1.Meige syndrome with dyspnea as main manifestation: a report of one case and literature review.
Ting LIU ; Jinkun XU ; Jingying YE
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(10):976-979
Meige syndrome is a focal dystonic movement disorder characterized by blepharospasm and oromandibular dystonia. It is a very rare disease. Individuals affected by Meige syndrome usually experience a wide array of complex symptoms including involuntary blinking and spasms of the jaw muscle. Dyspnea is rarely mentioned, due to dystonic spasm affecting the respiratory muscles. We report a case of a 69-year-old man with Meige syndrome, with dyspnea as the main clinical manifestation. Management often involves medications, botulinum toxin injections, and surgery to alleviate symptoms and enhance function. Now we reviewed the relevant literatures and summarized the experience of diagnosis and treatment in Meige syndrome.
Humans
;
Male
;
Aged
;
Dyspnea/etiology*
;
Meige Syndrome/diagnosis*
2.Ovarian Granulosa Cell Tumor presenting as Meigs' Syndrome with elevated CA125.
Kwon CHOI ; Hyun Jong LEE ; Ji Cheul PAE ; Suk Joong OH ; Seong Yong LIM ; Eun Yoon CHO ; Seung Sei LEE
The Korean Journal of Internal Medicine 2005;20(1):105-109
Herein, a rare case of ovarian granulosa cell tumor, presenting as Meigs' syndrome, with elevated carbohydrate antigen 125 (CA125), is reported. A 69-year-old woman was admitted for the investigation of abdominal fullness and dyspnea. A preoperative examination revealed a huge pelvic tumor and an abdominopelvic magnetic resonance image (MRI) assumed ovarian cancer. A chest computed tomography (CT) scan revealed pleural effusion. A laparotomy confirmed the huge mass to be an ovarian tumor. A total abdominal hysterectomy (TAH), with a bilateral salpingo-oophorectomy (BSO) and partial omentectomy, was performed. Although short-term intrathoracic drainage was required, the hydrothorax and ascites rapidly resolved in the postoperative period.
Aged
;
CA-125 Antigen/*blood
;
Diagnosis, Differential
;
Female
;
Granulosa Cell Tumor/*diagnosis
;
Humans
;
Meige Syndrome/*diagnosis
;
Ovarian Neoplasms/*diagnosis

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