Objective To compare the effects of ultrasound cycloplasty(UCP)and 810 nm laser photocoagulation for the treatment of refractory glaucoma.Methods In this prospective study,40 patients(40 eyes)with refractory glau-coma admitted to the hospital between June 2022 and March 2024 were selected and divided by the random number table method into a UCP group(20 cases)and an 810 laser group(20 cases).The UCP group received UCP treatment and the 810 laser group underwent transscleral 810 nm laser cyclophotocoagulation.The general data of the patients and their in-traocular pressures before surgery,1 day,2 weeks and 3 months after surgery were compared.Moreover,the ocular hemo-dynamics[including resistance index(RI)and peak systolic velocity(PSV)of the posterior short ciliary artery,central ret-inal artery and ocular artery],numerical rating scale(NRS)scores and visual acuity 3 months after surgery were compared with those before surgery.The occurrence of complications within 3 months after surgery was compared between the two groups.Results The intraocular pressure was decreased in both groups and the intraocular pressure in the UCP group was lower than that in the 810 laser group 1 day,2 weeks and 3 months after surgery(all P＜0.05).Compared with the 810 laser group,the UCP group had lower RI,PSV and NRS scores but higher visual acuity 3 months after surgery(all P＜0.05).There was no significant difference in incidence of complications between UCP and 810 laser groups at the end of the follow-up(10.00％vs.15.00％,P＞0.05).Conclusion Compared with transscleral 810 nm laser cyclophotocoagu-lation,UCP can more effectively lower the intraocular pressure,promote the recovery of visual acuity and relieve pain in patients with refractory glaucoma while having comparable safety.

Objective To compare the effects of ultrasound cycloplasty(UCP)and 810 nm laser photocoagulation for the treatment of refractory glaucoma.Methods In this prospective study,40 patients(40 eyes)with refractory glau-coma admitted to the hospital between June 2022 and March 2024 were selected and divided by the random number table method into a UCP group(20 cases)and an 810 laser group(20 cases).The UCP group received UCP treatment and the 810 laser group underwent transscleral 810 nm laser cyclophotocoagulation.The general data of the patients and their in-traocular pressures before surgery,1 day,2 weeks and 3 months after surgery were compared.Moreover,the ocular hemo-dynamics[including resistance index(RI)and peak systolic velocity(PSV)of the posterior short ciliary artery,central ret-inal artery and ocular artery],numerical rating scale(NRS)scores and visual acuity 3 months after surgery were compared with those before surgery.The occurrence of complications within 3 months after surgery was compared between the two groups.Results The intraocular pressure was decreased in both groups and the intraocular pressure in the UCP group was lower than that in the 810 laser group 1 day,2 weeks and 3 months after surgery(all P＜0.05).Compared with the 810 laser group,the UCP group had lower RI,PSV and NRS scores but higher visual acuity 3 months after surgery(all P＜0.05).There was no significant difference in incidence of complications between UCP and 810 laser groups at the end of the follow-up(10.00％vs.15.00％,P＞0.05).Conclusion Compared with transscleral 810 nm laser cyclophotocoagu-lation,UCP can more effectively lower the intraocular pressure,promote the recovery of visual acuity and relieve pain in patients with refractory glaucoma while having comparable safety.