The mandibular metastatic spread of carcinoma from the thyroid gland is exceedingly rare. Follicular thyroid carcinoma is the second most common type of thyroid carcinoma，accounting for approximately 10% to 15% of all thyroid cancers. The prognosis of FTC is relatively satisfactory. Due to its rich blood transport, it is easy to metastasize hematological, with the main sites of metastasis are bone and lung. However，mandibular metastasis of thyroid follicular carcinoma is rare. We report a case of thyroid follicular carcinoma that metastasized to the ascending ramus of the mandible 21 years after surgery.The operation was successfully completed, and there was no recurrence during postoperative follow-up. Due to the absence of obvious clinical symptoms in the patient, the diagnosis and treatment were challenging. We have provided detailed radiographic and pathological images to facilitate understanding and discussion of the disease.
Humans ; Adenocarcinoma, Follicular/pathology* ; Thyroid Neoplasms/surgery* ; Prognosis ; Mandible

Pus overflow from patent's fistula belew the left face near mandibular angle 2 years agowith a little pain. Symptoms relieved after oral antibiotics. This symptom frequently occurred in the past six months. Postoperative facial paralysis occurred after surgery, and recovered after treatment. It was diagnosed as the postoperative facial paralysis after first branchial fistula surgery.
Branchial Region ; pathology ; surgery ; Face ; Facial Paralysis ; etiology ; Fistula ; pathology ; surgery ; Humans ; Mandible ; Pain

Atrophy ; Bone Transplantation ; methods ; Fracture Fixation, Internal ; Fracture Healing ; Fractures, Comminuted ; surgery ; Humans ; Mandible ; pathology ; Mandibular Fractures ; pathology ; surgery ; Surgical Wound Infection ; etiology

Bone Plates ; Bone Screws ; Fracture Fixation, Internal ; methods ; Humans ; Mandible ; pathology ; surgery ; Mandibular Fractures ; surgery ; Reconstructive Surgical Procedures ; methods

OBJECTIVECondylectomy was performed to treat condylar osteoma or hyperplasia. Introduced two methods of condylectomy via intraoral approach and evaluated their clinical results.

METHODSThirty-five patients, aging from 22 to 57.21 years, were treated by condylectomy via intraoral approach, of which 21 were condyle osteoma, 14 hemimandibular hyperplasia and condylar hyperplasia. Intraoral vertical ramus osteotomy (IVRO) were used in 32 patients and intraoral condylectomy via coronoid process resection was used in 3 patients.

RESULTSThe treatment results including oral function and facial symmetry after the operation were good in all patients. The temporomandibular joint (TMJ) dysfunction syndrome alleviated or disappeared. The follow-up period was 6 months to 3 years, and no relapse of condylar osteoma or hyperplasia was found. The patients who had IVRO and TMJ reconstruction had some degree of transplanted bone resorption, and one patients had relapse of facial deformity. But the patients who had intraoral condylectomy via coronoid process resection only had mild condyle remodeling and no obvious bone resorption was noted.

CONCLUSIONSThe two methods of intraoral condylectomy introduced in this stugy can successfully correct the facial deformity and TMJ dysfunction caused by condylar osteoma or hyperplasia. But the surgeons need to have excellent surgical skills and careful selection of the indications.

Adult ; Facial Asymmetry ; surgery ; Female ; Follow-Up Studies ; Humans ; Hyperplasia ; Male ; Mandible ; diagnostic imaging ; pathology ; surgery ; Mandibular Condyle ; diagnostic imaging ; pathology ; surgery ; Mandibular Neoplasms ; diagnostic imaging ; pathology ; surgery ; Middle Aged ; Oral Surgical Procedures ; methods ; Osteoma ; diagnostic imaging ; pathology ; surgery ; Temporomandibular Joint ; physiology ; surgery ; Temporomandibular Joint Disorders ; surgery ; Tomography, X-Ray Computed ; Young Adult

Revascularization of immature necrotic teeth is a reliable treatment alternative to conventional apexogenesis or apexification. In case 1, a 12-year-old boy had his necrotic, immature mandibular left second premolar treated with a revascularization technique. At a24-month follow-up, periapical radiolucency had disappeared and thickening of the root wall was observed. In cases 2 and 3, a10-year-old boy had his necrotic, immature, bilateral mandibular second premolars treated with the same modality. At 48-month(in case 2) and 42-month (in case 3) follow-ups, loss of periapical radiolucencies and increases in the root wall thickness were also observed.
Apexification ; Bicuspid ; blood supply ; diagnostic imaging ; pathology ; surgery ; Child ; Dental Papilla ; blood supply ; drug effects ; pathology ; Dental Pulp ; blood supply ; drug effects ; pathology ; Dental Pulp Necrosis ; pathology ; therapy ; Follow-Up Studies ; Humans ; Male ; Mandible ; Neovascularization, Physiologic ; Radiography ; Regeneration ; Root Canal Irrigants ; therapeutic use ; Root Canal Therapy ; methods ; Tooth Apex ; blood supply ; diagnostic imaging ; Tooth, Deciduous ; blood supply ; pathology ; Treatment Outcome

OBJECTIVETo evaluate the clinical effect of mandibular osteomuscular flap pedicled with temporalis to repair maxillary defect.

METHODSFrom March 2008 to May 2010, ten cases of maxillary defects resulted from malignant tumor resection were treated with mandibular osteomuscular flap pedicled with temporalis. Ten cases of malignant tumor included six cases of Squamous cell carcinoma,one case of duct carcinoma, osteosarcoma, chondrosarcoma and malignant melanoma. One case was repaired by mandibular osteomuscular flap only, nine cases were repaired by mandibular osteomuscular flaps combined with other soft tissue flaps.

