Objective:To evaluate the clinical efficacy of heat-sensitive moxibustion combined with kneading and massage manipulation at pain points in treating patients with lumbar disc herniation (LDH) and chronic low back pain (LBP).Methods:Randomized controlled trial. A total of 91 patients with LDH and LBP who were admitted to Lu'an Hospital of Traditional Chinese Medicine from January 2020 to December 2022 were selected as the observation subjects. They were divided into the experimental group (46 cases) and the control group (45 cases) by random number table method. The control group was treated with conventional massage manipulation, while the experimental group was treated with heat-sensitive moxibustion combined with kneading and massage manipulation at pain points. Both groups received 4 weeks of continuous treatment. The degree of lumbar pain was evaluated with the Visual Analogue Scale (VAS), and the degree of lumbar dysfunction was evaluated with modified Oswestry Disability Index (ODI). Plasma viscosity, hematocrit, whole blood low shear viscosity and whole blood high shear viscosity were measured using a blood rheometer. Clinical efficacy was evaluated.Results:The total clinical effective rates in the experimental group and the control group were 93.48% (43/46) and 77.78% (35/45), with a statistical significance between groups ( χ2=4.58, P=0.032). After treatment, the VAS score [(3.81±0.74) vs. (4.29±0.85), t=2.88] and ODI score [(8.79±2.65) vs. (11.25±3.74), t=3.63] of the experimental group were lower than those of the control group ( P<0.01). Plasma viscosity [(1.35±0.06) mPa?s vs. (1.41±0.08) mPa?s, t=4.05], hematocrit [(37.46±2.38)% vs. (40.15±2.94)%, t=4.80], whole blood low shear viscosity [(7.41±1.53) mPa?s vs. (8.64±1.72) mPa?s, t=3.61] and whole blood high shear viscosity [(3.81±0.29) mPa?s vs. (4.07±0.31) mPa?s, t=4.13] were lower than those in the control group ( P<0.01). Conclusion:Heat-sensitive moxibustion combined with kneading and massage manipulation at pain points can effectively relieve LBP in patients with LDH and chronic LBP, improve lumbar dysfunction and hemodynamic status, and enhance clinical efficacy.

Objective Based on the dummy model, to study the relationship between different backrest angles and neck injuries under the effect of horizontal negative acceleration (-Gx ). Methods The dummy model was fixed on the base of the acceleration platform facing the orbital direction, and the backrest angle was set at 17°, 22°, 30°, respectively. Each experimental group performed 10 repeated tests according to the same acceleration curve, differences between the upper and lower acceleration of the cervical spine under the same -Gx conditions were compared, and the neck injury criteria (NIC) was calculated and compared through curve fitting. Results The time-acceleration curves of the upper and lower cervical spine in the anteroposterior and vertical directions had the same shape with peak differences. In the anteroposterior direction (X-axis), the acceleration peak of the 22° backrest angle experimental group was slightly higher than that of 17° and 30° backrest angle experimental groups, but in the vertical direction (Z-axis), the acceleration peak of the 22° backrest experimental group was lower than that of 17° and 30° backrest angle experimental groups. In the anteroposterior and vertical directions, the NICmax measured by 22° backrest angle experimental group was relatively smaller, NICmax measured by 30°backrest angle experimental group was in the middle, and NICmax measured by 30° backrest angle experimental group was relatively larger. Conclusions There was a nonlinear relationship between the backrest angle and theneck injury. The neck injury of the dummy model with the backrest angle of 22° was smallest under the effect of-Gx in this experiment.

Objective To compare the differences of neck injury risks for different mummies during arrested landing on naval vessels. Methods Based on the established dynamic model of dummy-belt-seat systems and mechanical model of head-neck, with the acceleration curve at seat base during typical arrested landing reported in the literature as the input, numerical simulation was conducted to test the validity of the model, and the axial force, shear force， bending moment of typical joints in dummy neck during arrested landing were obtained. Results The injury index Nkm of 95 percentile dummy was higher than that of 5 percentile dummy. The injury index Nij of the dummy’s upper and lower cervical spine was smaller than 0.2, meanwhile the Nkm was around 0.65. Conclusions During arrested landing, human neck was much easier to get hurt due to the shear force. The research findings can provide data support for evaluating neck injury risks of pilots with different sizes during typical arrested landing process.

