Objective To investigate the application value of ankle-brachial index(ABI)combined with Wagner scale in the prognosis assessment in patients with diabetic foot(DF).Methods A total of 120 patients with DF were enrolled in this study from in our hospital from June 2020 to December 2021.All the patients were divided into good prognosis group(n=92)and poor prognosis group(n=28)according to the prognosis after 6 months.The ABI and related clinical indicators were compared between the two groups.Logistic regression analysis and receiver operating characteristic(ROC)curve were used to analyze the prognostic value of each index in patients with DF.Results The DF duration,HbA1c,white blood cell count,Wagner grade 3 to 5,antibiotic type≥3,defibration times≥3 were higher in the poor prognosis group than in the good prognosis group(P<0.05),while the albumin,TG,ABI,hemoglobin and revasectomy rates were lower in the poor prognosis group than in the good prognosis group(P<0.05).Logistic regression analysis showed that HbA1c(OR 3.232,95%CI 1.063～9.830),ABI(OR 0.150,95%CI 0.038～0.588),Wagner grading(OR 5.032,95%CI 1.258～20.128)were the prognostic factor for patients with DF.The driving equation was established:Logit(P)=1.908×Wagner grading-1.978×ABI-1.945.ROC curve analysis showed that the area under the curve(0.897)of driving equation was higher than ABI(0.754)and Wagner grading(0.810)(P<0.05)in predicting poor prognosis in patients with DF.Conclusions ABI and Wagner grading are both factors affecting the poor prognosis of patients with DF,and ABI combined with Wagner grading is more effective in predicting the prognosis of patients with DF.

Objective To investigate the application value of ankle-brachial index(ABI)combined with Wagner scale in the prognosis assessment in patients with diabetic foot(DF).Methods A total of 120 patients with DF were enrolled in this study from in our hospital from June 2020 to December 2021.All the patients were divided into good prognosis group(n=92)and poor prognosis group(n=28)according to the prognosis after 6 months.The ABI and related clinical indicators were compared between the two groups.Logistic regression analysis and receiver operating characteristic(ROC)curve were used to analyze the prognostic value of each index in patients with DF.Results The DF duration,HbA1c,white blood cell count,Wagner grade 3 to 5,antibiotic type≥3,defibration times≥3 were higher in the poor prognosis group than in the good prognosis group(P<0.05),while the albumin,TG,ABI,hemoglobin and revasectomy rates were lower in the poor prognosis group than in the good prognosis group(P<0.05).Logistic regression analysis showed that HbA1c(OR 3.232,95%CI 1.063～9.830),ABI(OR 0.150,95%CI 0.038～0.588),Wagner grading(OR 5.032,95%CI 1.258～20.128)were the prognostic factor for patients with DF.The driving equation was established:Logit(P)=1.908×Wagner grading-1.978×ABI-1.945.ROC curve analysis showed that the area under the curve(0.897)of driving equation was higher than ABI(0.754)and Wagner grading(0.810)(P<0.05)in predicting poor prognosis in patients with DF.Conclusions ABI and Wagner grading are both factors affecting the poor prognosis of patients with DF,and ABI combined with Wagner grading is more effective in predicting the prognosis of patients with DF.

Objective:To analyze independent influencing factors of surgical textbook outcome (TO) in patients with gallbladder carcinoma, and to establish a nomogram for predicting TO and evaluated the predictive ability.Methods:Patients with gallbladder carcinoma who underwent surgery in Department of Hepatobiliary and Pancreatic Surgery at Dongfang Hospital Affiliated to Shanghai Tongji University and Department of Biliary Tract Surgery Ⅰ, Third Affiliated Hospital of Naval Medical University (Shanghai Eastern Hepatobiliary Surgery Hospital) from January 2013 to December 2018 were included and the clinical features were retrospectively analyzed. A total of 232 patients were included, including 114 males and 118 females, aged (61.0±9.8) years. According to whether TO reached or not, they were divided into TO group ( n=86) and non-TO group ( n=146). Univariate and multivariate logistic regression were used to analyze the independent influencing factors of TO. The predictive nomogram model of TO was constructed. The receiver operating characteristic (ROC) curve was drawn to evaluate the predictive ability of the model, and the consistency of the predictive model was evaluated by the consistency curve graph and the Hosmer-Lemeshow test. Results:The 1-year and 3-years cumulative survival rates of patients with gallbladder carcinoma in the TO group (86.0% and 62.8%) were better than those in the non-TO group (46.6% and 27.3%), and the difference was statistically significant (χ 2=60.74, P<0.001). In multivariate analysis, higher T stage ( OR=0.16, 95% CI: 0.03-0.79, P<0.001) and cervical gallbladder cancer ( OR=0.14, 95% CI: 0.02-0.94, P=0.004) had the greatest negative association with a TO, and the higher the degree of tumor differentiation ( OR=7.08, 95% CI: 1.34-37.56, P=0.001), the easier it is to achieve TO. The ROC curve showed that the area under the curve of the predictive model was 0.84 (95% CI: 0.79-0.90), suggesting that the model had good predictive performance. A nomogram to assess the probability of TO was developed and had good accuracy in both the consistency curve and Hosmer-Lemeshow test (χ 2=5.77, P=0.673). Conclusion:Tumor T stage, tumor differentiation degree and tumor location are independent influencing factors for achieving TO in patients with gallbladder carcinoma after surgery. The nomogram model constructed according to the above conclusions could accurately predict the probability of reaching TO.