1.Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh
Syed Ishtiaque HOSSAIN ; Rapty SARKER ; Sardar Mohammad ASHRAFUL ISLAM ; Mohiuddin Ahmed BHUIYAN ; MMA Shalahuddin QUSAR ; Md. Rabiul ISLAM
Osong Public Health and Research Perspectives 2025;16(1):72-80
Objectives:
Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and environmental factors.Limited observational studies have examined cytokines in Bangladeshi patients with OCD. This study aimed to assess the levels of eotaxin-1 and interleukin (IL)-34 in individuals with this disorder.
Methods:
This case-control observational study included 58 patients with OCD and 30 healthy controls (HCs) matched for age, sex, and body mass index. The severity of OCD was assessed using the Yale-Brown obsessive-compulsive scale (Y-BOCS). Psychiatrists evaluated participants according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Serum levels of eotaxin-1 and IL-34 were measured using enzyme-linked immunosorbent assay kits.
Results:
Patients with OCD exhibited significantly higher serum eotaxin-1 levels (121.13 ± 7.84pg/mL) than HCs (85.52 ± 9.42 pg/mL). Conversely, IL-34 levels were considerably lower in patients than in HCs (119.02 ± 14.53 pg/mL vs. 179.96 ± 27.88 pg/mL). The Cohen d values for eotaxin-1 and IL-34 were 0.55 and −0.48, respectively. Among patients with OCD, a significantpositive correlation was found between serum eotaxin-1 level and Y-BOCS score, along with a negative correlation between serum eotaxin-1 and IL-34 levels.
Conclusion
The findings suggest that altered eotaxin-1 and IL-34 levels may be associated withOCD. These chemokines and cytokines could serve as primary tools for assessing the risk of OCD, warranting further clinical investigation. This could potentially support more extensive research and the development of diagnostic and therapeutic strategies targeting these pathways.
2.Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh
Syed Ishtiaque HOSSAIN ; Rapty SARKER ; Sardar Mohammad ASHRAFUL ISLAM ; Mohiuddin Ahmed BHUIYAN ; MMA Shalahuddin QUSAR ; Md. Rabiul ISLAM
Osong Public Health and Research Perspectives 2025;16(1):72-80
Objectives:
Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and environmental factors.Limited observational studies have examined cytokines in Bangladeshi patients with OCD. This study aimed to assess the levels of eotaxin-1 and interleukin (IL)-34 in individuals with this disorder.
Methods:
This case-control observational study included 58 patients with OCD and 30 healthy controls (HCs) matched for age, sex, and body mass index. The severity of OCD was assessed using the Yale-Brown obsessive-compulsive scale (Y-BOCS). Psychiatrists evaluated participants according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Serum levels of eotaxin-1 and IL-34 were measured using enzyme-linked immunosorbent assay kits.
Results:
Patients with OCD exhibited significantly higher serum eotaxin-1 levels (121.13 ± 7.84pg/mL) than HCs (85.52 ± 9.42 pg/mL). Conversely, IL-34 levels were considerably lower in patients than in HCs (119.02 ± 14.53 pg/mL vs. 179.96 ± 27.88 pg/mL). The Cohen d values for eotaxin-1 and IL-34 were 0.55 and −0.48, respectively. Among patients with OCD, a significantpositive correlation was found between serum eotaxin-1 level and Y-BOCS score, along with a negative correlation between serum eotaxin-1 and IL-34 levels.
Conclusion
The findings suggest that altered eotaxin-1 and IL-34 levels may be associated withOCD. These chemokines and cytokines could serve as primary tools for assessing the risk of OCD, warranting further clinical investigation. This could potentially support more extensive research and the development of diagnostic and therapeutic strategies targeting these pathways.
3.Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh
Syed Ishtiaque HOSSAIN ; Rapty SARKER ; Sardar Mohammad ASHRAFUL ISLAM ; Mohiuddin Ahmed BHUIYAN ; MMA Shalahuddin QUSAR ; Md. Rabiul ISLAM
Osong Public Health and Research Perspectives 2025;16(1):72-80
Objectives:
Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and environmental factors.Limited observational studies have examined cytokines in Bangladeshi patients with OCD. This study aimed to assess the levels of eotaxin-1 and interleukin (IL)-34 in individuals with this disorder.
