The development of artificial intelligence(AI)technology has promoted major changes in the field of immunology innovation and teaching reform.Traditional teaching classrooms are developing towards digital and intelligent teaching models.In order to improve high-quality education,cultivate AI thinking and comprehensive ability of graduate students,optimize current situations of traditional large classes and diversified characteristics of student,the AI technology is used to analyze the learning situation of students before class.Next,differentiated intelligence allocates digital learning materials according to the results of pre-class survey analysis,adopts"Research on scientific literature-based flipped classroom"teaching methods,carries out differentiated assessment methods,and finally the personalized teaching mode of doctoral students is implemented.This teaching strategy of deep integration of artificial intelligence and personalization can provide theoretical support and practical guidance for the subsequent reform and innovation in the immunology classroom and meet the needs of personalized training for PhD doctoral talents.

The development of artificial intelligence(AI)technology has promoted major changes in the field of immunology innovation and teaching reform.Traditional teaching classrooms are developing towards digital and intelligent teaching models.In order to improve high-quality education,cultivate AI thinking and comprehensive ability of graduate students,optimize current situations of traditional large classes and diversified characteristics of student,the AI technology is used to analyze the learning situation of students before class.Next,differentiated intelligence allocates digital learning materials according to the results of pre-class survey analysis,adopts"Research on scientific literature-based flipped classroom"teaching methods,carries out differentiated assessment methods,and finally the personalized teaching mode of doctoral students is implemented.This teaching strategy of deep integration of artificial intelligence and personalization can provide theoretical support and practical guidance for the subsequent reform and innovation in the immunology classroom and meet the needs of personalized training for PhD doctoral talents.

Vaccines for immunization programs play a pivotal role in the prevention and control of infectious diseases in China. Since the implementation of the Expanded Program on Immunization in 2007, a total of 15 vaccines have been used in the national immunization program, which can prevent 15 kinds of diseases. The development of vaccines in China′s immunization program in the past decade is analyzed in terms of variety, quantity, production enterprise, quality standard, and supervision system. The results show that the average dose of vaccines for China′s immunization planning is about 570 million doses per year from 2011 to 2020. The overall development of the vaccine industry for immunization planning is stable, and there are between one to five manufacturers for each type of vaccine mainly relying on domestic production. Vaccine quality standards have been continuously improved and are basically consistent with international standards. The vaccine supervision system has been continuously completed and covered the entire process of research and development, production and distribution.

Vaccines for immunization programs play a pivotal role in the prevention and control of infectious diseases in China. Since the implementation of the Expanded Program on Immunization in 2007, a total of 15 vaccines have been used in the national immunization program, which can prevent 15 kinds of diseases. The development of vaccines in China′s immunization program in the past decade is analyzed in terms of variety, quantity, production enterprise, quality standard, and supervision system. The results show that the average dose of vaccines for China′s immunization planning is about 570 million doses per year from 2011 to 2020. The overall development of the vaccine industry for immunization planning is stable, and there are between one to five manufacturers for each type of vaccine mainly relying on domestic production. Vaccine quality standards have been continuously improved and are basically consistent with international standards. The vaccine supervision system has been continuously completed and covered the entire process of research and development, production and distribution.

OBJECTIVE： To provide reference for the formulation of Chinese pharmacy accreditation criteria. METHODS： By literature method， the evolution of American Association of Colleges of Pharmacy （AACP） membership criteria were described， and the development of Chinese pharmacy accreditation criteria were also described. RESULTS & CONCLUSIONS： The membership criteria of AACP are characterized by attaching importance to investigation and research， highlighting goal orientation， keeping pace with the times， and strengthening process supervision. The pharmacy accreditation criteria in China was mainly promoted by the competent education department from top to bottom， which has the characteristics of government dominance， decision-making authority and caution. Compared with the American pharmacy accreditation criteria， there were some problems in our country， such as slow response to professional changes， poor flexibility of system and insufficient reflection of overall professional development. Although there is no real similar organization in China， the development of AAPA membership criteria can be used for reference in China， such as the close relationship between pharmacy industry associations and accreditation organizations， strengthening the construction of pharmaceutical accreditation organizations to maintain their independence and specialty， pharmacy standards dynamic adjustment， etc.

OBJECTIVE:To improve the quality of talent training of clinical pharmacy.METHODS:The present situation of teaching team in clinical pharmacy practice base were summarized to analyze the existing problems.The future development countermeasures were put forward in respects of thought,ability,system.RESULTS & CONCLUSIONS:The post cognition of clinical pharmacy teaching team can be strengthened by strengthening the awareness of clinical pharmacy teaching team,clarifying the responsibilities of clinical pharmacy teaching team and improving the curriculum system of teaching,The comprehensive ability and level of clinical pharmacy teaching team can be improved by improving the professional knowledge structure of clinical pharmacy teaching team,promoting the theoretical level and ability of teaching and strengthening the construction of teachers' ethics.The level of teaching team in clinical pharmacy practice base can be enhanced by constructing collaborative incentive and competition mechanism between universities and hospitals.It not only can guarantee the quality and effect of teaching,but also can adapt to the reform and development of higher education and public hospitals,improve the level of medical services.

Objective To explore levels of cytokine and 25-hydroxyvitamin D in the blood of infants with rotavirus enteritis and their clinical significance.Methods Sixty-eight infants with rotavirus enteritis were recruited as the research group, while 56 healthy infants who underwent normal physical checks were assigned as the control group.Fasting venous blood samples were collected for the detection of cytokine and 25-hydroxyvitamin D levels by RP-HPLC method.Results The levels of IL-2, IL-6, TNF-αin the in-fants of the research group were significantly higher than those of the infants of the control group (P<0.01).The level of 25-hydroxyvi-tamin D of the study group was obviously lower than that of the control group (P<0.05).Conclusion The elevated levels of IL-2, IL-6, TNF-αin the infants with rotavirus enteritis were associated with the decreased level of 25-hydroxyvitamin D.