1.Changes of peripheral hemogram of the personnel in radar troops under magnetic field effects
Suqin CHENG ; Shaoquan SUN ; Meicai ZHU
Chinese Journal of Aerospace Medicine 2017;28(4):282-286
Objective To explore the effects of magnetic field on peripheral blood by comparing the peripheral hemogram of the soldiers and officers of radar troops and the personnel in physical examination.Methods One hundred and eighty-nine soldiers and officers of radar stations whose average age was (23.2±3.5) yr,radar working experience was more than 2 years and the habitation was in radiation area without any special protection measures,were selected as test group.Other 53 soldiers and officers who were received physical examination in Air Force General Hospital were selected as control group.Their average age was (21.3 ± 2.6) yr and they had no history of electromagnetic radiation exposure.The blood routine examination was done for 2 groups to compare and analyze the effects of magnetic field on peripheral blood.Results ① The abnormal rate of peripheral blood of test group was 60.90%.The hematocrit,mean corpuscular volume,mean corpuscular hemoglobin,mean platelet volume,red blood cell distribution width,lymphocyte,lymphocyte count was respectively higher than normal value,but the neutrophilic granulocyte was lower than normal value.The higher abnormal rate of lymphocyte,hematocrit,mean platelet volume,neutrophilic in test group was respectively 39.68%,21.69%,17.46%,17.46%.The abnormal rate of hematocrit and lymphocyte of control group was respectively 3.77% and 5.66%.②The values of hematocrit,mean corpuscular volume,mean corpuscular hemoglobin,red blood cell distribution width,lymphocyte,lymphocyte count,eosinophil granulocyte,eosinophil granulocyte count,platelet hematocrit,mean platelet volume and platelet distribution width of test group were higher than those of control group (P<0.05).The values of mean corpuscular hemoglobin concentration,neutrophilic and neutrophilic count were lower than those of control group (P < 0.05).Collusions The magnetic field environment has resulted in a certain impact on the peripheral blood of the soldiers and officers of radar troops.Active protective measures should be taken to protect magnetic radiation.
2.Analysis of immunoglobulin and complement levels detected in pilots
Suqin CHENG ; Shaoquan SUN ; Kefeng LI ; Hongxia ZHENG ; Meicai ZHU
Chinese Journal of Aerospace Medicine 2017;28(1):19-22
Objective To study the change law of immunoglobulin (Ig) (IgG,IgA,IgM) and complement levels (C3,C4) in the peripheral blood of pilots by quantitative detection and to suggest the preventive measures.Methods IMMAGE800 instrument was used to detect the immunoglobulin and complement levels in 383 active pilots and 100 ground crews.Pilots were divided into bomber,transporter,helicopter and fighter groups by aircraft type.The ground crews were chosen as control group.Results Comparing to the control group,pilots showed lower peripheral blood IgG and IgM but higher C3 and C4 levels.Bomber group had lower IgG and higher C3 and C4 levels (P<0.05).Transporter group had lower IgG and IgM but higher C3 and C4 levels (P<0.05).Helicopter group showed lower IgG and IgM but higher C4 level (P<0.05).Fighter group showed lower IgG but higher C3 and C4 levels (P<0.05).Conclusions The changes on immunoglobulin and complement levels indicate the certain harmful effects on pilot's immune system.The environment factors may be the main reason led to pilot's lower IgG and IgM but higher C3 and C4 levels.The prevention of electromagnetic radiation in flight should be strengthened as the basic measures for maintaining pilot's immune functions.
