Objective To investigate the efficacy of externally applied mirabilite combined with infrared irradiation in promoting wound healing following biliary tract surgery.Methods Patients who underwent open surgery for biliary tract disease in our department between January 2022 and April 2025 were randomly assigned to one of three groups:(1)Combination group(n=60),which received postoperative wound treatment with mirabilite application combined with infrared irradiation;(2)Mirabilite group(n=60),treated with mirabilite application alone;and(3)Infrared group(n=60),treated with infrared irradiation alone.The primary outcomes included wound healing grade on postoperative day 7,pain intensity measured on days 3,5,and 7,and wound healing status up to discharge.For cases with suboptimal healing,the duration required for complete healing following intervention was documented.Secondary outcomes encompassed length of postoperative hospital stay and Vancouver Scar Scale(VSS)scores—assessing scar pigmentation,thickness,vascularity,and pliability—evaluated at 3 months postoperatively.Results The combination group exhibited significantly lower rates of poor wound healing,shorter postoperative hospital stays,improved VSS scores—particularly in terms of scar thickness and pliability—and reduced pain levels on the 3rd and 5th postoperative days compared to the other two groups(P<0.05).Conclusions The combined use of mirabilite and infrared irradiation for surgical incisions following biliary tract surgery represents an effective,economical,and readily accessible adjuvant therapy.It significantly reduces the incidence of impaired wound healing and effectively alleviates early postoperative pain,thereby demonstrating strong potential for clinical promotion.

Objective To investigate the efficacy and safety of lobaplatin in promoting liver wound healing following hepatectomy for patients with primary hepatocellular carcinoma.Methods From January 2019 to June 2024,120 patients with primary hepatocellular carcinoma(HCC)at CNLC stages Ia to IIa were randomly divided into an observation group(n=60)and a control group(n=60).The observation group underwent hepatectomy and received lobaplatin application on the liver wound during surgery,while the control group underwent hepatectomy alone without lobaplatin application.All patients were followed up for 66 months.Postoperative levels of ALT,AST,blood creatinine,white blood cells,and platelets were compared between the two groups.Additionally,the incidence of hemorrhage and bile leakage was compared,as well as the recurrence-free survival time after surgery.Results There were no significant differences between the two groups in terms of postoperative ALT,AST,blood creatinine,white blood cell count,or platelet levels(P>0.05).Additionally,no significant differences were ob-served in the incidence of postoperative hemorrhage and bile leakage between the two groups(P>0.05).However,a significant difference was noted in recurrence-free survival time between the groups(P>0.05),with the recurrence-free survival curve indicating a higher recurrence-free survival rate in the observation group compared to the control group(P>0.05).Conclusions Lobaplatin application for liver wound healing in hepatectomy of patients with primary hepatocellular carcinoma represents a feasible,safe,and effective adjuvant therapy.This approach can decrease the early recurrence rate in patients with early-stage primary hepatocellular carcinoma,making it worthy of clinical promotion.

Objective To investigate the efficacy and safety of lobaplatin in promoting liver wound healing following hepatectomy for patients with primary hepatocellular carcinoma.Methods From January 2019 to June 2024,120 patients with primary hepatocellular carcinoma(HCC)at CNLC stages Ia to IIa were randomly divided into an observation group(n=60)and a control group(n=60).The observation group underwent hepatectomy and received lobaplatin application on the liver wound during surgery,while the control group underwent hepatectomy alone without lobaplatin application.All patients were followed up for 66 months.Postoperative levels of ALT,AST,blood creatinine,white blood cells,and platelets were compared between the two groups.Additionally,the incidence of hemorrhage and bile leakage was compared,as well as the recurrence-free survival time after surgery.Results There were no significant differences between the two groups in terms of postoperative ALT,AST,blood creatinine,white blood cell count,or platelet levels(P>0.05).Additionally,no significant differences were ob-served in the incidence of postoperative hemorrhage and bile leakage between the two groups(P>0.05).However,a significant difference was noted in recurrence-free survival time between the groups(P>0.05),with the recurrence-free survival curve indicating a higher recurrence-free survival rate in the observation group compared to the control group(P>0.05).Conclusions Lobaplatin application for liver wound healing in hepatectomy of patients with primary hepatocellular carcinoma represents a feasible,safe,and effective adjuvant therapy.This approach can decrease the early recurrence rate in patients with early-stage primary hepatocellular carcinoma,making it worthy of clinical promotion.

Objective To investigate the efficacy of externally applied mirabilite combined with infrared irradiation in promoting wound healing following biliary tract surgery.Methods Patients who underwent open surgery for biliary tract disease in our department between January 2022 and April 2025 were randomly assigned to one of three groups:(1)Combination group(n=60),which received postoperative wound treatment with mirabilite application combined with infrared irradiation;(2)Mirabilite group(n=60),treated with mirabilite application alone;and(3)Infrared group(n=60),treated with infrared irradiation alone.The primary outcomes included wound healing grade on postoperative day 7,pain intensity measured on days 3,5,and 7,and wound healing status up to discharge.For cases with suboptimal healing,the duration required for complete healing following intervention was documented.Secondary outcomes encompassed length of postoperative hospital stay and Vancouver Scar Scale(VSS)scores—assessing scar pigmentation,thickness,vascularity,and pliability—evaluated at 3 months postoperatively.Results The combination group exhibited significantly lower rates of poor wound healing,shorter postoperative hospital stays,improved VSS scores—particularly in terms of scar thickness and pliability—and reduced pain levels on the 3rd and 5th postoperative days compared to the other two groups(P<0.05).Conclusions The combined use of mirabilite and infrared irradiation for surgical incisions following biliary tract surgery represents an effective,economical,and readily accessible adjuvant therapy.It significantly reduces the incidence of impaired wound healing and effectively alleviates early postoperative pain,thereby demonstrating strong potential for clinical promotion.