Objective: To evaluate the performance of supplemental automated breast ultrasound (ABUS) added to mammography-based breast cancer screening for women with nondense breasts. Materials and Methods: A retrospective search of radiology databases at two tertiary institutions identified asymptomatic women with nondense breasts who underwent breast cancer screening using both digital mammography (DM) and supplemental ABUS between January 2020 and December 2023. We excluded women without sufficient follow-up data or those without an established final diagnosis, including histopathologic results. The performance measures of DM alone and ABUS combined with DM (ABUS plus DM) were compared. The primary outcome was the cancer detection rate (CDR), and the secondary outcomes were sensitivity and specificity. Subgroup analyses were performed for women with scattered fibroglandular density and almost entirely fatty breasts. Results: A total of 2,904 pairs of screening examinations were performed in 1,683 women (59 ± 10 years), detecting 26 cancers. In comparison with DM alone, ABUS plus DM showed higher CDR (9.0 vs. 7.9 per 1,000 examinations, P < 0.001), higher sensitivity (100% [26/26] vs. 88.5% [23/26], P < 0.001), and lower specificity (95.0% [2,735/2,878] vs. 97.9% [2,817/2,878], P < 0.001). In women with scattered fibroglandular density, ABUS increased the CDR from 7.4 to 8.5 per 1,000 examinations and improved the sensitivity from 87.0% [20/23] to 100% [23/23] (P < 0.001). In women with almost entirely fatty breasts, ABUS plus DM showed the same CDR (16.4 per 1,000 examinations) and sensitivity (100% [3/3]) as DM alone. Three cancers (11.5% [3/26]), all of which were stage T1N0, were detected only by supplemental ABUS. Conclusion Supplemental ABUS improved cancer detection and sensitivity in women with nondense breasts, with the benefits primarily observed in those with scattered fibroglandular density.

Background: This study aimed to investigate the association between obesity and periodontitis among Korean adults and examinewhether the intensity of physical activity modifies this relationship. Methods: The analysis included 11,230 adults aged 19 years and older who participated in the 7th Korea National Health andNutrition Examination Survey between 2016 and 2018. Periodontal status was assessed using the community periodontal index, and obesity was defined as a body mass index of 23.0 kg/m2 or greater. Physical activity intensity was categorized as none, moderate, or high. Multivariable logistic regression analyses, including interaction terms, were conducted to assess the moderating effect of exercise intensity on the association between obesity and periodontitis. Results: Obesity was significantly associated with high-risk periodontitis, and this association varied according to exerciseintensity. The adjusted odds ratios for obesity were 1.23 (95% confidence interval [CI]: 1.09∼1.40) among non-exercisers, 1.43 (95% CI: 1.09∼1.87) among those engaging in moderate-intensity exercise only, and 2.21 (95% CI: 1.27∼3.85) among those engaging in high-intensity exercise only. Conclusion Obesity is a significant risk factor for periodontitis in Korean adults, and the intensity of physical activity modifies thisrelationship. Contrary to expectations, high-intensity exercise may increase the risk of periodontal disease in individuals with obesity. These findings underscore the importance of personalized exercise recommendations and the need to consider metabolic and behavioral factors in oral health promotion strategies.

Background: We evaluated severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)-specific humoral and cellular responses for up to 6 months after the 3rd dose of ancestral coronavirus disease 2019 (COVID-19) vaccination in people living with HIV (PLWH) and healthy controls (HCs) who were not infected with COVID-19. Methods: Anti-spike receptor-binding domain IgG (anti-RBD IgG) concentrations using chemiluminescence immunoassay and neutralizing antibodies using focus reduction neutralization test (FRNT) were assessed at 1 week after each dose of vaccination, and 3 and 6 months after the 3rd dose in 62 PLWH and 25 HCs. T-cell responses using intracellular cytokine stain were evaluated at 1 week before, and 1 week and 6 months after the 3rd dose. Results: At 1 week after the 3rd dose, adequate anti-RBD IgG (> 300 binding antibody unit /mL) was elicited in all PLWH except for one patient with 36 CD4 T-cell count/mm3 . The geometric mean titers of 50% FRNT against wild type (WT) and omicron BA.5 strains of SARS-CoV-2 in PLWH with CD4 T-cell count ≥ 500 cells/mm3(high CD4 recovery, HCDR) were comparable to HC, but they were significantly decreased in PLWH with CD4 T-cell count < 500/mm3 (low CD4 recovery, LCDR). After adjusting for age, gender, viral suppression, and number of preexisting comorbidities, CD4 T-cell counts < 500/mm3 significantly predicted a poor magnitude of neutralizing antibodies against WT, omicron BA.5, and XBB 1.5 strains among PLWH. Multivariable linear regression adjusting for age and gender revealed that LCDR was associated with reduced neutralizing activity (P = 0.017) and interferon-γ-producing T-cell responses (P = 0.049 for CD T-cell; P = 0.014 for CD8 T-cell) against WT, and strongly associated with more decreased cross-neutralization against omicron BA.5 strains (P < 0.001). Conclusion HCDR demonstrated robust humoral and cell-mediated immune responses after a booster dose of ancestral SARS-CoV-2 vaccine, whereas LCDR showed diminished immune responses against WT virus and more impaired cross-neutralization against omicron BA.5 strain.