3.Changes of peripheral hemogram of the personnel in radar troops under magnetic field effects
Suqin CHENG ; Shaoquan SUN ; Meicai ZHU
Chinese Journal of Aerospace Medicine 2017;28(4):282-286
Objective To explore the effects of magnetic field on peripheral blood by comparing the peripheral hemogram of the soldiers and officers of radar troops and the personnel in physical examination.Methods One hundred and eighty-nine soldiers and officers of radar stations whose average age was (23.2±3.5) yr,radar working experience was more than 2 years and the habitation was in radiation area without any special protection measures,were selected as test group.Other 53 soldiers and officers who were received physical examination in Air Force General Hospital were selected as control group.Their average age was (21.3 ± 2.6) yr and they had no history of electromagnetic radiation exposure.The blood routine examination was done for 2 groups to compare and analyze the effects of magnetic field on peripheral blood.Results ① The abnormal rate of peripheral blood of test group was 60.90%.The hematocrit,mean corpuscular volume,mean corpuscular hemoglobin,mean platelet volume,red blood cell distribution width,lymphocyte,lymphocyte count was respectively higher than normal value,but the neutrophilic granulocyte was lower than normal value.The higher abnormal rate of lymphocyte,hematocrit,mean platelet volume,neutrophilic in test group was respectively 39.68%,21.69%,17.46%,17.46%.The abnormal rate of hematocrit and lymphocyte of control group was respectively 3.77% and 5.66%.②The values of hematocrit,mean corpuscular volume,mean corpuscular hemoglobin,red blood cell distribution width,lymphocyte,lymphocyte count,eosinophil granulocyte,eosinophil granulocyte count,platelet hematocrit,mean platelet volume and platelet distribution width of test group were higher than those of control group (P<0.05).The values of mean corpuscular hemoglobin concentration,neutrophilic and neutrophilic count were lower than those of control group (P < 0.05).Collusions The magnetic field environment has resulted in a certain impact on the peripheral blood of the soldiers and officers of radar troops.Active protective measures should be taken to protect magnetic radiation.
4.Analysis of immunoglobulin and complement levels detected in pilots
Suqin CHENG ; Shaoquan SUN ; Kefeng LI ; Hongxia ZHENG ; Meicai ZHU
Chinese Journal of Aerospace Medicine 2017;28(1):19-22
Objective To study the change law of immunoglobulin (Ig) (IgG,IgA,IgM) and complement levels (C3,C4) in the peripheral blood of pilots by quantitative detection and to suggest the preventive measures.Methods IMMAGE800 instrument was used to detect the immunoglobulin and complement levels in 383 active pilots and 100 ground crews.Pilots were divided into bomber,transporter,helicopter and fighter groups by aircraft type.The ground crews were chosen as control group.Results Comparing to the control group,pilots showed lower peripheral blood IgG and IgM but higher C3 and C4 levels.Bomber group had lower IgG and higher C3 and C4 levels (P<0.05).Transporter group had lower IgG and IgM but higher C3 and C4 levels (P<0.05).Helicopter group showed lower IgG and IgM but higher C4 level (P<0.05).Fighter group showed lower IgG but higher C3 and C4 levels (P<0.05).Conclusions The changes on immunoglobulin and complement levels indicate the certain harmful effects on pilot's immune system.The environment factors may be the main reason led to pilot's lower IgG and IgM but higher C3 and C4 levels.The prevention of electromagnetic radiation in flight should be strengthened as the basic measures for maintaining pilot's immune functions.
