to achieve consensus. Based on feedback indicating the need for improved visualization, a finalized diagrammatic model was developed.
Results:
The final frailty model comprised four domains, seven subdomains, and 30 items. It included specific items reflecting the distinctive characteristics of Korean culture, such as relationships with adult children (filial piety), nutritional status (consumption of red meat), and type of residential building.
Conclusion
The final frailty model provides a comprehensive perspective on the factors contributing to frailty, their interactions, and the potential interventions that healthcare providers can implement to prevent frailty.
9.The effect of an internet of things-based mobile health management application for older adults depending on user engagement in South Korea: a secondary analysis of a quasi-experimental study
Jeongeun CHOI ; Hyeonmi CHO ; Jo Woon SEOK ; Hyangkyu LEE
Journal of Korean Biological Nursing Science 2025;27(1):38-48
This study aimed to evaluate the effect of the TouchCare system, a digital health management system utilizing the internet of things (IoT), based on the usage levels of older adults. Methods: This is a secondary analysis of data from a quasi-experimental study examining the effects of an IoT-based digital healthcare system. Participants were equipped with the TouchCare application, a touch-tag, and context-aware artificial intelligence. Data on cognitive function, frailty, depressive symptoms, nutritional status, and fall efficacy were collected at baseline and after six months of using the system. The participants were divided into a high-engagement group (n = 22) and a low-engagement group (n = 24) based on how many days they used the application during the study. We used descriptive statistics, the paired t-test, the independent-samples t-test, and two-way mixed analysis of variance. Results: In total, 46 participants completed the evaluations (mean age, 76.6 years). Two-way mixed analysis of variance revealed no significant group-by-time interaction for cognitive function (p = .184), frailty (p = .338), depressive symptoms (p = .543), and nutritional status (p = .589). There was no significant difference in fall efficacy between the two groups (p = .091). The high-engagement group exhibited significant improvements in visuospatial and executive functions on the Montreal Cognitive Assessment (p = .029). Conclusion: The IoT-based mobile health management application demonstrated benefits in improving cognitive health among older adults. The findings suggest that active engagement with healthcare technology can positively affect health in this population, emphasizing the need for continuous support from nurses as health providers.
10.The effect of an internet of things-based mobile health management application for older adults depending on user engagement in South Korea: a secondary analysis of a quasi-experimental study
Jeongeun CHOI ; Hyeonmi CHO ; Jo Woon SEOK ; Hyangkyu LEE
Journal of Korean Biological Nursing Science 2025;27(1):38-48
This study aimed to evaluate the effect of the TouchCare system, a digital health management system utilizing the internet of things (IoT), based on the usage levels of older adults. Methods: This is a secondary analysis of data from a quasi-experimental study examining the effects of an IoT-based digital healthcare system. Participants were equipped with the TouchCare application, a touch-tag, and context-aware artificial intelligence. Data on cognitive function, frailty, depressive symptoms, nutritional status, and fall efficacy were collected at baseline and after six months of using the system. The participants were divided into a high-engagement group (n = 22) and a low-engagement group (n = 24) based on how many days they used the application during the study. We used descriptive statistics, the paired t-test, the independent-samples t-test, and two-way mixed analysis of variance. Results: In total, 46 participants completed the evaluations (mean age, 76.6 years). Two-way mixed analysis of variance revealed no significant group-by-time interaction for cognitive function (p = .184), frailty (p = .338), depressive symptoms (p = .543), and nutritional status (p = .589). There was no significant difference in fall efficacy between the two groups (p = .091). The high-engagement group exhibited significant improvements in visuospatial and executive functions on the Montreal Cognitive Assessment (p = .029). Conclusion: The IoT-based mobile health management application demonstrated benefits in improving cognitive health among older adults. The findings suggest that active engagement with healthcare technology can positively affect health in this population, emphasizing the need for continuous support from nurses as health providers.

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