Background: We evaluated severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)-specific humoral and cellular responses for up to 6 months after the 3rd dose of ancestral coronavirus disease 2019 (COVID-19) vaccination in people living with HIV (PLWH) and healthy controls (HCs) who were not infected with COVID-19. Methods: Anti-spike receptor-binding domain IgG (anti-RBD IgG) concentrations using chemiluminescence immunoassay and neutralizing antibodies using focus reduction neutralization test (FRNT) were assessed at 1 week after each dose of vaccination, and 3 and 6 months after the 3rd dose in 62 PLWH and 25 HCs. T-cell responses using intracellular cytokine stain were evaluated at 1 week before, and 1 week and 6 months after the 3rd dose. Results: At 1 week after the 3rd dose, adequate anti-RBD IgG (> 300 binding antibody unit /mL) was elicited in all PLWH except for one patient with 36 CD4 T-cell count/mm3 . The geometric mean titers of 50% FRNT against wild type (WT) and omicron BA.5 strains of SARS-CoV-2 in PLWH with CD4 T-cell count ≥ 500 cells/mm3(high CD4 recovery, HCDR) were comparable to HC, but they were significantly decreased in PLWH with CD4 T-cell count < 500/mm3 (low CD4 recovery, LCDR). After adjusting for age, gender, viral suppression, and number of preexisting comorbidities, CD4 T-cell counts < 500/mm3 significantly predicted a poor magnitude of neutralizing antibodies against WT, omicron BA.5, and XBB 1.5 strains among PLWH. Multivariable linear regression adjusting for age and gender revealed that LCDR was associated with reduced neutralizing activity (P = 0.017) and interferon-γ-producing T-cell responses (P = 0.049 for CD T-cell; P = 0.014 for CD8 T-cell) against WT, and strongly associated with more decreased cross-neutralization against omicron BA.5 strains (P < 0.001). Conclusion HCDR demonstrated robust humoral and cell-mediated immune responses after a booster dose of ancestral SARS-CoV-2 vaccine, whereas LCDR showed diminished immune responses against WT virus and more impaired cross-neutralization against omicron BA.5 strain.

Background: This study was conducted to investigate the awareness of maternity protection policy among dentists and dental hygienists, identify maternity protection policies with low awareness, and determine whether there are differences in awareness depending on the occupation of dental professionals and the presence of children. Methods: We conducted face-to-face and online surveys with dentists and dental hygienists working in dental medical institutions, and analyzed the data of a total of 165 people. In order to determine awareness of maternity protection policy, 19 maternity protection systems were structured to respond with ‘know’ or ‘don’t know’, and one question was designed to survey overall awareness of maternity protection systems. Results: The study subjects were 23.0% dentists and 77.0% dental hygienists. The overall subjective awareness of the maternity protection policy was 1.53 out of 4 points on average, and by job title, the group of dentists as business owners had the highest subjective awareness at 2.0 points, which was statistically significantly higher than the group of dentists as office workers and dental hygienists as team members (p＜0.05). Those with children had higher awareness of all maternity protection policies than those without children. Conclusion In order to prevent career breaks in dental personnel and to balance work and family life, both employers and employees of dental medical institutions need to correctly understand the maternity protection policy. To this end, the government and dental personnel-related organizations should specifically publicize the changing maternity protection policy, and dental medical institutions should create a working environment where employees can utilize the maternity protection policy according to their life cycle.

