1.Knowledge, attitude and practice on sexually transmitted infections among men and women aged 15-24 years old in Sampaloc, Manila.
Heinze Joseph L. LOPEZ ; Kent Aldrin V. LUZARRAGA ; Christian Rafael B. LORENZO ; Paolo Jose A. LORENZO ; Yannah Mae F. LOYOLA ; Ann Danelle A. LUCERO ; Abbygale R. LUMANGLAS ; Gelza Mae ZABAT ; Jayron PADUA ; Maria Elizabeth P. MERCADO
Journal of Medicine University of Santo Tomas 2026;10(1):1904-1912
<p>In the Philippines, the rate of sexually transmitted infections (STIs) remains high, and statistics show that the highest prevalence is among individuals between the ages of 15 and 24 years old. Unlike Human Immunodeficiency Virus (HIV), other common STIs, such as gonorrhea, syphilis, HPV and herpes are not well discussed.p><p>A descriptive cross-sectional study was conducted to determine the knowledge, awareness and misconceptions of STIs and their practices among men and women aged 15-24 in Sampaloc, Manila. Convenience sampling was conducted among 15- to 24-year-old residents from Barangay 466, excluding healthcare professionals. Sets of questions were adapted from other knowledge, attitudes and practices (KAP) research studies and underwent cross-cultural validation. Questions were also translated and validated into the Filipino language. Data gathering was conducted using self-administered surveys disseminated through online posting and in-community, as well as face-to-face recruitment.p><p>Among the 104 respondents, HIV remained the most recognized STI (99%), while less than half were aware that chlamydia and hepatitis B are STIs. The most common misconception about STI transmission includes the sharing of food and drinks. In terms of prevention, more than half of the participants believed that oral contraceptive pills can prevent STIs. With regards to attitude, 43.3% of the participants disagreed that watching/reading pornographic materials can contribute to risky sexual practices. Among sexually active participants, 19% do not use condoms, and 65% of them do not get tested annually.p><p>In conclusion, the findings from this study reveal a concerning gap in KAP related to STIs among participants aged 15-24 Filipinos. It is recommended that efforts should be directed towards targeted education campaigns and interventions to empower young individuals with accurate information and foster a responsible approach to sexual health.p>
Human
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Adolescent: 13-18 Yrs Old
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Young Adult: 19-24 Yrs Old
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Surveys And Questionnaires
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Sexually Transmitted Diseases
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Residence Characteristics
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Cross-sectional Studies
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Reproductive Health
2.Virgin coconut oil as adjunctive therapy for hospitalized COVID-19 patients in a Tertiary Referral Hospital: A randomized controlled trial
Marissa M. Alejandria ; Leslie Michelle M. Dalmacio ; Fresthel Monica M. Climacosa ; Carol Stephanie C. Tan-Lim ; Mark Joseph M. Abaca ; Maria Llaine J. Callanta ; Maria Elizabeth P. Mercado
Acta Medica Philippina 2024;58(8):31-41
Background:
Virgin coconut oil (VCO) has anti-viral and anti-inflammatory properties, making it a potential therapeutic candidate against COVID-19 infection.
Objective:
To determine the efficacy and safety of VCO as adjunctive therapy for hospitalized patients with COVID-19.
Methods:
We conducted a randomized, open-label controlled trial involving laboratory-confirmed COVID-19 patients admitted at the Philippine General Hospital. The study participants were randomized to the intervention group who received virgin coconut oil with local standard of care, or to the control group who received local standard of care alone.
Results:
We enrolled 39 participants into the VCO group and 38 participants into the control group. Significantly fewer participants in the VCO group had abnormal CRP levels at the end of treatment compared to control. (relative risk [RR] 0.75, 95% confidence interval [CI] 0.58 to 0.95; p=0.02) No significant difference was found in the duration of hospital stay (mean 9.33 days for VCO vs. 10.29 days for control; p=0.45) and time to symptom resolution (mean 6.8 days for VCO, vs. 6.74 days for control; p=0.91). Although the proportion of patients who developed the secondary outcomes of mortality, need for ICU admission, need for invasive ventilation, and negative viral conversion was lower in the VCO group, results did not reach statistical significance. The VCO group had larger reduction in the inflammatory markers ferritin, lactate dehydrogenase, TNF-alpha, IP-10 and IL-6, but results did not reach statistical significance. Adverse events were significantly higher in the VCO group (RR 4.87, 95% CI 1.14 to 20.79; p=0.03).
Conclusion
This clinical trial on hospitalized patients showed significant benefit in CRP levels of participants given VCO compared to control. There was no significant benefit in the use of VCO as adjunctive therapy in reducing duration of hospital stay. Larger studies are needed to conclusively demonstrate the effect of VCO on other clinical outcomes and inflammatory markers.
COVID-19
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Clinical Trial


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