Introduction: Gestational diabetes mellitus (GDM) is a common pregnancy complication associated with adverse maternal and neonatal outcomes, including hypertensive disorders, caesarean delivery, macrosomia, and increased lifetime risk of type 2 diabetes. Despite its clinical importance, considerable international variation exists in GDM screening and diagnostic criteria. Multiple frameworks are currently used, including those from the World Health Organization (WHO), International Association of Diabetes and Pregnancy Study Groups, Carpenter and Coustan, and the National Diabetes Data Group. Differences in glucose thresholds, testing protocols (one-step versus two-step), and universal versus risk-based screening contribute to heterogeneity in reported prevalence and healthcare burden. In multi-ethnic, middle-income settings such as Malaysia, identifying an evidence-informed and contextappropriate diagnostic approach is critical. Methodology: This scoping review follows the Joanna Briggs Institute methodology and will be reported in accordance with the PRISMA Extension for Scoping Reviews (PRISMA-ScR). PubMed, Scopus, and ScienceDirect will be searched for English-language studies, reviews, guidelines, and consensus statements reporting GDM diagnostic criteria. Two reviewers will independently screen and select studies. Results: Data will be charted on country, study type, diagnostic criteria, gestational age at screening, and reported challenges. Findings will be synthesized descriptively and presented in tables and figures. No formal risk-of-bias assessment will be conducted. Conclusion This review will provide a comprehensive overview of global diagnostic practices, highlight variations and gaps, and support evidence-based selection of a suitable GDM screening and diagnostic strategy for Malaysia.
Diabetes, Gestational ; Malaysia ; Policy ; Review Literature as Topic

Introduction: Artificial intelligence (AI) and digital health technologies are increasingly integrated into diabetes care. However, data on awareness and adoption among endocrinologists in Malaysia remain limited. Methodology: A cross-sectional survey was conducted among endocrinologists in Malaysia using a structured online questionnaire. Items assessed awareness of AI-based diabetes technologies, attitudes toward AI in clinical care, perceived barriers, and willingness to adopt AI tools. Multiple responses were permitted for selected items. Results: The cohort (N = 65) comprised 60% junior endocrinologists and 40% senior endocrinologists (72% governmentbased). Recognition was higher for monitoring and screening technologies, particularly continuous glucose monitoring (CGM) data analytics (66.2%) and automated retinopathy screening (33.8%) versus therapeutic AI tools, such as lifestyle coaching applications (43.1%) and insulin titration algorithms (30.8%). While approximately 60% endocrinologists reported familiarity with AI in diabetes care, 15.4% of them had no prior recognition of AI tools. Attitudes toward AI were largely positive; 76% agreed that AI improves diabetes outcomes, 60% believed it reduces clinician workload, and 90% agreed that AI would complement diabetes care systems. However, approximately 50% remained neutral regarding its reliability and expressed concerns about ethics and data security. In practice, only 40% endocrinologists reported using AI tools, most commonly CGM analytics with automated insights (46.4%), with generally low frequency of use. The main barriers to adoption were lack of formal training (78.5%) and high implementation costs (60%). Despite this, 90% expressed willingness to adopt AI in future practice. Conclusion Awareness of AI technologies in diabetes care among Malaysian endocrinologists is variable, with stronger recognition of tools already embedded in routine practice. While attitudes toward AI are favorable, significant educational and structural barriers must be addressed to facilitate broader implementation.
Artificial Intelligence ; Endocrinologists ; Malaysia ; Diabetes Mellitus