5.Population Distribution and Incidence Analyses of Hyperuricemia in Zhoushan Island
Yinghong AN ; Yuhai WENG ; Youyi CHEN ; Yujin XU ; Hongyu MA ; Meicai ZHU
Journal of Modern Laboratory Medicine 2016;31(3):102-104,107
Objective To investigate the distribution and incidence of hyperuricemia for the Zhoushan island residents in Zhe-jiang province and provide scientific advice for health management.Methods The uric acid reports of island residents were analyzed by a retrospective statistical analysis in the Physical Examination Center of the 413 Hospital from October 2013 to October 2015.The patients with metabolic diseases (such as diabetes,chronic renal failure and other people,etc.)were ex-cluded.According to the different gender and different age groups,the average level of uric acid,hyperuricemia occurrence rate and the difference among the groups were performed statistical analyses.The single factor analysis of variance was used by Microsoft 2003 Excel software.Results The average serum uric acid level of 7 310 island residents was 283±82μmol/L and the incidence of hyperuricemia was 21.2%.The incidence of hyperuricemia was 33.6% in 31~40 years group,and the average level of uric acid was 343±86μmol/L and significantly higher than≤30 years group,significant statistic difference were observed.The incidence of hyperuricemia was more than 15% in≥41 years group,significantly higher than≤30 years group.The population of physical examination was concentrated in the 31~40 years group.The hyperuricemia incidence was 27.9% in 5 214 male residents,and the average serum uric acid level was 368±74μmol/L and higher than the female group (P<0.001).The hyperuricemia incidence was as high as 43.1% in 31~40 years group.But the level of average serum uric acid showed no significant difference with≤30 years group(P>0.05).The level of average serum uric acid level was less in≥61 and 41~50 years group than in ≤30 years group (P<0.05),but the hyperuricemia incidence were higher than ≤30 years group.The incidence of hyperuricemia was 4.6% in 2 096 female residents.The level of average serum uric acid was 257±57μmol/L and lower than the male group in all age groups (P<0.001).The incidence of hyperuricemia was 18.6% in≥60 years old and lower than 10% in the other groups.The incidence of hyperuricemia increased gradually with age.Conclu-sion The hyperuricemia incidence in island residents was higher,and higher in male than in female.The occurrence of hype-ruricemia was significantly younger.Therefore,health education,reasonable diet adj ustment,improvement of lifestyle and eating habits etc.Should be conducted for a long time to prevent the occurrence of hyperuricemia and related diseases.
6.Analysis on concentrations of serum lipids in patients with psoriasis
Juan LIU ; Lei DONG ; Ting LI ; Hongyu MA ; Meicai ZHU
International Journal of Laboratory Medicine 2015;(4):440-441
Objective To investigate the dyslipidemia in patients with psoriasis,and the characteristics of the serum lipids in pa-tients with different types of psoriasis.Methods 332 psoriatic patients were devided into pustular psoriatic,psoriasis vulgaris and erythrodermic psoriasis based on clinical manifestations.Serum lipids of the three groups were analyzed including TC,TG,HDL-C, LDL-C,ApoA1,ApoB and Lp(a).Results The serum concentrations of TC,HDL-C,ApoA1 in patients with psoriasis were signifi-cantly lower than those in control group(P <0.05),while the concentration of Lp(a)was significantly higher in psoriasis patients compared with those in control group(P <0.05).The serum level of TC,HDL-C,LDL-C and ApoA1 in pustular psoriasis group were significantly lower than those in the other two groups(P <0.05).Conclusion The patients with psoriasis have dyslipidemia, and the serious disorder situation could be associated with psoriasis types.
7.Research progress in optical imaging technology of luciferase
Lei DONG ; Juan LIU ; Hongyu MA ; Shouzhen QUAN ; Meicai ZHU
International Journal of Biomedical Engineering 2012;(6):373-376
The primary function of optical in vivo imaging technique is tracing and detecting the action and expression of maker cells,maker microorganisms and maker molecules.This technique makes possible the noinvasive study of biological events continuously with high sensibility,simplicity and high speed.It has been applied in numerous research fields.This paper presents a review of principle and application of this technique.
