Objective:To identify the risk factors for myocardial injury after non-cardiac surgery.Methods:The medical records of adult patients admitted to the intensive care unit of Peking University First Hospital after non-cardiac surgery from June 2017 to June 2018 were retrospectively collected.Myocardial injury was defined as serum cardiac troponin I concentration>0.06 μg/L within 3 days after operation, and the patients were divided into myocardial injury group and non-myocardial injury group.The perioperative data of patients were obtained through searching the electronic medical record system.The variables of which P values were less than 0.05 would enter the logistic regression analysis to stratify the risk factors for myocardial injury after non-cardiac surgery. Results:A total of 752 patients were included in the study, and the incidence of myocardial injury occurred after non-cardiac surgery was 15.7%.Emergency operation and highest lactic acid concentration during operation were the independent risk factors for myocardial injury after non-cardiac surgery.Conclusion:Emergency operation and highest lactic acid concentration during operation are the independent risk factors for myocardial injury after non-cardiac surgery.

Background Congenital stationary night blindness (CSNB) is a common genetic eye disease.Retinal angiogenesis is rarely obtained in retinal degeneration animal.The effects of CSNB on retinal angiogenesis require further study.Objective This study was to improve Chinese ink perfusion technology and to explore the effect of CSNB on oxygen induced neovascularization.Methods Eighteen clean 7-day old SD rats and 18 clean 7-day old CSNB rats were included,twelve SD rats and twelve CSNB rats were chosen randomly for oxygen induced retinopathy (OIR) modeling,and served as OIR group,six SD rats and six CSNB rats were chosen as normal control.Nine rats were chosen randomly from both SD rats and CSNB rats in OIR group,respectively.The rats were separated into 1 ∶ 1 ratio ink group,2 ∶ 1 ratio ink group and conventional ink group,which were perfused with 1 ∶ 1 ratio ink perfusate,2 ∶ 1 ratio ink perfusate and conventional ink,respectively.The unilateral eyes of the rats were prepared for whole-mount retina,the other eyes were performed for paraffin imbedding.The quality of retinal vascular imaging were compared among different ink perfusate groups.The normal control rats,three SD rats in OIR group and three CSNB rats in OIR group were perfused with 2 ∶ 1 ratio ink perfusate.Histopathology examination was performed on the paraffin section,and the number of nuclei breakthrough the inner limiting membrane were counted.Immunocytochemistry were performed on the paraffin section for detecting the expression of von Wilebrand factor (vWF).Results Compared with 1 ∶ 1 ratio ink perfusion and conventional ink perfusion,2 ∶ 1 ratio ink perfusion showed the full vascular net clearly.Histopathology showed that the structure of retina was normal in the normal control group,and there were no endothelial nuclei breakthrough the inner limiting membrane.A large number of endothelial nuclei breakthrough the inner limiting membrane in the OIR group,the number of endothelial nuclei breaking through the inner limiting membrane were (23.08±2.99)/slide and (41.12±9.36)/slide for SD rats and CSNB rats,respectively.The number of endothelial nuclei breakthrough inner limiting membrane was higher in the CSNB rats than that in the SD rats,with no difference between the two group (q =1.70,P =0.50).Immunocytochemistry results showed that v-WF was positive expressed in the cells breakthrough inner limiting membrane.Conclusions Improved ink perfusion method was an easy-to-use whole-mount retina method with good repeatability.Hyperoxia can induce retinal neovascularization of CSNB rats.

Objective To investigate the invasion characteristics of retinal diseases,consultation experiences as well as medical assessment for pilots,and put forward the corresponding countermeasures.Methods Medical records of 4 retinal disease cases,which were diagnosed by Department of Aviation in the 153th Hospital of PLA from June 2009 to July 2014.Results ①Four male pilots (5 eyes) were diagnosed as three sorts of retinal diseases:2 cases of central serous chorioretinopathy,1 case of branch retinal vein occlusion,1 case (2 eyes) of diabetic retinopathy.② Except 1 pilot (2 eyes) with diabetic retinopathy,the rest pilots complained discomfort of eyes,such as decreased vision,blurred vision and visual distortion.They were hospitalized and drug treated as the retinal diseases were diagnosed by the examinations of fundus,visual field and optical coherence tomography and fundus fluorescein angiography.③In above 4 cases (5 eyes),2 were central serous chorioretinopathy and pilots were qualified after the treatment and 3 months medical observation.The other 2 cases (3 eyes) were branch retinal vein occlusion and diabetic retinopathy.They were qualified as they recovered.Conclusions The medical assessment of retinal disease should be done in accordance with the results of treatment and visual function test.After the cure of central serous chorioretinopathy,1-3 months medical observation is suggested and the qualification would be issued if no recurrence and disturbed visual function were observed.The cured pilot who is free from branch retinal vein occlusion and diabetic retinopathy and with normal visual function would be qualified for flying.

Objective To investigate the invasion characteristics of retinal diseases,consultation experiences as well as medical assessment for pilots,and put forward the corresponding countermeasures.Methods Medical records of 4 retinal disease cases,which were diagnosed by Department of Aviation in the 153th Hospital of PLA from June 2009 to July 2014.Results ①Four male pilots (5 eyes) were diagnosed as three sorts of retinal diseases:2 cases of central serous chorioretinopathy,1 case of branch retinal vein occlusion,1 case (2 eyes) of diabetic retinopathy.② Except 1 pilot (2 eyes) with diabetic retinopathy,the rest pilots complained discomfort of eyes,such as decreased vision,blurred vision and visual distortion.They were hospitalized and drug treated as the retinal diseases were diagnosed by the examinations of fundus,visual field and optical coherence tomography and fundus fluorescein angiography.③In above 4 cases (5 eyes),2 were central serous chorioretinopathy and pilots were qualified after the treatment and 3 months medical observation.The other 2 cases (3 eyes) were branch retinal vein occlusion and diabetic retinopathy.They were qualified as they recovered.Conclusions The medical assessment of retinal disease should be done in accordance with the results of treatment and visual function test.After the cure of central serous chorioretinopathy,1-3 months medical observation is suggested and the qualification would be issued if no recurrence and disturbed visual function were observed.The cured pilot who is free from branch retinal vein occlusion and diabetic retinopathy and with normal visual function would be qualified for flying.