INTRODUCTION: The profile of patients referred from primary to tertiary nephrology care is unclear. Ethnic Malay patients have the highest incidence and prevalence of kidney failure in Singapore. We hypothesised that there is a Malay predominance among patients referred to nephrology due to a higher burden of metabolic disease in this ethnic group. METHODS: This is a retrospective observational cohort study. From 2014 to 2018, a coordinator and physician triaged patients referred from primary care, and determined co-management and assignment to nephrology clinics. Key disease parameters were collated on triage and analysed. RESULTS: A total of 6,017 patients were studied. The mean age of patients was 64 ± 16 years. They comprised 57% men; 67% were Chinese and 22% were Malay. The proportion of Malay patients is higher than the proportion of Malays in the general population (13.4%) and they were more likely than other ethnicities to have ≥3 comorbidities, including diabetes mellitus, hypertension, hyperlipidaemia, coronary artery disease and stroke (70% vs. 57%, P < 0.001). Malay and Indian patients had poorer control of diabetes mellitus compared to other ethnicities (glycated haemoglobin 7.8% vs. 7.4%, P < 0.001). Higher proportion of Malay patients compared to other ethnicities had worse kidney function with estimated glomerular filtration rate (eGFR) <30 mL/min/1.73 m 2 on presentation (28% vs. 24%, P = 0.003). More ethnic Malay, Indian and younger patients missed appointments. CONCLUSION A disproportionately large number of Malay patients are referred for kidney disease. These patients have higher metabolic disease burden, tend to miss appointments and are referred at lower eGFR. Reasons underpinning these associations should be identified to facilitate efforts for targeting this at-risk population, ensuring kidney health for all.
Humans ; Male ; Female ; Retrospective Studies ; Middle Aged ; Singapore/epidemiology* ; Referral and Consultation/statistics & numerical data* ; Aged ; Nephrology ; Glomerular Filtration Rate ; Metabolic Diseases/epidemiology* ; Ethnicity ; Diabetes Mellitus/epidemiology* ; Malaysia/ethnology* ; Adult

Animals, Wild ; Borneo ; Malaysia ; Biosurveillance

Rare Diseases-Malaysia.

Introduction: There is an increasing number of publications on health literacy from Malaysia. We conducted a systematic review of Malaysian studies to determine the prevalence of limited general health literacy and the associated factors among Malaysian adults. Materials and Methods: We conducted a comprehensive search for Malaysian studies on health literacy using PubMed, Scopus and Google Scholar. Cross-sectional studies that measured general health literacy using specific rating scales among adults in Malaysia were retrieved for qualitative analysis. Quantitative synthesis of the prevalence of limited health literacy measured using two rating scales (Newest Vital Sign, NVS and various versions of European Health Literacy Survey, HLS) was performed using random effect model. Results: Twenty-five studies measuring general health literacy were retrieved for qualitative analysis; the majority were various versions of HLS and NVS. Pooled prevalence rates of limited health literacy were: HLS: 48.59%; NVS: 91.41%. Subgroup analysis of participant type revealed prevalence of limited health literacy measured using NVS was lower in clinical samples vs non-clinical samples (85.67% vs 94.70%). Moderator analysis revealed a small effect of ethnicity on prevalence of health literacy measured using HLS. Assessment of included studies showed very few of them had statistically significant associations between socio-demographic factors and limited health literacy. Conclusion Prevalence of limited health literacy in Malaysian adults was very high: almost one in two adults in HLS studies and nine out of ten adults in NVS studies. Socio-demographic factors associated with limited health literacy were inconsistent with other studies.
Adult ; Health Literacy ; Malaysia ; Prevalence ; Systematic Review [Publication Type]

Background: Pre-exposure prophylaxis (PrEP) is an evidence-based strategy recommended for at-risk populations for prevention of HIV transmission. However, the level of PrEP awareness and acceptance among Malaysian undergraduate students is currently unknown. Objectives: To assess the sexual activities, sexual behaviors, risk perception, awareness, and acceptance of PrEP of medical compared to non-medical students in a private medical university. Method: Demographic data, sexuality, sexual activity and behaviors, source of HIV knowledge, self- perceived risk of HIV, awareness and acceptance of PrEP were collected using an online anonymous survey among medical and non-medical students at a private medical university. Descriptive, comparative and regression analyses were performed where applicable. A p-value < 0.05 was considered statistically significant. Results: A total of 369 (187 medical, 182 non-medical) students responded. The median age was 22 with female:male ratio of 2:1. Eighty-one (22%) were sexually active of which 54% used condoms inconsistently, 58% had condomless sex in the preceding six months and 35% had casual or transactional sex. Despite this, 33 perceived themselves to be at low risk of HIV. Most learned about HIV from their coursework. PrEP awareness was 40% versus 20% while PrEP acceptance was 69% versus 67%, between medical and non-medical students, respectively. Conclusion Awareness of PrEP among medical students was low and even lower among non-medical students. PrEP acceptance was fair after viewing an introductory video on PrEP. PrEP must be included in the course curriculum. Studies to identify reasons for PrEP-hesitancy should be conducted to help guide policies and initiatives toward promoting PrEP as an additional tool in HIV prevention.
Malaysia ; HIV ; Awareness