Background: This study was conducted to investigate the awareness of maternity protection policy among dentists and dental hygienists, identify maternity protection policies with low awareness, and determine whether there are differences in awareness depending on the occupation of dental professionals and the presence of children. Methods: We conducted face-to-face and online surveys with dentists and dental hygienists working in dental medical institutions, and analyzed the data of a total of 165 people. In order to determine awareness of maternity protection policy, 19 maternity protection systems were structured to respond with ‘know’ or ‘don’t know’, and one question was designed to survey overall awareness of maternity protection systems. Results: The study subjects were 23.0% dentists and 77.0% dental hygienists. The overall subjective awareness of the maternity protection policy was 1.53 out of 4 points on average, and by job title, the group of dentists as business owners had the highest subjective awareness at 2.0 points, which was statistically significantly higher than the group of dentists as office workers and dental hygienists as team members (p＜0.05). Those with children had higher awareness of all maternity protection policies than those without children. Conclusion In order to prevent career breaks in dental personnel and to balance work and family life, both employers and employees of dental medical institutions need to correctly understand the maternity protection policy. To this end, the government and dental personnel-related organizations should specifically publicize the changing maternity protection policy, and dental medical institutions should create a working environment where employees can utilize the maternity protection policy according to their life cycle.

Background: We evaluated severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)-specific humoral and cellular responses for up to 6 months after the 3rd dose of ancestral coronavirus disease 2019 (COVID-19) vaccination in people living with HIV (PLWH) and healthy controls (HCs) who were not infected with COVID-19. Methods: Anti-spike receptor-binding domain IgG (anti-RBD IgG) concentrations using chemiluminescence immunoassay and neutralizing antibodies using focus reduction neutralization test (FRNT) were assessed at 1 week after each dose of vaccination, and 3 and 6 months after the 3rd dose in 62 PLWH and 25 HCs. T-cell responses using intracellular cytokine stain were evaluated at 1 week before, and 1 week and 6 months after the 3rd dose. Results: At 1 week after the 3rd dose, adequate anti-RBD IgG (> 300 binding antibody unit /mL) was elicited in all PLWH except for one patient with 36 CD4 T-cell count/mm3 . The geometric mean titers of 50% FRNT against wild type (WT) and omicron BA.5 strains of SARS-CoV-2 in PLWH with CD4 T-cell count ≥ 500 cells/mm3(high CD4 recovery, HCDR) were comparable to HC, but they were significantly decreased in PLWH with CD4 T-cell count < 500/mm3 (low CD4 recovery, LCDR). After adjusting for age, gender, viral suppression, and number of preexisting comorbidities, CD4 T-cell counts < 500/mm3 significantly predicted a poor magnitude of neutralizing antibodies against WT, omicron BA.5, and XBB 1.5 strains among PLWH. Multivariable linear regression adjusting for age and gender revealed that LCDR was associated with reduced neutralizing activity (P = 0.017) and interferon-γ-producing T-cell responses (P = 0.049 for CD T-cell; P = 0.014 for CD8 T-cell) against WT, and strongly associated with more decreased cross-neutralization against omicron BA.5 strains (P < 0.001). Conclusion HCDR demonstrated robust humoral and cell-mediated immune responses after a booster dose of ancestral SARS-CoV-2 vaccine, whereas LCDR showed diminished immune responses against WT virus and more impaired cross-neutralization against omicron BA.5 strain.

Background: This study was conducted to investigate the awareness of maternity protection policy among dentists and dental hygienists, identify maternity protection policies with low awareness, and determine whether there are differences in awareness depending on the occupation of dental professionals and the presence of children. Methods: We conducted face-to-face and online surveys with dentists and dental hygienists working in dental medical institutions, and analyzed the data of a total of 165 people. In order to determine awareness of maternity protection policy, 19 maternity protection systems were structured to respond with ‘know’ or ‘don’t know’, and one question was designed to survey overall awareness of maternity protection systems. Results: The study subjects were 23.0% dentists and 77.0% dental hygienists. The overall subjective awareness of the maternity protection policy was 1.53 out of 4 points on average, and by job title, the group of dentists as business owners had the highest subjective awareness at 2.0 points, which was statistically significantly higher than the group of dentists as office workers and dental hygienists as team members (p＜0.05). Those with children had higher awareness of all maternity protection policies than those without children. Conclusion In order to prevent career breaks in dental personnel and to balance work and family life, both employers and employees of dental medical institutions need to correctly understand the maternity protection policy. To this end, the government and dental personnel-related organizations should specifically publicize the changing maternity protection policy, and dental medical institutions should create a working environment where employees can utilize the maternity protection policy according to their life cycle.

