1.Coronary CT Angiography-Derived Fractional Flow Reserve in Asia and the United States: 2025 Status Update
Woo Jin AHN ; Maros FERENCIK ; Ming-Yen NG ; Liang ZHONG ; Mona BHATIA ; Akira KURATA ; Pannipa SUWANNASOM ; Yung-Liang WAN ; Trang Ngoc NGUYEN ; Suyon CHANG ; Sung Mok KIM ; Hwan Seok YONG ; Cherry KIM
Korean Journal of Radiology 2026;27(1):27-33
Coronary CT-derived fractional flow reserve (CT-FFR) is a noninvasive alternative to invasive FFR for assessing the hemodynamic significance of coronary artery stenosis. CT-FFR uses routinely acquired coronary CT angiography (CCTA) with artificial intelligence and computational fluid dynamics to estimate pressure gradients, thereby supporting clinical decisionmaking without procedural risk. Adoption and implementation vary widely across regions. In Asia, South Korea exclusively uses HeartMedi+, which enables rapid analysis, streamlined workflow integration, and high user satisfaction. Japan relies primarily on FFR CT, which has national reimbursement and significantly influences treatment strategies, reducing unnecessary invasive procedures. Hong Kong, Singapore, Taiwan, Thailand, and Vietnam remain in early or exploratory phases due to cost, reimbursement, and infrastructure barriers. In the United States, CT-FFR is guideline-endorsed and reimbursed, where HeartFlow is the most widely used, supported by robust clinical validation and outcome data. Despite regional variability, CTFFR offers a noninvasive solution that enhances patient management, reduces unnecessary invasive testing, and is poised for broader clinical integration as technology and validation advance.
2.SingHealth Radiology Archives pictorial essay Part 2: gastroenterology, musculoskeletal, and obstetrics and gynaecology cases.
Mark Bangwei TAN ; Kim Ping TAN ; Joey Chan Yiing BEH ; Eugenie Yi Kar CHAN ; Kenneth Fu Wen CHIN ; Zong Yi CHIN ; Wei Ming CHUA ; Aaron Wei-Loong CHONG ; Gary Tianyu GU ; Wenlu HOU ; Anna Chooi Yan LAI ; Rebekah Zhuyi LEE ; Perry Jia Ren LIEW ; May Yi Shan LIM ; Joshua Li Liang LIM ; Zehao TAN ; Eelin TAN ; Grace Siew Lim TAN ; Timothy Shao Ern TAN ; Eu Jin TAN ; Alexander Sheng Ming TAN ; Yet Yen YAN ; Winston Eng Hoe LIM
Singapore medical journal 2021;62(1):8-15
The Singapore Health Services cluster (SingHealth) radiology film archives are a valuable repository of local radiological cases dating back to the 1950s. Some of the cases in the archives are of historical medical interest, i.e. cerebral angiography in the workup of patients with hemiplegia. Other cases are of historical social interest, being conditions seen during earlier stages of Singapore's development, i.e. bound feet. The archives form a unique portal into the development of local radiology as well as the national development of Singapore. A selection from the archives is published in commemoration of the International Day of Radiology in 2020, as well as the 200th anniversary of the Singapore General Hospital in 2021. This pictorial essay comprises gastroenterology, musculoskeletal and obstetrics and gynaecology cases from the archives.
3.SingHealth Radiology Archives pictorial essay Part 1: cardiovascular, respiratory and neurological cases.
Mark Bangwei TAN ; Kim Ping TAN ; Joey Chan Yiing BEH ; Eugenie Yi Kar CHAN ; Kenneth Fu Wen CHIN ; Zong Yi CHIN ; Wei Ming CHUA ; Aaron Wei-Loong CHONG ; Gary Tianyu GU ; Wenlu HOU ; Anna Chooi Yan LAI ; Rebekah Zhuyi LEE ; Perry Jia Ren LIEW ; May Yi Shan LIM ; Joshua Li Liang LIM ; Zehao TAN ; Eelin TAN ; Grace Siew Lim TAN ; Timothy Shao Ern TAN ; Eu Jin TAN ; Alexander Sheng Ming TAN ; Yet Yen YAN ; Winston Eng Hoe LIM
Singapore medical journal 2020;61(12):633-640
The Singapore Health Services cluster (SingHealth) radiology film archives are a valuable repository of local radiological cases dating back to the 1950s. Some of the cases in the archives are of historical medical interest, i.e. cerebral angiography in the workup of patients with hemiplegia. Other cases are of historical social interest, being conditions seen during earlier stages of Singapore's development, i.e. bound feet. The archives form a unique portal into the development of local radiology as well as the national development of Singapore. A selection from the archives is published in 2020 in commemoration of the 20th anniversary of the formation of SingHealth, the 55th National Day of Singapore, and the 125th anniversary of the International Day of Radiology. This pictorial essay comprises cardiovascular, respiratory and neurological cases from the archives.
