1.Clinical Efficacy of Chaixia Sanjie Formula in Treating Pulmonary Nodules
Qinyan HONG ; Mingsheng LV ; Xinyi ZHANG
Journal of Medical Research 2025;54(7):123-128,151
Objective To retrospectively analyze the clinical efficacy of the Chaixia Sanjie formula in treating pulmonary nodules.Methods Retrospective collection of 107 patients with pulmonary nodules and liver-qi stagnation syndrome who received the Chaixia Sanjie formula for 3months or more at Dongzhimen Hospital,Beijing University of Chinese Medicine,from January 2021 to June 2024 as the observation group.Another 107 patients with pulmonary nodules and liver-qi stagnation syndrome who did not receive traditional Chi-nese medicine(TCM)intervention during the same period were selected as the control group.Basic information,TCM syndromes,and the diameters of pulmonary nodules on chest HRCT at the first and last visit were collected.Changes in nodule diameter,TCM syndrome scores,and TCM therapeutic efficacy were compared between the two groups.Results Compared with the control group,the nodule di-ameter in the observation group was smaller and the difference was statistically significant(P<0.05),and the proportion of nodule disap-pearance or reduction was higher in the observation group than in the control group,and the difference was statistically significant(P<0.05).At the final diagnosis,the observation group showed a decrease in traditional Chinese medicine syndrome scores,including chest fullness,emotional instability,belching and bloating,rib pain,foreign body sensation in the throat,bitter mouth,lack of appetite,irreg-ular bowel movements,and sleep disorders,compared to the initial diagnosis and the control group,with statistical significance(P<0.05).The effective rate of TCM syndrome improvement in the observation group was 88.8%.Conclusion The Chaixia Sanjie formula can reduce the diameter of pulmonary nodules to some extent and improve TCM syndromes in patients with pulmonary nodules.
2.Clinical Efficacy of Chaixia Sanjie Formula in Treating Pulmonary Nodules
Qinyan HONG ; Mingsheng LV ; Xinyi ZHANG
Journal of Medical Research 2025;54(7):123-128,151
Objective To retrospectively analyze the clinical efficacy of the Chaixia Sanjie formula in treating pulmonary nodules.Methods Retrospective collection of 107 patients with pulmonary nodules and liver-qi stagnation syndrome who received the Chaixia Sanjie formula for 3months or more at Dongzhimen Hospital,Beijing University of Chinese Medicine,from January 2021 to June 2024 as the observation group.Another 107 patients with pulmonary nodules and liver-qi stagnation syndrome who did not receive traditional Chi-nese medicine(TCM)intervention during the same period were selected as the control group.Basic information,TCM syndromes,and the diameters of pulmonary nodules on chest HRCT at the first and last visit were collected.Changes in nodule diameter,TCM syndrome scores,and TCM therapeutic efficacy were compared between the two groups.Results Compared with the control group,the nodule di-ameter in the observation group was smaller and the difference was statistically significant(P<0.05),and the proportion of nodule disap-pearance or reduction was higher in the observation group than in the control group,and the difference was statistically significant(P<0.05).At the final diagnosis,the observation group showed a decrease in traditional Chinese medicine syndrome scores,including chest fullness,emotional instability,belching and bloating,rib pain,foreign body sensation in the throat,bitter mouth,lack of appetite,irreg-ular bowel movements,and sleep disorders,compared to the initial diagnosis and the control group,with statistical significance(P<0.05).The effective rate of TCM syndrome improvement in the observation group was 88.8%.Conclusion The Chaixia Sanjie formula can reduce the diameter of pulmonary nodules to some extent and improve TCM syndromes in patients with pulmonary nodules.
3.Analysis of influencing factors on hospitalization costs of elderly osteoporosis hip fracture
Hong WANG ; Mingsheng LI ; Yanwei LV ; Hailing CHEN ; Quan ZHANG ; Wei LI ; Lili DENG
Chinese Journal of Geriatrics 2012;31(11):1010-1014
Objective To analyze the influencing factors on hospitalization costs of osteoporosis hip fracture in elderly patients.Methods The hospitalization expenses of patients with osteoporotic hip fracture and influencing factors were analyzed by single factor analysis of variance and multiple regression analysis method in Beijing Ji Shuitan Hospital from 2009 July to 2010 December.Results Among 565 patients who underwent operation treatment,hospitalization costs of femoral neck fracture was (42 127±20 821) yuan,wherein the treatment fee was (27 283± 14 959) yuan,other expenses (expenses for medicine,examination and chemical examination) were (14 844 ± 8717) yuan.The above values of intertrochanteric fracture were (52 965± 15 901) yuan,(36 872±11 763) yuan and (16 093±7793) yuan,respectively.Treatment fee occupied 65% of hospitalization expenses.Multivariate regression analysis of influencing factors of costs intertrochanteric revealed that femoral neck fractures hip arthroplasty,femoral intertrochanteric fracture,venous thrombosis of the lower extremity,and albumin infusion in perioperative period were correlated firmly with the increased hospitalization expenses and treatment expenses (P<0.001).Comorbidities such as diabetes and anemia,perioperative complication such as delirium,cardiac disease,pulmonary embolism,pulmonary infection were related to the other higher expenses (P<0.05).The longer of hospital stay resulted in higher cost of hospitalization (P < 0.001).Conclusions Comorbidities and preoperative complications can increase other expenses.Osteoporotie hip fracture,with a high hospitalization cost,is a heavy economy burden.It is important to emphasize the disease prevention of both osteoporosis and aging chronic illness.

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