Objective To investigate the influences of mechanical crush induced by the sustained-Gxacceleration during arrested landing process on pilot's heart and lung in order to evaluate the risks of injury . Methods A high geometric accuracy ,rigidity-viscoelasticity finite element model of human heart ,lung and chest bones were built based on anatomical data and the material properties of different tissues obtained from published literature .The finite element dynamic explicit was conducted for analyzing the responses of the human heart and lung during typical arrested landing process . Results The simulation study demonstrates that -Gxwould generate impact stress on human heart and lungs and cause the relative displacement between heart ,lungs and chest bones .It presents the-Gxinduced mechanical crush influence on the aircraft carrier pilot during arrested landing .

Objective To investigate the influences of mechanical crush induced by the sustained-Gxacceleration during arrested landing process on pilot's heart and lung in order to evaluate the risks of injury . Methods A high geometric accuracy ,rigidity-viscoelasticity finite element model of human heart ,lung and chest bones were built based on anatomical data and the material properties of different tissues obtained from published literature .The finite element dynamic explicit was conducted for analyzing the responses of the human heart and lung during typical arrested landing process . Results The simulation study demonstrates that -Gxwould generate impact stress on human heart and lungs and cause the relative displacement between heart ,lungs and chest bones .It presents the-Gxinduced mechanical crush influence on the aircraft carrier pilot during arrested landing .

Objective To review the conception and tests of stereovision and its application in clinical medicine and physical examinations for military pilots at home and abroad so as to provide theory basis of improving stereovision tests applying to military pilots.Literature resource and selection The related articles published at home and abroad.Literature quotation Forty published references were cited.Literature synthesis The concept,classification and examination tests of stereovision were reviewed.Tests for reading distance stereovision mainly included:Lang stereotest,Yanks randot stereotests,Frisby stereotest,Randot stereotest,TNO stereotest and Titmus stereotest.The Howard-Dolman's apparatus,synoptiscope,Distance Randot test and Frisby-Davis 2 distance stereotest were applied to long distance stereovision examination.Stereovision tests played a key role in the detection and effectiveness evaluation of various ophthalmological diseases,such as strabismus,amplyopia,ametropia,etc..Besides,it was also applied in military medicine like selection and conventional physical examinations for military pilots at home and abroad.Conclusions The polarizing/red-green glasses that subjects wearing in most stereovision tests may disturb the brightness and definition of the stereographs,and further the clinical determination..More effective stereovision tests should be developed with specification of physical examination in Chinese military pilot to provide powerful support for flight safety.

Objective To review the conception and tests of stereovision and its application in clinical medicine and physical examinations for military pilots at home and abroad so as to provide theory basis of improving stereovision tests applying to military pilots.Literature resource and selection The related articles published at home and abroad.Literature quotation Forty published references were cited.Literature synthesis The concept,classification and examination tests of stereovision were reviewed.Tests for reading distance stereovision mainly included:Lang stereotest,Yanks randot stereotests,Frisby stereotest,Randot stereotest,TNO stereotest and Titmus stereotest.The Howard-Dolman's apparatus,synoptiscope,Distance Randot test and Frisby-Davis 2 distance stereotest were applied to long distance stereovision examination.Stereovision tests played a key role in the detection and effectiveness evaluation of various ophthalmological diseases,such as strabismus,amplyopia,ametropia,etc..Besides,it was also applied in military medicine like selection and conventional physical examinations for military pilots at home and abroad.Conclusions The polarizing/red-green glasses that subjects wearing in most stereovision tests may disturb the brightness and definition of the stereographs,and further the clinical determination..More effective stereovision tests should be developed with specification of physical examination in Chinese military pilot to provide powerful support for flight safety.

Objective To investigate the correlation between atorvastatin inhibiting Interleukin-1β(IL-1β) expression and peroxisome proliferator activated receptor β/δ (PPARβ/δ) signal channel in myocyte of aging rat. Methods Primary culture of myocyte were got from aging rat. Myocyte were divided into control group, DMSO group, atorvastatin group, atorvastatin plus GSK0660 group, whichwere treated respectively by Cell culture medium, dimethyl sulfoxide (DMSO), atorvastatin, atorvastin plus GSK0660. The expression level of IL-1βmRNA and protein was evaluated by RT-PCR and Western Blot respectively. Results (1)NO difference were found between control group and DMSO group in expression level of IL-1βmRNA and protein (P>0.05);(2)The expression level of IL-1βmRNA and protein in atorvastatin group were significantly lower than those of control group (P < 0.01); (3)Both mRNA and protein expression level of IL-1βin atorvastatin plus GSK0660 group were higher than those of atorvastatin group(P<0.05 or P<0.01), but still lower than those of control group(P<0.05). Conclusions Atorvastatin down-regulate the expression of IL-1βin aging myocytes by activating PPARβ/δsignal Channel.