Methods:
This case-control observational study included 58 patients with OCD and 30 healthy controls (HCs) matched for age, sex, and body mass index. The severity of OCD was assessed using the Yale-Brown obsessive-compulsive scale (Y-BOCS). Psychiatrists evaluated participants according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Serum levels of eotaxin-1 and IL-34 were measured using enzyme-linked immunosorbent assay kits.
Results:
Patients with OCD exhibited significantly higher serum eotaxin-1 levels (121.13 ± 7.84pg/mL) than HCs (85.52 ± 9.42 pg/mL). Conversely, IL-34 levels were considerably lower in patients than in HCs (119.02 ± 14.53 pg/mL vs. 179.96 ± 27.88 pg/mL). The Cohen d values for eotaxin-1 and IL-34 were 0.55 and −0.48, respectively. Among patients with OCD, a significantpositive correlation was found between serum eotaxin-1 level and Y-BOCS score, along with a negative correlation between serum eotaxin-1 and IL-34 levels.
Conclusion
The findings suggest that altered eotaxin-1 and IL-34 levels may be associated withOCD. These chemokines and cytokines could serve as primary tools for assessing the risk of OCD, warranting further clinical investigation. This could potentially support more extensive research and the development of diagnostic and therapeutic strategies targeting these pathways.
4.Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh
Syed Ishtiaque HOSSAIN ; Rapty SARKER ; Sardar Mohammad ASHRAFUL ISLAM ; Mohiuddin Ahmed BHUIYAN ; MMA Shalahuddin QUSAR ; Md. Rabiul ISLAM
Osong Public Health and Research Perspectives 2025;16(1):72-80
Objectives:
Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and environmental factors.Limited observational studies have examined cytokines in Bangladeshi patients with OCD. This study aimed to assess the levels of eotaxin-1 and interleukin (IL)-34 in individuals with this disorder.
Methods:
This case-control observational study included 58 patients with OCD and 30 healthy controls (HCs) matched for age, sex, and body mass index. The severity of OCD was assessed using the Yale-Brown obsessive-compulsive scale (Y-BOCS). Psychiatrists evaluated participants according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Serum levels of eotaxin-1 and IL-34 were measured using enzyme-linked immunosorbent assay kits.
Results:
Patients with OCD exhibited significantly higher serum eotaxin-1 levels (121.13 ± 7.84pg/mL) than HCs (85.52 ± 9.42 pg/mL). Conversely, IL-34 levels were considerably lower in patients than in HCs (119.02 ± 14.53 pg/mL vs. 179.96 ± 27.88 pg/mL). The Cohen d values for eotaxin-1 and IL-34 were 0.55 and −0.48, respectively. Among patients with OCD, a significantpositive correlation was found between serum eotaxin-1 level and Y-BOCS score, along with a negative correlation between serum eotaxin-1 and IL-34 levels.
Conclusion
The findings suggest that altered eotaxin-1 and IL-34 levels may be associated withOCD. These chemokines and cytokines could serve as primary tools for assessing the risk of OCD, warranting further clinical investigation. This could potentially support more extensive research and the development of diagnostic and therapeutic strategies targeting these pathways.
5.Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh
Syed Ishtiaque HOSSAIN ; Rapty SARKER ; Sardar Mohammad ASHRAFUL ISLAM ; Mohiuddin Ahmed BHUIYAN ; MMA Shalahuddin QUSAR ; Md. Rabiul ISLAM
Osong Public Health and Research Perspectives 2025;16(1):72-80
Objectives:
Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and environmental factors.Limited observational studies have examined cytokines in Bangladeshi patients with OCD. This study aimed to assess the levels of eotaxin-1 and interleukin (IL)-34 in individuals with this disorder.
Methods:
This case-control observational study included 58 patients with OCD and 30 healthy controls (HCs) matched for age, sex, and body mass index. The severity of OCD was assessed using the Yale-Brown obsessive-compulsive scale (Y-BOCS). Psychiatrists evaluated participants according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Serum levels of eotaxin-1 and IL-34 were measured using enzyme-linked immunosorbent assay kits.
Results:
Patients with OCD exhibited significantly higher serum eotaxin-1 levels (121.13 ± 7.84pg/mL) than HCs (85.52 ± 9.42 pg/mL). Conversely, IL-34 levels were considerably lower in patients than in HCs (119.02 ± 14.53 pg/mL vs. 179.96 ± 27.88 pg/mL). The Cohen d values for eotaxin-1 and IL-34 were 0.55 and −0.48, respectively. Among patients with OCD, a significantpositive correlation was found between serum eotaxin-1 level and Y-BOCS score, along with a negative correlation between serum eotaxin-1 and IL-34 levels.
