Objective:To investigate the application of virtual simulation-based teaching-examination linkage mode based on aneSIM anesthesia simulation system and NW13 difficult airway management model in improving the ability of anesthesia crisis resource management among trainees receiving standardized residency training.Methods:A total of 236 trainees (189 trainees with non-anesthesia majors and 47 with anesthesia majors) who received standardized residency training in Department of Anesthesiology in 2021 were selected as control group, and 234 resident trainees (184 trainees with non-anesthesia majors and 50 with anesthesia majors) in 2022 were selected as observation group. The trainees in the control group received traditional theoretical teaching, and those in the observation group received teaching with the aneSIM system. The trainees in both groups received two sessions of online theoretical assessment through the QR code in Bangboss Application, as well as situational simulation training and assessment using the NW13 difficult airway management model. SPSS 26.0 was used to perform the t-test and the chi-square test. Results:Compared with the control group, the observation group had a significantly higher score of the second theoretical assessment, significantly better degree of anxiety and score of simulation assessment, and significantly better knowledge mastery and ability improvement ( t=7.15, 14.31, 3.90, 6.22, 4.23, 3.04, all P<0.05). Compared with the control group in terms of the resident trainees with non-anesthesia majors, the observation group had a significantly higher score of the second theoretical assessment, significantly better degree of anxiety and score of simulation assessment, a significantly higher degree of satisfaction with teaching, and significantly better knowledge mastery and ability improvement ( t=7.77, 5.43, 3.09, 5.26, 3.82, 2.19, all P<0.05). Compared with the control group in terms of the resident trainees with anesthesia majors, the observation group had a significantly higher score of simulation assessment, a significantly higher degree of satisfaction with teaching, and significantly better knowledge mastery and ability improvement ( t=2.60, 3.56, 2.01, 2.48, P=0.011, 0.001, 0.047, 0.015). Conclusions:The mode of virtual simulation-based teaching-examination linkage based on the aneSIM anesthesia simulation system and NW13 difficult airway management model can examine and improve the abilities for difficult airway management and operation among resident trainees, especially those with non-anesthesia majors, thereby showing its application value in the teaching of anesthesia crisis resource management.

Objective:To investigate the application of virtual simulation-based teaching-examination linkage mode based on aneSIM anesthesia simulation system and NW13 difficult airway management model in improving the ability of anesthesia crisis resource management among trainees receiving standardized residency training.Methods:A total of 236 trainees (189 trainees with non-anesthesia majors and 47 with anesthesia majors) who received standardized residency training in Department of Anesthesiology in 2021 were selected as control group, and 234 resident trainees (184 trainees with non-anesthesia majors and 50 with anesthesia majors) in 2022 were selected as observation group. The trainees in the control group received traditional theoretical teaching, and those in the observation group received teaching with the aneSIM system. The trainees in both groups received two sessions of online theoretical assessment through the QR code in Bangboss Application, as well as situational simulation training and assessment using the NW13 difficult airway management model. SPSS 26.0 was used to perform the t-test and the chi-square test. Results:Compared with the control group, the observation group had a significantly higher score of the second theoretical assessment, significantly better degree of anxiety and score of simulation assessment, and significantly better knowledge mastery and ability improvement ( t=7.15, 14.31, 3.90, 6.22, 4.23, 3.04, all P<0.05). Compared with the control group in terms of the resident trainees with non-anesthesia majors, the observation group had a significantly higher score of the second theoretical assessment, significantly better degree of anxiety and score of simulation assessment, a significantly higher degree of satisfaction with teaching, and significantly better knowledge mastery and ability improvement ( t=7.77, 5.43, 3.09, 5.26, 3.82, 2.19, all P<0.05). Compared with the control group in terms of the resident trainees with anesthesia majors, the observation group had a significantly higher score of simulation assessment, a significantly higher degree of satisfaction with teaching, and significantly better knowledge mastery and ability improvement ( t=2.60, 3.56, 2.01, 2.48, P=0.011, 0.001, 0.047, 0.015). Conclusions:The mode of virtual simulation-based teaching-examination linkage based on the aneSIM anesthesia simulation system and NW13 difficult airway management model can examine and improve the abilities for difficult airway management and operation among resident trainees, especially those with non-anesthesia majors, thereby showing its application value in the teaching of anesthesia crisis resource management.

Adopting the cell model of multilayer spherical symmetry and the circuit analysis, the present paper gives the calculated results of the voltages on each of several parts of malignant Tonsillar B-cells and Jurkat T lymphocytes when the first-order Gaussian pulses at different central frequency apposed on them. The relationship between the central frequency and the transmembrane voltages of plasma membrane is also given. The optimum frequency causing electroporation in nuclear envelope is given as well. The paper discusses the reasons of electroporation in membrane and DNA degradation in nuclear. The work provides a reference for usage of transient bipolar electric pulses in cancer treatment.
Apoptosis ; radiation effects ; B-Lymphocytes ; cytology ; radiation effects ; Cell Line, Tumor ; Cell Membrane ; physiology ; Electromagnetic Fields ; Electroporation ; methods ; Humans ; Jurkat Cells ; Nuclear Envelope ; pathology ; radiation effects

Nuclear envelope voltages of T cells were analyzed with a lumped circuitry for cells in combination with frequency domain power density of Gaussian pulses and monocycle pulses. According to the differences in geometric and electric parameters between normal and malignant T cells, circuitry analysis was performed. Theoretical evaluations indicated that apoptosis of malignant T cells was of feasibility, which could be applied in cancer therapy. The evaluations were in accord with the published experimental findings.
Animals ; Apoptosis ; radiation effects ; Electric Stimulation ; Electromagnetic Fields ; Electrophysiology ; Fourier Analysis ; Humans ; Jurkat Cells ; Nuclear Envelope ; pathology ; radiation effects ; T-Lymphocytes ; cytology ; radiation effects