1.Construction of a health emergency response capability evaluation system for nuclear radiation emergencies
Meiru GUO ; Ximing FU ; Jianbiao CAO ; Huifang CHEN ; Long YUAN
Chinese Journal of Radiological Health 2026;35(1):43-48
Objective To address the safety challenges arising from the rapid development of nuclear energy and technology, assess the current status of health emergency response capabilities in nuclear radiation emergencies, and promote capacity enhancement. Methods A preliminary evaluation system for health emergency response capability in nuclear radiation emergencies was developed based on a literature review. Two rounds of Delphi expert consultation (n = 20) were conducted, and the analytic hierarchy process was employed to establish judgment matrices for assigning indicator weights. Results The finalized system included six primary indicators (radiation protection capability, triage capability, decontamination and evacuation capability, medical treatment capability, radiation detection capability, and radiation dose estimation capability), along with 29 secondary indicators, such as capability for setting up emergency zones, capability for protecting personnel from internal and external contamination, on-site first aid capability, and personal dose monitoring capability. The expert response rate was 0.95, and the expert authority coefficient reached 0.80. The Kendall’s coefficient of concordance was W = 0.288 (P<0.01) for the first round of expert consultation and W = 0.308 (P<0.01) for the second round. Both rounds demonstrated high agreement among experts, and the consultation questionnaires passed reliability and validity tests. Conclusion By integrating qualitative analysis and quantitative calculation, this study developed a scientifically sound and operationally feasible evaluation system. This system will help identify gaps in health emergency response capabilities and provide scientific guidance and a decision-making basis for optimizing emergency plans and improving the level of health emergency response in nuclear radiation emergencies.
2.Application value of assisted compressed sensing combined with deep reconstruction in MR abdominal T2WI
Yonghui XIAO ; Dongming LIAO ; Ruxin TANG ; Meiru WEN ; Ailin CHEN
Journal of Practical Radiology 2025;41(4):678-682
Objective To analyze the application value of assisted compressed sensing(ACS)combined with deep reconstruction(DR)(ACS+DR)algorithm in MR abdominal T2WI.Methods A total of 60 patients were prospectively selected to undergo three types of respiratory-triggered transverse T2 sequence scans:fast spin echo(FSE),propeller scanning(ARMS),and ACS+DR.Two radiologists independently evaluated the images for respiratory motion artifacts,gastrointestinal peristalsis artifacts,sharpness of intrahepatic vessel and bile duct,lesion clarity,and overall image quality.Additionally,the signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),and contrast ratio(CR)between lesions and liver parenchyma signal intensity were calculated.Wilcoxon and independent sample Mann-Whitney U tests were used to compare objective scores and subjective evaluations among different groups.Results The scan time for the ACS+DR sequence was 35 s,for the ARMS sequence 180 s,and for the FSE sequence 210 s.The ACS+DR sequence showed superior performance over the other sequences in terms of scan time,respiratory motion artifacts,intrahepatic vessel and bile duct sharpness,lesion clarity,and overall image quality(P<0.05).Compared with FSE sequence,the ARMS and ACS+DR sequences exhibited higher SNR,CNR,and CR(P<0.05).The ACS+DR sequence showed better SNR and CNR than the ARMS sequence(P<0.05);however,there was no significant difference between the two sequences in CR(P>0.05).No significant difference was found among the three sequences in the number of detected lesions(P>0.05).Conclusion The ACS+DR reconstruction algorithm for upper abdominal imaging not only ensures high image quality but also significantly improves scan speed,making it valuable for clinical application.
3.Progress in trauma-informed care education research abroad
Lingxiao HE ; Meiru CHEN ; Juan LÜ ; Ying DU ; Dengbin LIAO
Chinese Journal of Medical Education Research 2025;24(2):250-255
Trauma-informed care is a model of care in which healthcare professionals implement targeted interventions based on fully understanding of patients' trauma experiences, aiming to reduce psychological trauma symptoms, prevent re-traumatization, and improve health outcomes. Since the introduction of this concept, it has been applied in various fields, including medical education, mental health, obstetrics, and emergency care. The implementation of trauma-informed care requires targeted education and training for healthcare professionals; however, there is currently insufficient understanding of trauma-informed care among these professionals. Additionally, there are significant variations in the scope, content, model, and effectiveness of trauma-informed care education. This study aims to review the existing state of trauma-informed care education internationally, identify current research hotspots and shortcomings, and provide references for the future design and implementation of trauma-informed care education in China.