Introduction: Cyberbullying is the use of information and communication technologies to support deliberate, repeated, and hostile behaviour by an individual or group to harm others. Cyberbullying may negatively affect the studies, personal lives and mental health of victims who are students. We report on the prevalence of cyberbullying and its effects on personal lives, studies, and mental health among medical students. Methods: A self-administered online questionnaire was used to collect demographic data, determine the prevalence of cyberbullying, and its effects on personal lives, studies and mental health of medical students. Student-t test was used for comparison of means, and logistic analysis was used to identify predictors of being cyberbullied. Results: 40 out of 261 study participants reported being cyberbullied in the preceding 6 months (prevalence: 15.3%). Cyberbullying did not negatively affect the studies and personal lives of victims. Most victims reported none or minimal-to-mild depression. Malay ethnicity was a predictor of being cyberbullied. Female students were 5-times more likely to be cyberbullied because of their lifestyle compared to males. Conclusion The prevalence of cyberbullying among medical students in this study was relatively low compared to reports from other universities. Cyberbullying had little to no effect on the studies, personal life, and mental health of medical students in our study. Malay ethnicity was a significant predictor to being cyberbullied. Females were more likely to be cyberbullied for their lifestyle. Support systems, awareness of good internet etiquette, and promotion of early help-seeking behaviour, especially targeted at identified vulnerable groups, should be put in place to check the practice of cyberbullying.
Malaysia ; Students, Medical ; Mental Health

Introduction: Lymphoma is a diverse group of malignant proliferations that arise as discrete tissue masses. The 5th edition of the World Health Organization classification of Tumours of Haematopoietic and Lymphoid Tissues was released on 22nd June 2022. The WHO-HAEM5 classification of Mature T and NK neoplasms is further subclassified into various categories which are detailed in this review. Methods: A search was conducted using bibliographic databases, various repositories, and the Clinical Research Centre website retrieving journal articles, conference proceedings, book Chapters, guidelines, and thesis. The search terms used were Malaysia AND lymphoma. Results: The search earmarked a total of 561 papers. There were nine case series retrieved from 1967 to 2022. The site, age distribution, prognostic markers, and the various subclassification of NK/T cell lymphomas were studied. The gastrointestinal tract was the commonest site for extranodal lymphomas. Prognostic markers associated were EBV, C-MYC protein and staining for CD2, CD3, CD20, CD56, and CD57 antigens. For anaplastic large cell lymphoma (ALCL), CD30 (Ki-1) and ALK antigens were noted as important. The use of 18F-Fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PETCT) has emerged as an important investigation. Various chemotherapeutic regimens, surgical interventions where necessary and autologous peripheral blood stem cell transplantation when indicated are the mainstay of treatment. Conclusion Research on NK/T cell lymphoma, including ALCL, has been ongoing in recent years. This review adds on to the existing literature on lymphoma in Malaysia that can lead to further research, into the diagnosis and treatment of lymphoma in Malaysia and around the world.
Lymphoma ; Lymphoma, Large-Cell, Anaplastic ; Malaysia

Introduction: The number of unvaccinated children and the rate of vaccination refusal among parents have recently increased despite the robust vaccination programme in Malaysia. The purpose of this study was to determine the level of knowledge of the Malaysian National Immunisation Programme among Malaysian parents as well as the variables that contribute to poor knowledge. Methods: This study used systematic random sampling to recruit 375 parents from seven health clinics in the Dungun District of Malaysia. The participants were asked to complete a self-administered validated questionnaire that included sociodemographic and knowledge questions. A multiple logistic regression analysis was applied to determine the associated factors of poor knowledge of immunisation. P-values of <0.05 were considered statistically significant. Results: A total of 189 (50.4%) respondents had poor knowledge of immunisation. The multiple logistic regression analyses revealed that a low educational level (adjusted odds ratio (OR): 1.92; 95% CI 1.25–2.95) was associated with poor knowledge while the age-group of 30-40 years old (adjusted OR: 0.56; 95% CI 0.34–0.93) was protected against it as compared to the age-group of <30 years old. Conclusion The prevalence of poor knowledge of immunisation among parents in Dungun, Terengganu, is relatively high. The focus of health promotion and education must be switched to increasing immunisation knowledge among the public, particularly among high-risk groups.
Knowledge ; Immunization ; Malaysia