1.Development and validation of a Filipino version of obstetric quality of recovery-10.
Rafael Jacob T. CARANDANG ; Ma. Carmela B. PABLO ; Guada Marie M. BONUS ; Ma. Patricia Mae J. QUINTIN ; Nan GUO ; Pervez SULTAN
Philippine Journal of Anesthesiology 2024;29(2):46-52
BACKGROUND
The Obstetric Quality of Recovery-10 (ObsQoR-10) is a patient-reported outcome measure that provides a holistic assessment on the quality of in-hospital postpartum functional recovery. Validated across several countries in various languages, it has shown great potential for widespread global acceptance in both clinical practice and research. We aimed to develop a Filipino version of the ObsQoR-10 and to evaluate its validity, reliability, and feasibility.
METHODSOne hundred women who had elective cesarean delivery (CD) completed the ObsQoR-10-Filipino and EuroQol five-dimensional 3 L Filipino version questionnaires (including a Global Health Visual Analog Scale [GHVAS]) 24 h after delivery. Twenty-five women completed the ObsQoR-10-Filipino survey again 25 h after delivery. Validity was assessed by evaluation of convergent validity, discriminant validity, and hypothesis testing. Reliability was assessed by evaluating internal consistency, split-half reliability, and test–retest reliability; and (iv) floor and ceiling effects.
RESULTSThe ObsQoR-10-Filipino scores showed good and moderate correlation to the EQ-5D-3 L scores (r = −0.636; 95% confidence interval [CI]: −0.740–−0.503, P < 0.001) and to the GHVAS scores (r = 0.387; 95% CI: 0.207–0.543, P < 0.001), respectively. ObsQoR-10-Filipino discriminated well between good (GHVAS score ≥ 70, 68.4 ± 12.9) and poor recovery (GHVAS score < 70, 55.1 + 12.9). Internal consistency was acceptable (Cronbach’s α =0.76), and split-half reliability was very good (Spearman–Brown Prophesy Reliability Estimate = 0.87). Test–retest reliability was excellent (intraclass correlation coefficient = 0.973; 95% CI: 0.873–0.976). No floor or ceiling effects were observed. The recruitment rate and completion rate were 92% and 91%, respectively. No correlation was observed between the ObsQoR-10-Filipino scores and factors such as maternal age, gestational age, blood loss, and American Society of Anesthesiologists classification.
CONCLUSIONThe ObsQoR-10-Filipino is a valid, reliable, and feasible tool for assessing inatient postpartum recovery in Filipino-speaking women undergoing elective CD.
Human ; Cesarean Section ; Anesthesia, Obstetrical
2.Development and validation of a Filipino version of obstetric quality of recovery-10.
Rafael Jacob T. CARANDANG ; Ma. Carmela B. PABLO ; Guada Marie M. BONUS ; Ma. Patricia Mae J. QUINTIN ; Nan GUO ; Pervez SULTAN
Philippine Journal of Anesthesiology 2024;29(2):46-52
BACKGROUND
The Obstetric Quality of Recovery-10 (ObsQoR-10) is a patient-reported outcome measure that provides a holistic assessment on the quality of in-hospital postpartum functional recovery. Validated across several countries in various languages, it has shown great potential for widespread global acceptance in both clinical practice and research. We aimed to develop a Filipino version of the ObsQoR-10 and to evaluate its validity, reliability, and feasibility.
METHODSOne hundred women who had elective cesarean delivery (CD) completed the ObsQoR-10-Filipino and EuroQol five-dimensional 3 L Filipino version questionnaires (including a Global Health Visual Analog Scale [GHVAS]) 24 h after delivery. Twenty-five women completed the ObsQoR-10-Filipino survey again 25 h after delivery. Validity was assessed by evaluation of convergent validity, discriminant validity, and hypothesis testing. Reliability was assessed by evaluating internal consistency, split-half reliability, and test–retest reliability; and (iv) floor and ceiling effects.
RESULTSThe ObsQoR-10-Filipino scores showed good and moderate correlation to the EQ-5D-3 L scores (r = −0.636; 95% confidence interval [CI]: −0.740–−0.503, P < 0.001) and to the GHVAS scores (r = 0.387; 95% CI: 0.207–0.543, P < 0.001), respectively. ObsQoR-10-Filipino discriminated well between good (GHVAS score ≥ 70, 68.4 ± 12.9) and poor recovery (GHVAS score < 70, 55.1 + 12.9). Internal consistency was acceptable (Cronbach’s α =0.76), and split-half reliability was very good (Spearman–Brown Prophesy Reliability Estimate = 0.87). Test–retest reliability was excellent (intraclass correlation coefficient = 0.973; 95% CI: 0.873–0.976). No floor or ceiling effects were observed. The recruitment rate and completion rate were 92% and 91%, respectively. No correlation was observed between the ObsQoR-10-Filipino scores and factors such as maternal age, gestational age, blood loss, and American Society of Anesthesiologists classification.
CONCLUSIONThe ObsQoR-10-Filipino is a valid, reliable, and feasible tool for assessing inatient postpartum recovery in Filipino-speaking women undergoing elective CD.
Human ; Cesarean Section ; Anesthesia, Obstetrical
3.A meta-analysis on the comparison of carbetocin versus oxytocin on additional uterotonic use, incidence of postpartum hemorrhage, and need for blood transfusion after cesarean section under neuraxial anesthesia.
Guada Marie M. BONUS ; Ma. Patricia Mae J. QUINTIN ; Rafael Jacob T. CARANDANG
Philippine Journal of Anesthesiology 2024;29(1):13-22
Postpartum hemorrhage (PPH) remains to be the leading cause of maternal deaths worldwide. The first-line treatment in its prevention is the administration of uterotonics before the delivery of the placenta. Recently, a newer synthetic analog has been developed – carbetocin. With its introduction, new questions arise as to which is more effective in preventing PPH. Four major electronic databases were searched for randomized controlled trials comparing carbetocin and oxytocin in terms of additional uterotonic use, incidence of PPH, and need for blood transfusion. Only randomized controlled studies involving pregnant women undergoing cesarean section under regional anesthesia were included. Outcomes included are the need for additional uterotonic use, the incidence of PPH, and the need for blood transfusion. Of the three outcomes, carbetocin was found to show statistically significant protection against the need for additional uterotonic administration and the need for blood transfusion. Results showed that carbetocin provided a statistically significant risk reduction for the need for additional uterotonics (risk ratio [RR] = 0.53, 95% confidence interval [CI] 0.46–0.81,P< 0.00001) and need for blood transfusion (RR = 0.34, 95% CI 0.19–0.62,P= 0.0004). Need for additional uterotonics and for blood transfusion was found to be almost twice (1/0.53 = 1.88) and almost thrice (1/0.34 = 2.94) as likely, respectively, to occur in the oxytocin group versus the carbetocin group. Reduction of PPH pointed toward carbetocin providing greater protection against it, but it was found not to be statistically significant (RR = 0.85, 95% CI 0.56–1.28,P= 0.43).
Cesarean Section ; Oxytocin ; Blood Transfusion ; Postpartum Hemorrhage ; Carbetocin


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