The wavelength of infrared rays,beyond that of red visible light in optical spectre,ranges from 0.76 to 1000.00 μm.In clinic,infrared rays include a near-infrared part(with the wavelength ranging from 0.76 to 1.5μm)and a far-infrared part(with the wavelength ranging from 1.5 to 400μm).The far-infrared rays,having a wavelength ranging from 6 to 14 μm,are critical for human health and lives.The far-infrared rays have many biological functions including extending blood capillary,increasing blood flow,enhancing metabolism and repair,accommodating organism disequilibrium,etc.The main biological effect of far-infrared rays is cell activation which can induce a senes of biochemistry and histochemistry changes of calls.With the help of far-infrared rays,human body can be in a healthy status.The main clinical applications of far-infrared rays include auxiliary diagnosis,softening inflammation and pain.tissue repair,sterilization,tumor depression,rewarming from hypothermia,and so on.Far-infrared rays play active functions on human body through caloric effects.Now they are developed to be applied in partial medical fields.The emphases of the future studies are about the effects of far-infrared rays based on molecular biology researches and about the extensive applications of far-infrared rays in medicine.

BACKGROUND: Angiotensin Ⅱ (Ang-Ⅱ) can stimulate vascular endothelial cells to excrete endothelin, a kind of potent vasoconstrictor. The content of endothelin in blood or cell culture media directly reflects the function and injured status of vascular endothelial cells. Therefore, it is significant for strengthening vascular endothelial cells to resist the injured factors. Tea polyphenols is a mainly active component of tea, and it is considered as a reagent for anti-atherosclerosis, protecting injuries of vascular endothelial cells and preventing cardiovascular diseases. OBJECTIVE: To observe the effects of tea polyphenols in different concentrations on endothelin content in vascular endothelial cells induced by Ang-Ⅱ at various time points through establishing Ang-Ⅱ-induced vascular endothelial cell injury models and further to investigate the protective effect of tea polyphenols on vascular endothelial cells. DESIGN: Observational study.SETTING: Aerospace and Diving Medical Center, Navy General Hospital of Chinese PLA.MATERIALS: The experiment was carried out in Laboratory of Aerospace and Diving Medical Center, Navy General Hospital of Chinese PLA from March to September 2005. Main materials were detailed as follows: Ang-Ⅱ (Sigma Company), tea polyphenols (Department of Tea Science, Zhejiang University) and vascular endothelial cells (human large artery vascular endothelial cell system, CBI Company, USA).METHODS: Cultured vascular endothelial cells were divided into 4 groups: ① Control group: The normal culture media was added in the isopyknic vascular endothelial cells, and 100 μL supernatant was extracted before and at 0.5, 6 and 24 hours after filling moisturized liquid. ② Ang-Ⅱ group: Cell culture media containing 10-7 mol/L Ang-Ⅱ was added in the vascular endothelial cells, and other operations were as the same as those in the control group. ③ High-concentration tea polyphenols + Ang-Ⅱ group: Cell culture media containing 50 mg/L tea polyphenols was added in the vascular endothelial cells, and other operations were as the same as those in the Ang-Ⅱ group. ④ Low-concentration tea polyphenols + Ang-Ⅱ group: Cell culture media containing 25 mg/L tea polyphenols. 100 μL supernatant was extracted before and after 0.5, 6 and 24 hours treatment in each group. Thereafter, radioimmunoassay was used to measure the content of endothelin. MAIN OUTCOME MEASURES: Content of endothelin.RESULTS: ① Content of endothelin in Ang-Ⅱ group was higher than that in the control group (P ＜ 0.01). ② At 6 and 24 hours after high-concentration tea polyphenols incubation, content of endothelin in high-concentration tea polyphenols + Ang-Ⅱ group was lower than that in Ang-Ⅱ group (P ＜ 0.01). Moreover, the content of endothelin in low-concentration tea polyphenols + Ang-Ⅱ group was lower than that in both high-concentration tea polyphenols + Ang-Ⅱ group and angiotensin Ⅱ group (P ＜ 0.01). CONCLUSION: Tea polyphenols has inhibitory effects on endothelin releasing function of vascular endothelial cells induced by Ang-Ⅱ, suggesting that tea polyphenols has protective effect on vascular endothelial cells, and the effect of low-concentration tea polyphenols is superior to that of the high-concentration one.