Conclusion
The findings suggest that altered eotaxin-1 and IL-34 levels may be associated withOCD. These chemokines and cytokines could serve as primary tools for assessing the risk of OCD, warranting further clinical investigation. This could potentially support more extensive research and the development of diagnostic and therapeutic strategies targeting these pathways.
6.Isolation and identification of aerobic and anaerobic bacteria from the feces of wild Korean water deer (Hydropotes inermis argyropus)
Md Ashraful ISLAM ; Sungryong KIM ; Md Sodrul ISLAM ; Obaidul ISLAM ; Seunghyeon PARK ; Itainara TAILI ; Dong-Hyuk JEONG ; Ki-Jeong NA
Journal of Veterinary Science 2024;25(6):e78-
Objective:
This study aims to isolate and identify aerobic and anaerobic bacterial species in the feces of wild KWD.
Methods:
Fecal samples were collected from 55 wild KWD of varying age and sex.Aerobic bacteria were cultured at 37°C for 24–48 h under standard conditions, whereas anaerobic bacteria were cultured at 37°C for 48–72 h in an anaerobic environment. Bacterial identification was conducted using DNA extraction and polymerase chain reaction amplification targeting the 16S rRNA gene.
Results:
The predominant aerobic bacteria identified belonged to the Firmicutes (58.18%) and Proteobacteria (41.82%) phyla, with Escherichia coli (31.82%) and Bacillus cereus (31.82%) being the most common species. Among anaerobic bacteria, most belonged to the Firmicutes (71.03%), Proteobacteria (27.10%), and Fusobacteriota (1.87%) phyla, with Paraclostridium bifermentans (28.97%) and E. coli (22.43%) being the most prevalent species.Other frequently identified anaerobic species were Fusobacterium varium, Lactococcus garvieae, Terrisporobacter glycolicus, Enterococcus faecalis, and Clostridium sporogenes.
Conclusions
and Relevance: Our findings indicate a diverse microbial community in the feces of water deer, offering valuable insights into their gut microbiota and its potential implications for health and ecology.
7.Isolation and identification of aerobic and anaerobic bacteria from the feces of wild Korean water deer (Hydropotes inermis argyropus)
Md Ashraful ISLAM ; Sungryong KIM ; Md Sodrul ISLAM ; Obaidul ISLAM ; Seunghyeon PARK ; Itainara TAILI ; Dong-Hyuk JEONG ; Ki-Jeong NA
Journal of Veterinary Science 2024;25(6):e78-
Objective:
This study aims to isolate and identify aerobic and anaerobic bacterial species in the feces of wild KWD.
Methods:
Fecal samples were collected from 55 wild KWD of varying age and sex.Aerobic bacteria were cultured at 37°C for 24–48 h under standard conditions, whereas anaerobic bacteria were cultured at 37°C for 48–72 h in an anaerobic environment. Bacterial identification was conducted using DNA extraction and polymerase chain reaction amplification targeting the 16S rRNA gene.
Results:
The predominant aerobic bacteria identified belonged to the Firmicutes (58.18%) and Proteobacteria (41.82%) phyla, with Escherichia coli (31.82%) and Bacillus cereus (31.82%) being the most common species. Among anaerobic bacteria, most belonged to the Firmicutes (71.03%), Proteobacteria (27.10%), and Fusobacteriota (1.87%) phyla, with Paraclostridium bifermentans (28.97%) and E. coli (22.43%) being the most prevalent species.Other frequently identified anaerobic species were Fusobacterium varium, Lactococcus garvieae, Terrisporobacter glycolicus, Enterococcus faecalis, and Clostridium sporogenes.
Conclusions
and Relevance: Our findings indicate a diverse microbial community in the feces of water deer, offering valuable insights into their gut microbiota and its potential implications for health and ecology.
