1.Correlation of the 4-hour, 8-hour, and 12-hour urine protein values with the 24-hour proteinuria in hospitalized patients with hypertensive disorders in pregnancy.
Mary Grace Lourdes G FLORES ; Ma. Cristina PELAEZ-CRISOLOGO
Philippine Journal of Obstetrics and Gynecology 2009;33(4):117-122
Prompt diagnosis using an accurate and quick laboratory test would promote timely intervention and result in a decrease in maternal moralities caused by pregnancy induced hypertension. The 24-hour urine collection, the gold standard in diagnosing proteinuria in preeclampsia, is both tedious and time-consuming resulting to delayed management or poor compliance.
This cross-sectional study aimed to determine whether 4-hour, 8-hour and 12-hour urine protein values correlate with the 24-hour urine protein value in women with hypertensive disorders in pregnancy.
Pregnancy patients diagnosed with hypertensive disorders in pregnancy admitted at the Obstetrics Ward and Labor Room of the Philippine General Hospital who are more than 20 weeks age of gestation were included in the study. The 24-hour urine collection was modified accordingly and subdivided into the 4-,8-,12- and 24-hour collection. Total volume, total protein, and urine creatinine for the samples were obtained and the results were analyzed using the Pearson collection. Only the 4- and the 8- hour samples were found to be statistically significant variables associated with the 24-hour sample. Cut-off values for the 8-hour sample were determined to be 657 mg for severe proteinuria.
Human ; Pre-eclampsia ; Creatinine ; Urine Specimen Collection ; Hypertension, Pregnancy-induced ; Hospitals, General ; Philippines ; Proteinuria ; Urinalysis ; Kidney Function Tests
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