Objective To investigate the effect of ankle pump exercises,based on hemodynamic mechanisms,on the prevention of venous thrombosis in stroke patients.Methods A total of 110 stroke patients,admitted to a tertiary A hospital in Jiangsu Province between June 2023 and June 2024,were selected using a convenience sampling method.The patients were divided into an experimental group and a control group,with 55 patients in each group.The experimental group received ankle pump exercise nursing interventions based on hemodynamic mechanisms,while the control group received routine nursing interventions.The incidence of lower extremity deep vein thrombosis,Pittsburgh Rehabilitation Participation Scale scores,subjective perceived fatigue,and exercise self-efficacy scores were compared between 2 groups on the 7th day of hospitalization.Results No dropouts occurred in either group.The incidence of deep vein thrombosis was significantly lower in the experimental group than it in the control group(P=0.004).The Pittsburgh Rehabilitation Participation scores on day 1,3,5,and 7 were higher in the experimental group compared to them in the control group(P＜0.001).A significant time-dependent trend was observed in Pittsburgh Rehabilitation Participation scores(P=0.034).Subjective fatigue was significantly lower in the experimental group at various time points(P＜0.001).Both groups showed an increase in exercise self-efficacy over time(P=0.016),with the experimental group demonstrating higher exercise self-efficacy than the control group on the day before discharge(P=0.003).Conclusion Ankle pump exercises,based on hemodynamic mechanisms,can effectively reduce the incidence of deep vein thrombosis in stroke patients,enhance rehabilitation participation and exercise self-efficacy,without increasing subjective fatigue.

Objective To investigate the effect of ankle pump exercises,based on hemodynamic mechanisms,on the prevention of venous thrombosis in stroke patients.Methods A total of 110 stroke patients,admitted to a tertiary A hospital in Jiangsu Province between June 2023 and June 2024,were selected using a convenience sampling method.The patients were divided into an experimental group and a control group,with 55 patients in each group.The experimental group received ankle pump exercise nursing interventions based on hemodynamic mechanisms,while the control group received routine nursing interventions.The incidence of lower extremity deep vein thrombosis,Pittsburgh Rehabilitation Participation Scale scores,subjective perceived fatigue,and exercise self-efficacy scores were compared between 2 groups on the 7th day of hospitalization.Results No dropouts occurred in either group.The incidence of deep vein thrombosis was significantly lower in the experimental group than it in the control group(P=0.004).The Pittsburgh Rehabilitation Participation scores on day 1,3,5,and 7 were higher in the experimental group compared to them in the control group(P＜0.001).A significant time-dependent trend was observed in Pittsburgh Rehabilitation Participation scores(P=0.034).Subjective fatigue was significantly lower in the experimental group at various time points(P＜0.001).Both groups showed an increase in exercise self-efficacy over time(P=0.016),with the experimental group demonstrating higher exercise self-efficacy than the control group on the day before discharge(P=0.003).Conclusion Ankle pump exercises,based on hemodynamic mechanisms,can effectively reduce the incidence of deep vein thrombosis in stroke patients,enhance rehabilitation participation and exercise self-efficacy,without increasing subjective fatigue.

MRI technology has been widely used in brain connectivity analysis to explore the neurobiological mechanism of ASD. Analysis of brain structural connectivity found atypical growth and development in patients with ASD, excessive growth in infancy, and excessive decline in functions from adolescence to middle age. Functional connectivity analysis suggests that default mode network (DMN) may be related to theory of mind (ToM) and self-referential processing, abnormal salience network (SN) connections can lead to social communication disorders, and abnormal reward network (RN) may be related to repetitive and restricted behaviors. Effective connectivity analysis found that information transmission between brain regions was abnormal in ASD patients, which was associated with social dysfunction. This article introduces the latest development of MRI research, and discusses the differences between ASD patients and normal human brain connections, so as to provide theoretical reference for further investigations of the neural activity mechanism of ASD patients.

MRI technology has been widely used in brain connectivity analysis to explore the neurobiological mechanism of ASD. Analysis of brain structural connectivity found atypical growth and development in patients with ASD, excessive growth in infancy, and excessive decline in functions from adolescence to middle age. Functional connectivity analysis suggests that default mode network (DMN) may be related to theory of mind (ToM) and self-referential processing, abnormal salience network (SN) connections can lead to social communication disorders, and abnormal reward network (RN) may be related to repetitive and restricted behaviors. Effective connectivity analysis found that information transmission between brain regions was abnormal in ASD patients, which was associated with social dysfunction. This article introduces the latest development of MRI research, and discusses the differences between ASD patients and normal human brain connections, so as to provide theoretical reference for further investigations of the neural activity mechanism of ASD patients.