8.Effects of danshen and basic fibroblast growth factor on mRNA expression of inducible nitricoxide synthase mRNA in the brain of rats after repeated +Gz exposure
Hongjin LIU ; Qing CAI ; Jiandong JIANG ; Zhi ZHAN ; Meicai ZHU
Chinese Journal of Tissue Engineering Research 2006;10(27):156-157,160
BACKGROUND: +Gz-induced acute dysencephalia and its protection is one of the significant topics in Aero-medical researches. Its pathological mechanism, however, is still unclear and protective measures should be developed further. OBJECTIVE: To observe the expression of inducible nitricoxide synthase (iNOS) in brain tissue after +Gz exposure and to analyze the protective effects of danshen and basic fibroblast growth factor (bFGF) on repeated +Gz exposure-induced brain injury. DESIGN: Randomized controlled animal study. SETTING: Researching Center of Molecular Biology, Air-force General Hospital of Chinese PLA.MATERIALS: The experiment was carried out at the Researching Center of Molecular Biology, Air-force General Hospital of Chinese PLA from April to August 2000. A total of 20 healthy SD rats of clean grade were divided into 5 groups according to randomly digital table, including control group, +Gz exposure group, bFGF group, danshen group and saline group with 4 in each group.METHODS: All rats were fixed on rotatory arm of centrifugal apparatus,and their heads were towards core of the apparatus. Except the rats in control group, the value of +Gz exposure was +14 Gz, and the growth rate was 1.5 G/s. The exposure at peak value lasted for 45 s. +Gz exposure was done for three times, and the interval was 30 minutes. Rats in the control group were also treated with the same +Gz exposing procedure, but the G value was +1 Gz. Rats in bFGF group and danshen group were intraperitoneally injected with 100 μg/kg of bFGF and/or 15 g/kg of danshen solution, respectively, at 30 minutes before centrifugation and immediateness after centrifugation; moreover, rats in saline group were injected with the same volume of saline. Six hours after exposure, rats were cut off their heads to obtain the brains which were maintained in liquid nitrogen for RNA extraction. The expression of iNOS mRNA in brain tissues of the rats in each group was detected with semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) and calculated on the basis of ratio between iNOS and glyceraldehyde-3-phosphate dehydrognase.MAIN OUTCOME MEASURES:Expressed level of iNOS mRNA in brain tissue of rats.RESULTS: Expression of iNOS mRNA in brain tissue was higher in repeated +Gz exposure group than that in control group (0.452 ±0.014,0.065±0.008, P < 0.01); however, that was lower in bFGF group and dan-shen group than that in +Gz exposure group (0.196±0.010, 0.183±0.011,0.452±0.014, P < 0.01).CONCLUSION: Repeated +Gz exposure can increase the expression of iNOS mRNA, this plays an important role in cerebral injury induced by repeated +Gz exposure. Moreover, bFGF and danshen have protective effects on cerebral injury induced by +Gz exposure.
9.Identification and Clinical Analysis of Tamm-Horsfall Detection of RBC in Urine to Diabetic Nephropathy Hematuria
Hongyu MA ; Meicai ZHU ; Qing HE ; Jinli ZHOU ; Tao CHEN
Chinese Medical Equipment Journal 2003;0(10):-
70% for 9 patients;the positive rate was between 30-70% for 4 patients;the positive rate 0.05). Conclusion Tamm-Horsfall detection of RBC in urine could be used as one of the Identification indicators for DN hematuria, and it can provide a basis for diagnosis and treatment of DN.
10.Application of microimmunofluorescence test and PCR in the diagnosis of acute Chlamydia pneumoniae infections
Jianbiao LI ; Qing CAI ; Ying WANG ; Jianzhong ZHAO ; Qing DUAN ; Shuguo JI ; Meicai ZHU
Journal of Third Military Medical University 2001;23(4):459-461
Objective To explore the role of acute infection of Chlamydia pneumoniae (Cpn) in respiratory diseases. Methods Microimmunofluorescence test was used to detect IgG antibodies for Cpn in serum obtained from 93 inpatients and PCR was used to test Cpn in detection of Cpn DNA in throat specimens from 55 of the 99 patients. Results Acute Cpn infection was diagnosed in 35.5% of the respiratory diseases. Antibodies for Cpn (titer of ≥512) were present in 47.6% of the pneumonia group, which may suggest that during 1998 to 1999, Cpn caused an epidemic in Beijing. They were also present in 50% of asthma group, 50.0% of pulmonary heart disease group and 26.3% of lung cancer group. Only five patients (9.1%) were positive by PCR. There exists discrepancy between serological and PCR results. Conclusion Detection of IgG antibodies for Cpn conduces to diagnosis of acute Cpn infection and give advice for appropriate therapy.

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