4.Cold chain time- and temperature-controlled transport of vaccines: a simulated experimental study
Chun Zheng NG ; Yen Loong LEAN ; Siang Fei YEOH ; Qi Ying LEAN ; Kah Seng LEE ; Amal Khalil SULEIMAN ; Kai Bin LIEW ; Yaman Walid KASSAB ; Yaser Mohammed AL-WORAFI ; Long Chiau MING
Clinical and Experimental Vaccine Research 2020;9(1):8-14
5.A bibliometric study of the publication type and citation count of Medical Journal of Malaysia for the period 1980-2016
Cheong Lieng Teng ; Kean Ghee Lim ; Ee Ming Khoo ; Chirk Jenn Ng ; Lee Yen Chong ; Mei Yee Lee ; Nawal Aqilah Amir ; Jia Ling Voon ; Wilson Wei Sheng Chin
International e-Journal of Science, Medicine and Education 2019;13(1):26-32
Objectives:
To evaluate study designs and citation counts of original research published in the Medical Journal of Malaysia (MJM).
Methods:
The bibliographic data of the MJM for the period 1980-2016 were retrieved from PubMed and analysed using Endnote bibliographic software. Study designs of original journal articles were analysed according to whether the articles were diagnostic study, prognostic study or clinical trial (collectively known as “evidence papers”). The citation counts of the original articles and case reports for the period 2012-2016 were compared in a sub-study using a case-control design.
Results:
A total of 3952 MJM journal items were retrieved from PubMed for the period 1980-2016; of these, 58.9% were original articles and 29.5% were case reports. Among the original articles, 14.6% were “evidence papers”; 2.3% were diagnostic studies, 7.7% were prognostic studies, 4.6% were clinical trials. In the study period 2012-2016, “other types of original articles” had statistically significantly more citations than case reports. However, there is no difference between “evidence papers” and case reports.
Conclusion
Our analysis shows the distribution of the types of articles appearing in the MJM for the period of study and serves as a reference for improving citations counts in the local context.
Bibliometrics
6.Guidelines for antimicrobial stewardship training and practice.
Christine B TENG ; Winnie LEE ; Chay Leng YEO ; Siok Ying LEE ; Tat Ming NG ; Siang Fei YEOH ; Wee Heng LIM ; Andrea L KWA ; Koh Cheng THOON ; Say Tat OOI ; Thean Yen TAN ; Li Yang HSU ; David C LYE ; Maciej Piotr CHLEBICKI
Annals of the Academy of Medicine, Singapore 2012;41(1):29-34
7.Major workplace related accidents in Singapore: A major trauma centre's experience.
Zhi Xu NG ; Li Tserng TEO ; Karen T S GO ; Yen Teng YEO ; Ming Terk CHIU
Annals of the Academy of Medicine, Singapore 2010;39(12):920-927
INTRODUCTIONMajor workplace related accidents pose a significant healthcare resource challenge in Singapore.
MATERIALS AND METHODSOur study looks at the epidemiology of patients who were admitted for workplace related accidents, in a single institution, with an Injury Severity Score of >9.
RESULTSThere were 196 cases of major workplace related accidents admitted between January 2006 and December 2007. The median age of patients admitted was 37 years with a large percentage being males (95.4%) and non-residents (57.1%). The most common ethnic group was Chinese (53.1%) followed by Indians (23.5%). The most common mechanism of injury was fall from height (66.3%) followed by injuries as a result of falling objects at work (21.9%). The percentage of patients who required surgical intervention was 69.9%. Patients admitted for major workplace related accidents had a median length of stay of 5 days in the hospital, a median length of 24 days of medical leave (ML), certifying them unfit for duty and the average cost of stay for each patient was S$11,000.
CONCLUSIONSWe have a better understanding of the epidemiology and socio-economic impact of workplace related accidents through this study. Workplace related accidents result in significant number of man-days lost from work and monetary cost to employers, medical insurance and the hospital. With an improved understanding, we propose methods to prevent and reduce such accidents in future. A direct consequence of which will be the possible reduction of hospitalisation costs and better allocation of healthcare resources in the future.
Accidents, Occupational ; trends ; Adult ; Female ; Humans ; Male ; Middle Aged ; Registries ; Singapore ; epidemiology ; Trauma Centers ; Trauma Severity Indices ; Wounds and Injuries ; epidemiology ; surgery ; Young Adult


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