AIM: To investigate the epidemiological characteristics and changing trends of myopia among children and adolescents in Bijie from 2021 to 2025, and to provide scientific evidence for formulating regional myopia prevention and control strategies.METHODS:This was a longitudinal cross-sectional study. Stratified cluster sampling method was used to select students from 48 primary schools, 25 middle schools, and 8 high schools from urban and rural districts and counties of Bijie. From 2021 to 2025, annual examinations were performed, including uncorrected visual acuity, corrected visual acuity, corneal curvature, refractive error, axial length, and fundus examination. Questionnaires were also administered to collect information on visual health-related influencing factors. Myopia was defined as spherical equivalent refraction(SE)≤-0.50 D under non-cycloplegic autorefraction. The multivariate logistic regression model was used to analyze the myopia status and its influencing factors among children and adolescents.RESULTS: From 2021 to 2025, the age- and sex-standardized myopia prevalence rates among children and adolescents in Bijie were 42.37%, 44.57%, 47.32%, 49.98%, and 52.91%, respectively, showing a significant upward trend year by year(P<0.001). The overall standardized myopia prevalence rate was 47.61%. The myopia rate increased with higher educational stage, and the differences were statistically significant(P<0.001). The myopia rates in girls were higher than those in boys over the 5 y, with statistically significant differences(P<0.001). Multivariable logistic regression analysis identified gender(female vs male: OR=1.17, 95%CI: 1.15-1.19), school stage(junior high school vs primary school: OR=2.14, 95%CI: 2.09-2.19; senior high school vs primary school: OR=3.60, 95%CI: 3.53-3.68), daily outdoor activity time <2 h(OR=3.25, 95%CI: 2.98-3.54), both parents with myopia(OR=2.87, 95%CI: 2.63-3.13), daily near work time ≥4 h(OR=2.56, 95%CI: 2.35-2.79), electronic screen use ≥2 h/d(OR=2.18, 95%CI: 2.01-2.37), incorrect reading and writing posture(OR=3.94, 95%CI: 3.87-4.02), residence in a karst landform region(OR=1.32, 95%CI: 1.18-1.48), and absence of professional equipment in school vision screening(OR=1.27, 95%CI: 1.15-1.41)as risk factors for myopia(all P<0.001).CONCLUSION: From 2021 to 2025, the myopia rate among children and adolescents in Bijie shows an increasing trend, indicating a severe situation for myopia prevention and control, with tendencies toward younger age of onset and higher myopia. It is necessary to establish a prevention and control system led by the government, with multi-departmental collaboration and school-family linkage, and to carry out targeted health education and intervention measures.

Objective:To investigate the current situation of general practitioners' occupational pressure in Heilongjiang Province, and explore its relationship with professional identity and perceived organizational support. It aims to provide references for the construction of general practitioners and the development of general medical education.Methods:The general situation questionnaire, perceived organizational support scale, occupational pressure scale, and professional identity scale were applied through network and site surveys for collecting data. A total of 288 questionnaires were collected with 263 valid questionnaires (91.3%). Pearson correction analysis and bootstrap analysis were performed for data analysis.Results:The average score of occupational pressure among general practitioners was (115.95±22.40), and the results of Pearson correction analysis showed that perceived organizational support was negatively correlated with occupational pressure ( r=-0.413, P<0.01) and positive correlation with professional identity ( r=0.587, P<0.01). There were also significant negative correlations between professional identity and occupational pressure ( r=-0.442, P<0.01). Moreover, the mediating effect showed that professional identity had a certain mediating effect on the relationship between perceived organizational support and occupational pressure (LLCI=-0.2039, ULCI=-0.0760, P<0.05). Conclusion:General practitioners' occupational pressure was at a high level, which can be reduced through improving the perceived organizational support and professional identity.

Objective To investigate the factors affecting platelet transfusion efficiency.Methods A total of 102 cases of leuke-mia patients were recruited in the study,whose platelet count were measured before platelet transfusion and 1,24 h after platelet transfusion,then corrected count increment(CCI)values were calculated.By using CCI combined with clinical manifestations,the ef-ficacy of platelet transfusion were evaluated.The platelet antibody were detected before platelet transfusion.Depending on whether there were platelet antibodies,complications,the number of times of platelet transfusion,the types of platelet,patients were grouped and their platelet transfusion efficiency and CCI values were compared.Results The total effective rate of platelet transfusions were 71.6%(73/102 ).Invalid transfusion group had higher platelet antibody positive rate (17.2%)than effective transfusion group (2.7%),the difference were statistically significant(P <0.05).Among the groups of different transfusion times,the tansfusion effi-ciency was statistically different(P <0.05).With the increase of the number of times of platelet transfusion,the platelet transfusion efficiency decreased.Comparison between different types of platelets showed different platelet transfusion efficiency,which was sta-tistically significant(P <0.05).1 h and 24 h CCI value,platelet antibodies and whether patients with complications were related(P<0.05).1 h and 24 h CCI values were both associated with platelet antibodies and complications(P <0.05).Conclusion Platelet antibodies,complications,times of platelet transfusion and types of platelet transfusion are affecting factors of the transfusion effica-cy in patients with leukemia.