OBJECTIVE: To compare the clinical efficacy of electroacupuncture (EA) at neuro-arterial stimulation points with topical western medication in treating post-stroke shoulder-hand syndrome (SHS). METHODS: A total of 72 patients with post-stroke SHS were randomly assigned to an observation group (n=36, 2 cases dropped out) and a control group (n=36, 3 cases dropped out). Both groups received standard neurological treatment, comprehensive rehabilitation, and physical therapy. The observation group received EA at neuro-arterial stimulation points, including the ipsilateral stellate ganglion point, vagus nerve trunk and auricular branch (left side), and stimulation points of the radial and ulnar arteries, radial nerve, ulnar nerve, and median nerve, once daily for 4 weeks. The control group was treated with topical diclofenac diethylamine emulgel, and mucopolysaccharide polysulfate cream was added for patients with pronounced early-stage edema, twice a day for 4 weeks. The VAS pain score and hand edema volume were recorded before treatment, at 2 and 4 weeks during treatment, and 2 weeks after treatment completion (follow-up). Musculoskeletal ultrasound was used to measure the thickness of the dorsal hand and middle finger skin on the affected side before and after 4 weeks of treatment. RESULTS: Compared before treatment, the VAS pain scores and edema volume of the affected hand in both groups were decreased at week 2, week 4, and follow-up (P<0.05). At week 4, both groups showed lower VAS pain scores and edema volume than those at week 2 (P<0.05); during follow-up, both VAS pain scores and edema volume were further reduced compared to those at week 4 (P<0.05). At week 2, week 4, and follow-up, the VAS scores and edema volume of the affected hand in the observation group were lower than those in the control group (P<0.05). Compared before treatment, the dorsal hand skin thickness and middle finger skin thickness on the affected side were decreased in both groups after 4 weeks of treatment (P<0.05). Compared with the control group, the observation group showed thinner dorsal hand and middle finger skin thickness after 4 weeks of treatment (P<0.05). CONCLUSION EA at neuro-arterial stimulation points effectively alleviates pain and edema in patients with post-stroke SHS, and demonstrates superior efficacy compared to topical western medication.
Humans ; Male ; Female ; Middle Aged ; Electroacupuncture ; Aged ; Stroke/complications* ; Acupuncture Points ; Adult ; Reflex Sympathetic Dystrophy/physiopathology* ; Treatment Outcome ; Hand

Irritable bowel syndrome （IBS） is a functional gastrointestinal disease， but it often causes extreme gastrointestinal discomfort and prolonged illness， which seriously affects the quality of life of patients. The global incidence rate is increasing year by year. Clinically， western medicine mainly uses oral antispasmodics， secretagogues， and antidepressants， but there are many disadvantages such as adverse reactions and poor long-term efficacy. Therefore， finding an efficient and safe treatment method is an urgent problem to be solved. A large number of studies have shown that traditional Chinese medicine has definite curative and long-lasting effects on the treatment of IBS， which has become a hot research direction in recent years. By searching Chinese and foreign literature， it is found that electroacupuncture， moxibustion， Chinese medicine monomers， and compound decoctions are the main methods in the mechanism research of traditional Chinese medicine in the treatment of IBS-related pathways， and their signaling pathways involve nuclear transcription factor kappa B （NF-κB）， transient receptor potential vanillin subfamily 1 （TRPV1）， 5-hydroxytryptamine （5-HT）， mitogen-activated protein kinase （MAPK）， and so on. Traditional Chinese medicine can repair intestinal inflammation， reduce visceral sensitivity， enhance intestinal mucosal barrier， and regulate intestinal motility by regulating this series of signaling pathways， thereby playing an important role in the treatment of IBS with multi-level， multi-link and multi-target characteristics. Based on the cell signaling pathways， this paper reviewed the research progress on the mechanism of traditional Chinese medicine in the treatment of IBS， hoping to provide theoretical support and diagnosis and treatment ideas for the clinical treatment of IBS with traditional Chinese medicine.

【Objective】 To explore the factors influencing newborn birth weight under the universal two-child policy in Xi’an so as to provide information for maternal health. 【Methods】 For this study we selected the mothers who delivered babies at Xi’an Northwest Women’s and Children’s Hospital from May 2018 to November 2019. Their data included maternal demographic characteristics， delivery mode， and infants’ outcomes. Single factor analysis and multi-factor linear regression methods were used to analyze the factors influencing the birth weight of newborns of different age and mothers’ parity after the universal two-child policy. 【Results】 The newborns’ average birth weight was （3 377±449） g. The incidence of low birth weight and macrosomia was 7.4% and 2.5%， respectively. Multivariate linear regression analysis showed that gestational week of delivery （β=0.322， P<0.001）， gender （β=0.135， P<0.001）， pre-pregnancy BMI （β=0.148， P<0.001）， weight gain during pregnancy （β=0.144， P<0.001） all affected the birth weight of the newborns. In addition， in the dummy variable group， the birth weight of second-born mothers of right age （β=0.115， P<0.001） and second-born mothers （β=0.077， P=0.001） were significantly higher in elder age group than in the primipara of right age group （P<0.05）. The birth weight of the primipara in elder age group did not significantly differ from that of the primipara in right age group （P>0.05）. 【Conclusion】 Maternal women should do a good job in pre-pregnancy assessment， control pre-pregnancy weight， and gain reasonable weight during pregnancy. The community and hospitals should strengthen pre-pregnancy health education so as to scientifically and effectively improve maternal and infant outcomes.

Objective To quantitatively analyze the difference in retinal thickness of the macular outer nuclear layer (ONL) between high myopia patients and normal subjects using spectral-domain optical coherence tomography (SD-OCT). Methods Seventy-eight participants (78 eyes) were divided into normal control group and high myopia group, according to the spherical equivalent (SE) of each eye. There were 24 cases (24 eyes) in the normal control group (-0. 25 D ～+0. 25 D) and 54 cases (54 eyes) in the high myopia group(SE＜-6. 00 D). The macular retina was scanned using the posterior pole asymmetry analysis mode of the Heidelberg Spectralis (SD-OCT) system and divided into 9 areas according to Early Treatment of Diabetic Retinopathy Study. Quantitative analysis was performed to compare the difference in retinal thickness of the macular ONL in each area between the high myopia and normal control groups. Results The ONL thickness in the central area of the macular retina was significantly higher than that in the superior, nasal, inferior, and temporal areas (P ＜ 0. 001 for all comparisons). The ONL thickness in the inferior area of the macular retina was significantly lower than that in the central, superior, nasal, and temporal areas (P ＜ 0. 001 for all comparisons). In other sub-regions, no difference in the ONL thickness was found. The ONL thickness in the central, superior, nasal, inferior, and temporal areas was significantly lower in the high myopia group than in the normal control group (P ＜ 0. 05 for all comparisons). Conclusion Regional variation is observed in the ONL thickness. The ONL thickness in the macular area of patients with high myopia is thinner.

Objective: To study Bacterial Endotoxins Test(BET) for Herbe Houttuyniae Injection.Methods: The interfering test for Herbe Houttuyniae Injection was carried out. Results: The test wasn't interfered when TAL(0.25EU/ml) was used and sample was diluted in a ratio of 1 to 4.Conclusions: The BET may replace the rabbit pyrogen test.