4.Research hotspots and trends of emergency response to public health emergencies in China
Meiru GUO ; Cuiping LEI ; Ximing FU ; Huifang CHEN ; Jianbiao CAO ; Long YUAN
Chinese Journal of Radiological Health 2025;34(1):61-66
Objective Emergency response to public health emergencies constitutes a vital component of the modernization of national governance systems and capacities, directly impacting national security, social stability, and public health. This study aims to analyze the key issues and research hotspots in the field of emergency response to public health emergencies, providing theoretical foundations and practical guidance for formulating scientific and effective emergency strategies and policies. Ultimately, it seeks to enhance the nation’s capability to respond to public health emergencies and safeguard public health. Methods Using core journals indexed in the China National Knowledge Infrastructure (CNKI) database as the data source,
5.Effects of behavior change intervention based on multiple-theory model in patients with dyslipidemic ischemic stroke
Jing WANG ; Yitong CHEN ; Meiru WU ; Meixia YANG ; Shanshan PEI ; Yongmei DENG
Journal of Clinical Medicine in Practice 2025;29(16):46-50
Objective To explore the effects of behavior change intervention based on the multi-ple-theory model on patients with dyslipidemic ischemic stroke.Methods A total of 93 patients with dyslipidemic ischemic stroke who were hospitalized in the vascular neurology ward of Beijing Tiantan Hospital,Capital Medical University from January to August 2024 were selected as the study subjects using the convenience sampling method.They were randomly divided into control group(n=49)and intervention group(n=44)using the envelope-drawing method.Patients in the control group re-ceived routine stroke health education,while those in the intervention group underwent a 3-month be-havior change program guided by the multiple-theory model.The levels of healthy behaviors,body mass index(BMI),total cholesterol(TC),triglycerides(TG),high-density lipoprotein(HDL-C),and low-density lipoprotein(LDL-C)were compared between the two groups.Results There were no statistically significant differences in general information and disease-related data between the two groups(P>0.05).At 1-,3-,and 6-month after the intervention,the level of healthy behaviors in the intervention group was higher than that in the control group,with statistically significant differ-ences(P<0.05).There was a statistically significant difference in BMI between the two groups at 6 months after the intervention(P<0.05).The TC levels in the intervention group at 3 and 6 months after the intervention were lower than those in the control group,with statistically significant differences(P<0.05).The HDL-C level in the intervention group at 6 months after the intervention was high-er than that in the control group,with a statistically significant difference(P<0.05).The LDL-C levels in the intervention group at 1-,3-,and 6-month after the intervention were lower than those in the control group,with statistically significant differences(P<0.05).There were no statistically significant differences in TG levels between the intervention group and the control group at different time points after the intervention(P>0.05).Conclusion The behavior change intervention pro-gram based on the multiple-theory model can effectively improve and maintain healthy behaviors and improve blood lipid levels in patients with dyslipidemic ischemic stroke.
6.Correlation between serum Gal-3,FGF-21 and lung function and mMRC score in patients with COPD
Weiwei CHEN ; Mengmeng GAO ; Yue LIU ; Jing XU ; Fengyuan ZHU ; Fei LI ; Meiru FAN ; Yongqing HE
International Journal of Laboratory Medicine 2025;46(10):1212-1215
Objective To investigate the correlation between serum galectin-3(Gal-3),fibroblast growth factor-21(FGF-21)and the lung function and and the Modified British Medical Research Council dyspnea in-dex(mMRC)score in invalids with chronic obstructive pulmonary disease(COPD).Methods A total of 79 patients with COPD who received treatment in the hospital from April 2021 to April 2023 were selected as the observation group,and 60 healthy individuals in the hospital during the same period were selected as control group.The expressions of Gal-3 and FGF-21 in serum were detected and compared.The first second forced ex-piratory volume(FEV1),FEV1/forced vital capacity(FVC)and mMRC score in two groups were compared,and the correlation between the expression levels of Gal-3 and FGF-21 and FEV1,FEV1/FVC and mMRC score in COPD patients was analyzed.Results The expression levels of serum Gal-3 and FGF-21 in the obser-vation group were higher than those in the control group(P<0.05).The pulmonary function indexes in ser-um of observation group were higher than those in the control group,while the mMRC score was lower than that in the control group(P<0.05).The expression levels of Gal-3 and FGF-21 were positively correlated with FEV1 and FEV1/FVC(P<0.05),was negatively correlated with mMRC score(P<0.05).Conclusion The expression of serum Gal-3 and FGF-21 in COPD invalids is abnormal,and the expression levels of serum Gal-3 and FGF-21 in COPD patients were correlated with FEV1,FEV1/FVC and mMRC score,which could be used as important reference indicators for diagnosis and disease evaluation of COPD.