8.The Global Research Trends on Food Waste At Healthcare Setting: A Bibliometric Analysis Using Scopus Database
Nurul Alia Aqilah Samiun ; Nurul Huda Razalli ; Suzana Shahar ; Zahara Abdul Manaf ; Zurina Kefeli ; Jauharah Md Khudzari ; Norshariza Jamhuri
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):312-322
The issue of food waste has garnered much attention globally due to its adverse impacts on the economy, food security, natural resources, the environment, and human health. Despite this, the academic literature lacks systematic,
historical, and synthesising investigations on healthcare food waste. This bibliometrics analysis study aims to summarise the growing trends of food waste publications and highlight common and potential research topics of food
waste in healthcare settings. The Scopus database analysed 193 journal articles published between 1952 and 2022.
We identified several common and potential research topics for future research in the area, including food waste and
malnutrition, related intervention strategies, the impact of healthcare food service systems on food waste, and their
economic and environmental impact. Healthcare food waste research in developing nations is still limited. Thus, it
is recommended that policymakers support its development as one of the steps to encounter food waste.
9.The Impact of COVID-19 on Healthcare Services in Bangladesh: A Qualitative Study on Healthcare Providers’ Perspectives
Sharmin PARVEEN ; Md. Shahriar MAHBUB ; Nasreen NAHAR ; K. A. M. MORSHED ; Nourin RAHMAN ; Ezzat Tanzila EVANA ; Nazia ISLAM ; Abu Said Md. Juel MIAH
Journal of Preventive Medicine and Public Health 2024;57(4):356-369
Objectives:
The objective of this study was to explore healthcare providers’ experiences in managing the coronavirus disease 2019 (COVID-19) pandemic and its impact on healthcare services.
Methods:
A qualitative study was conducted with 34 healthcare professionals across 15 districts in Bangladesh. Among the participants, 24 were health managers or administrators stationed at the district or upazila (sub-district) level, and 10 were clinicians providing care to patients with COVID-19. The telephone interviews were conducted in Bangla, audio-recorded, transcribed, and then translated into English. Data were analyzed thematically.
Results:
Most interviewees identified a range of issues within the health system. These included unpreparedness, challenges in segregating COVID-19 patients, maintaining isolation and home quarantine, a scarcity of intensive care unit beds, and ensuring continuity of service for non-COVID-19 patients. The limited availability of personal protective equipment, a shortage of human resources, and logistical challenges, such as obtaining COVID-19 tests, were frequently cited as barriers to managing the pandemic. Additionally, changes in the behavior of health service seekers, particularly increased aggression, were reported. The primary motivating factor for healthcare providers was the willingness to continue providing health services, rather than financial incentives.
Conclusions
The COVID-19 pandemic presented a unique set of challenges for health systems, while also providing valuable lessons in managing a public health crisis. To effectively address future health crises, it is crucial to resolve a myriad of issues within the health system, including the inequitable distribution of human resources and logistical challenges.
10.Isolation and identification of aerobic and anaerobic bacteria from the feces of wild Korean water deer (Hydropotes inermis argyropus)
Md Ashraful ISLAM ; Sungryong KIM ; Md Sodrul ISLAM ; Obaidul ISLAM ; Seunghyeon PARK ; Itainara TAILI ; Dong-Hyuk JEONG ; Ki-Jeong NA
Journal of Veterinary Science 2024;25(6):e78-
Objective:
This study aims to isolate and identify aerobic and anaerobic bacterial species in the feces of wild KWD.
Methods:
Fecal samples were collected from 55 wild KWD of varying age and sex.Aerobic bacteria were cultured at 37°C for 24–48 h under standard conditions, whereas anaerobic bacteria were cultured at 37°C for 48–72 h in an anaerobic environment. Bacterial identification was conducted using DNA extraction and polymerase chain reaction amplification targeting the 16S rRNA gene.
Results:
The predominant aerobic bacteria identified belonged to the Firmicutes (58.18%) and Proteobacteria (41.82%) phyla, with Escherichia coli (31.82%) and Bacillus cereus (31.82%) being the most common species. Among anaerobic bacteria, most belonged to the Firmicutes (71.03%), Proteobacteria (27.10%), and Fusobacteriota (1.87%) phyla, with Paraclostridium bifermentans (28.97%) and E. coli (22.43%) being the most prevalent species.Other frequently identified anaerobic species were Fusobacterium varium, Lactococcus garvieae, Terrisporobacter glycolicus, Enterococcus faecalis, and Clostridium sporogenes.
Conclusions
and Relevance: Our findings indicate a diverse microbial community in the feces of water deer, offering valuable insights into their gut microbiota and its potential implications for health and ecology.


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