Background: We evaluated severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2)-specific humoral and cellular responses for up to 6 months after the 3rd dose of ancestral coronavirus disease 2019 (COVID-19) vaccination in people living with HIV (PLWH) and healthy controls (HCs) who were not infected with COVID-19. Methods: Anti-spike receptor-binding domain IgG (anti-RBD IgG) concentrations using chemiluminescence immunoassay and neutralizing antibodies using focus reduction neutralization test (FRNT) were assessed at 1 week after each dose of vaccination, and 3 and 6 months after the 3rd dose in 62 PLWH and 25 HCs. T-cell responses using intracellular cytokine stain were evaluated at 1 week before, and 1 week and 6 months after the 3rd dose. Results: At 1 week after the 3rd dose, adequate anti-RBD IgG (> 300 binding antibody unit /mL) was elicited in all PLWH except for one patient with 36 CD4 T-cell count/mm3 . The geometric mean titers of 50% FRNT against wild type (WT) and omicron BA.5 strains of SARS-CoV-2 in PLWH with CD4 T-cell count ≥ 500 cells/mm3(high CD4 recovery, HCDR) were comparable to HC, but they were significantly decreased in PLWH with CD4 T-cell count < 500/mm3 (low CD4 recovery, LCDR). After adjusting for age, gender, viral suppression, and number of preexisting comorbidities, CD4 T-cell counts < 500/mm3 significantly predicted a poor magnitude of neutralizing antibodies against WT, omicron BA.5, and XBB 1.5 strains among PLWH. Multivariable linear regression adjusting for age and gender revealed that LCDR was associated with reduced neutralizing activity (P = 0.017) and interferon-γ-producing T-cell responses (P = 0.049 for CD T-cell; P = 0.014 for CD8 T-cell) against WT, and strongly associated with more decreased cross-neutralization against omicron BA.5 strains (P < 0.001). Conclusion HCDR demonstrated robust humoral and cell-mediated immune responses after a booster dose of ancestral SARS-CoV-2 vaccine, whereas LCDR showed diminished immune responses against WT virus and more impaired cross-neutralization against omicron BA.5 strain.

Background: This scoping review examined research on artificial intelligence (AI) published in Korean academic journals in thefields of dental hygiene and dentistry. The Context–Concept–Maturity framework was applied to compare research trends and identify future directions. Methods: Following the Arksey and O’Malley framework, with extensions by Levac et al., the review adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines. Domestic academic journals published between January 1, 2020, and September 30, 2025, were searched in KISS, RISS, ScienceON, and DBpia. Studies were screened, extracted, and coded according to population, concept, and context criteria, yielding 70 eligible articles (26 in dental hygiene and 44 in dentistry). Results: In dental hygiene, most research focused on education (38.5%) and community/public oral health (38.5%), while clinicalapplications were limited (7.7%). Major conceptual domains included education/training tools (42.3%), workflow/automation (38.5%), prediction (15.4%), and classification (3.8%). Dentistry studies were predominantly clinically oriented and imagingbased, emphasizing classification, automation, and segmentation. Maturity analysis indicated that dentistry primarily occupied Stage 2 (application; ∼84.1%), whereas dental hygiene showed a dual distribution across Stage 1 (exploration; 46.2%) and Stage 2 (application; 46.2%), with limited Stage 3 (integration; 7.7%) studies. Conclusion AI research in Korea exhibits divergent developmental trajectories. Dental hygiene research emphasizes education,prevention, and public oral health, combining exploratory and applied approaches, while dentistry demonstrates greater clinical integration and application-level maturity. Advancing AI maturity in dental hygiene will require expansion of clinical data–driven studies, incorporation of AI and data literacy into curricula, standardized integration of unstructured and clinical data, multicenter long-term validation, and the development of ethical and performance governance frameworks.