AIM: To observe the morphology of corneal incision between femtosecond laser-assisted cataract surgery(FLACS)with 2.4mm micro-incision and conventional phacoemulsification cataract surgery(CPCS)with 2.4mm micro-incision, evaluating the safety and stability of the incision.

METHODS: This was a prospective controlled study. A total of 89 cataract patients(99 eyes)who underwent cataract surgery were collected. All patients were divided into two groups: 44 cases(49 eyes)in FLACS group and 45 cases(50 eyes)in CPCS group. Morphology of clear corneal incision was observed by OCTA postoperative.

RESULTS: There was no external wound dehiscence in FLACS group on 1d postoperative, while 10% patients had external wound dehiscence in CPCS group(P<0.05). There were no external wound dehiscence in both groups on 1wk, 1mo and 3mo postoperative. On 1wk and 1mo postoperative, the incidences of internal wound dehiscence in FLACS group(47% of 1wk and 10% of 1mo)were lower than that in CPCS group. There were statistically significant difference(68% of 1wk and 26% of 1mo)(P<0.05). On 1d and 3mo postoperative, there were no significant difference in internal wound dehiscence in both groups. There were no significant differences in descemet membrane detachment(DMD)in both groups.

CONCLUSION: Femtosecond laser-assisted cataract surgery(FLACS)is benefit for wound closure and reducing abnormal incision construction.

OBJECTIVETo evaluate the changes in retinal functions using multifocal electroretinography (mfERG) following intravitreal injection of Lucentis for treatment of wet age-related macular degeneration.

METHODSThis prospective study was conducted in 14 patients (9 men and 5 women, 14 eyes) with wet age-related macular degeneration receiving treatment with intravitreal injections of ranibizumab (Lucentis) in our hospital between October, 2014 and January, 2016. All the patients received the treatment following a 1+PRN protocol and after the initial injection, the patients were followed up monthly for 6 months to decide if additional injections were needed. The corrected visual acuity and mfERG findings of the patients were assessed before and at l, 3 and 6 months after the initial injection.

RESULTSAt the last follow-up, the patients received injections for a mean of 2.86∓1.58 times. The best corrected visual acuity (BCVA) at 1 month after the initial treatment was not significantly different from that before treatment (P=0.07), but showed significant improvements at 3 and 6 months (P<0.05). In mfERG, the implicit time of the 6 rings showed no significant decrease after the treatment, but the amplitude density of P1 and N1 in rings 1 and 2 improved significantly at 1, 3, and 6 months after the initial injection (P<0.05).

CONCLUSIONMultifocal electroretinography can serve as a useful modality for evaluating visual function changes in patients receiving intravitreal injection of Lucentis for wet age-related macular degeneration.