7.Progress in trauma-informed care education research abroad
Lingxiao HE ; Meiru CHEN ; Juan LÜ ; Ying DU ; Dengbin LIAO
Chinese Journal of Medical Education Research 2025;24(2):250-255
Trauma-informed care is a model of care in which healthcare professionals implement targeted interventions based on fully understanding of patients' trauma experiences, aiming to reduce psychological trauma symptoms, prevent re-traumatization, and improve health outcomes. Since the introduction of this concept, it has been applied in various fields, including medical education, mental health, obstetrics, and emergency care. The implementation of trauma-informed care requires targeted education and training for healthcare professionals; however, there is currently insufficient understanding of trauma-informed care among these professionals. Additionally, there are significant variations in the scope, content, model, and effectiveness of trauma-informed care education. This study aims to review the existing state of trauma-informed care education internationally, identify current research hotspots and shortcomings, and provide references for the future design and implementation of trauma-informed care education in China.
8.Application value of assisted compressed sensing combined with deep reconstruction in MR abdominal T2WI
Yonghui XIAO ; Dongming LIAO ; Ruxin TANG ; Meiru WEN ; Ailin CHEN
Journal of Practical Radiology 2025;41(4):678-682
Objective To analyze the application value of assisted compressed sensing(ACS)combined with deep reconstruction(DR)(ACS+DR)algorithm in MR abdominal T2WI.Methods A total of 60 patients were prospectively selected to undergo three types of respiratory-triggered transverse T2 sequence scans:fast spin echo(FSE),propeller scanning(ARMS),and ACS+DR.Two radiologists independently evaluated the images for respiratory motion artifacts,gastrointestinal peristalsis artifacts,sharpness of intrahepatic vessel and bile duct,lesion clarity,and overall image quality.Additionally,the signal-to-noise ratio(SNR),contrast-to-noise ratio(CNR),and contrast ratio(CR)between lesions and liver parenchyma signal intensity were calculated.Wilcoxon and independent sample Mann-Whitney U tests were used to compare objective scores and subjective evaluations among different groups.Results The scan time for the ACS+DR sequence was 35 s,for the ARMS sequence 180 s,and for the FSE sequence 210 s.The ACS+DR sequence showed superior performance over the other sequences in terms of scan time,respiratory motion artifacts,intrahepatic vessel and bile duct sharpness,lesion clarity,and overall image quality(P<0.05).Compared with FSE sequence,the ARMS and ACS+DR sequences exhibited higher SNR,CNR,and CR(P<0.05).The ACS+DR sequence showed better SNR and CNR than the ARMS sequence(P<0.05);however,there was no significant difference between the two sequences in CR(P>0.05).No significant difference was found among the three sequences in the number of detected lesions(P>0.05).Conclusion The ACS+DR reconstruction algorithm for upper abdominal imaging not only ensures high image quality but also significantly improves scan speed,making it valuable for clinical application.
9.Mechanisms involved in PERK-dependent autophagy under arsenite exposure
Shuxian ZOU ; Meiru HU ; Chen XING ; Lun SONG
Military Medical Sciences 2017;41(5):342-345
Objective To explore whether PERK is involved in the regulation of arsenite-induced autophagy.Methods Human hepatoma cells HepG2 were cultured and treated with arsenite.The expression level of autophagic hallmarks and the activation status of PERK were detected by Western blotting.The transactivation of p53 and the induction of its downstream target genes expression were also detected by Western blotting after knockdown of PERK expression.Transactivity of p53 was detected by dual luciferase reporter assay after knockdown of PERK expression.Results An increase in the LC3BII:I ratio,the induction of Beclin-1 expression and the degradation of p62 were readily observed in arsenite-treated HepG2 cells,but the effects were abolished after knockdown of PERK expression.Furthermore,phosphorylation of p53 at Ser15 and Ser392,transactivation of p53 and the induction of its downstream target gene DAPK1 expression were effectively inhibited under the same PERK knockdown conditions.Conclusion PERK regulates arsenite-induced autophagy by activating p53-dependent DAPK1 upregulation.
10.Nursing strategies of casualty treatment in huge blast
Meiru LI ; Shengkai SUN ; Xiaochu CHEN ; Yongzhong ZHANG ; Yahong HOU ; Xinxing MENG ; Bin CHENG
Chinese Journal of Hospital Administration 2016;32(5):346-348
This article reviewed the measures taken by the hospital against a catastrophic fire hazard and exploration in its response and work organization of nursing care of the wounded.Proposed in this paper are development of such five systems as the pre-plan,exercises,personnel,quality control and incentives,which are expected to improve the nursing capacity of the hospital in emergency rescue,for sustainable development of nursing emergency rescue work.

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