RESULTSAll the 10 mandibular osteomuscular flaps survived completely with no complication. The patients were followed up for 12 to 36 months, with an average of 18 months. Satisfactory appearance and complete functional restoration were achieved except for one case of chondrosarcoma recurrence.

CONCLUSIONSThe mandibular osteomuscular flap pedicled with temporalis is safe and easily performed with less complication. It is an ideal method for repairing the maxillary defect.

Aged ; Female ; Humans ; Male ; Mandible ; transplantation ; Maxilla ; pathology ; surgery ; Middle Aged ; Reconstructive Surgical Procedures ; methods ; Skin Transplantation ; Surgical Flaps ; Temporal Muscle ; transplantation ; Wound Healing

PURPOSE: The purpose of this study was to measure the anteroinferior changes and the degree of vertical changes to facilitate the prediction of treatment outcome in patients undergoing genioplasty only, genioplasty with bilateral sagittal split ramus osteotomy (BSSRO), genioplasty, or BSSRO and Lefort I osteotomy. MATERIALS AND METHODS: Serial cephalometry was performed on 25 patients at 1-year follow-up after genioplasty, to assess skeletal changes and relapse. Surgery was performed using conventional techniques. RESULTS: The mean ratio was 0.9 : 1 of soft tissue to skeletal movement at pogonion, but the average difference between hard and soft tissue was large; thus, the prediction of anteroposterior soft tissue changes was quite inaccurate. CONCLUSION: We observed a good correlation between the amount of hard versus soft tissue change with surgery in the horizontal direction, but a poor correlation in the vertical plane.
Adolescent ; Adult ; Female ; Humans ; Male ; Malocclusion, Angle Class III/pathology/*surgery ; Mandible/pathology/*surgery ; Osteotomy/methods ; Osteotomy, Le Fort/methods ; Reconstructive Surgical Procedures/*methods ; Treatment Outcome ; Young Adult

OBJECTIVETo repair segmental mandibular defects with autologous bone marrow stromal cells (BMSCs) engineered bone.

METHODSIsolated BMSCs were expanded in vitro and osteogenic induced. In 12 canines, a 3 cm segmental mandibular defect at right mandible was created. 6 canine's defects were repaired with cell-scaffold constructs made from induced BMSCs and coral; others were repaired with coral as control. The engineered bone was evaluated by X-ray, CT, Dual Energy X-ray Absorptiometry (DXA), gross and histological examination, and biomechanical test post-operatively.

RESULTSInduced BMSCs grew well on coral scaffold. At 12 weeks, X-ray showed more callus formed in experimental group, while evident scaffold duration in control group. At 32 weeks, gross observation, X-ray and CT demonstrated well bony-union in experimental group, while bony-nonunion in control group. Also DXA revealed significantly higher bone mineral density of experimental group than control group. Histologically, mature bone were commonly observed and there were bony healing in experimental group, while fibrous healing occurred in control group. Biomechanical test revealed no significant difference between experimental group and normal group.

CONCLUSIONSCanine segmental mandibular defects can be repaired with the tissue-engineered bone generated by coral scaffold with autologous osteogenic BMSCs.

Animals ; Anthozoa ; Bone Marrow Cells ; cytology ; Bone Substitutes ; Cell Culture Techniques ; Dogs ; Mandible ; pathology ; surgery ; Mesenchymal Stromal Cells ; cytology ; Pilot Projects ; Tissue Engineering ; Tissue Scaffolds ; Transplantation, Autologous

OBJECTIVETo investigate the indication, location and dose of postoperative radiotherapy for primary intraosseous carcinoma (PIOC) of the jaws.

METHODSFrom October 1969 to November 2005, 13 patients with PIOC were treated at the Cancer Hospital of Chinese Academy of Medical Sciences. Forty six cases with complete clinical data were collected from 27 published reports. Twenty-seven of the 59 patients were treated with surgery plus postoperative radiotherapy, and 22 with surgery alone.

RESULTSAll of the 13 cases in our series had advanced disease, and overall 1-, 2- and 3-year survival rats were 59.2%, 33.8% and 12.7% , respectively. For the reported 59 cases in literature, the overall 1-, 2- and 3-year survival rats were 78.4%, 53.9% and 34.0%, respectively. They were 84.3%, 57.2% and 43.6% for the patients treated by surgery plus postoperative radiotherapy, whereas they were 81.8%, 71.2% and 35.1% for the patients by surgery alone (P = 0.908). It seemed that surgery plus postoperative radiotherapy could not improve the survival of PIOC patients with involvement of adjacent soft-tissues or positive neck nodes or partial excision of primary tumor when compared with surgery alone, if the bias of selection in the patients for postoperative radiotherapy was neglected.

CONCLUSIONPostopreative radiotherapy may improve the survival for the patient with primary intraosseous carcinoma of the jaws. Our suggestion is that postoperative radiotherapy should be applied to the patient with any of the following items: positive operative margin; tumor involvement of adjacent soft-tissues; positive neck nodes; partial excision of primary tumor. However, the location and dose of postoperative radiotherapy may be varying at different situation.

Adult ; Aged ; Carcinoma, Squamous Cell ; pathology ; radiotherapy ; surgery ; Female ; Follow-Up Studies ; Humans ; Liver Neoplasms ; secondary ; Lymph Node Excision ; Lymphatic Metastasis ; Male ; Mandible ; surgery ; Mandibular Neoplasms ; pathology ; radiotherapy ; surgery ; Maxilla ; surgery ; Maxillary Neoplasms ; pathology ; radiotherapy ; surgery ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Radiotherapy, Adjuvant ; Radiotherapy, High-Energy ; Survival Rate ; Young Adult