1.Research progress of microfibril-associated protein 2 in malignant tumors
Zhijie DING ; Weiming YANG ; Yong YAN ; Miaokang XU ; Minglong HUANG ; Hao WANG ; Yongping ZHOU
Chinese Journal of Hepatobiliary Surgery 2025;31(7):557-560
Microfibrino-associated protein (MFAP) 2 is an extracellular matrix glycoprotein and a member of the MFAP family. It participates in the assembly of extracellular elastic microfibers.Upregulation of MFAP2 can promote the occurrence and development of various tumors and regulate multiple cancer-related signaling pathways and is related to their prognosis, making it a potential target for tumor treatment. This article summarizes the research progress on the pathogenesis, targeted therapy and prognosis of MFAP2 in malignant tumors.
2.Research progress of microfibril-associated protein 2 in malignant tumors
Zhijie DING ; Weiming YANG ; Yong YAN ; Miaokang XU ; Minglong HUANG ; Hao WANG ; Yongping ZHOU
Chinese Journal of Hepatobiliary Surgery 2025;31(7):557-560
Microfibrino-associated protein (MFAP) 2 is an extracellular matrix glycoprotein and a member of the MFAP family. It participates in the assembly of extracellular elastic microfibers.Upregulation of MFAP2 can promote the occurrence and development of various tumors and regulate multiple cancer-related signaling pathways and is related to their prognosis, making it a potential target for tumor treatment. This article summarizes the research progress on the pathogenesis, targeted therapy and prognosis of MFAP2 in malignant tumors.
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