Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by motor dysfunction, with its pathophysiology mainly involving the basal ganglia-thalamocortical pathway. In recent years, the role of cerebellar neural networks in PD has garnered increasing attention. The cerebellum not only plays a role in motor control but also influences non-motor functions such as cognition and emotion. Through its extensive connections with the basal ganglia and cerebral cortex, the cerebellum is critically involved in regulating neural networks in PD. This review summarizes the structural and functional changes of the cerebellum in PD patients, as well as the pathophysiological interactions between cerebellar networks and the basal ganglia-thalamocortical pathway, which collectively impact both motor and non-motor functions in PD. The aim of the review is to provide a new perspective on the role of the cerebellum in the pathogenesis of PD.

Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by motor dysfunction, with its pathophysiology mainly involving the basal ganglia-thalamocortical pathway. In recent years, the role of cerebellar neural networks in PD has garnered increasing attention. The cerebellum not only plays a role in motor control but also influences non-motor functions such as cognition and emotion. Through its extensive connections with the basal ganglia and cerebral cortex, the cerebellum is critically involved in regulating neural networks in PD. This review summarizes the structural and functional changes of the cerebellum in PD patients, as well as the pathophysiological interactions between cerebellar networks and the basal ganglia-thalamocortical pathway, which collectively impact both motor and non-motor functions in PD. The aim of the review is to provide a new perspective on the role of the cerebellum in the pathogenesis of PD.