INTRODUCTION: Actinomycetoma is a neglected infectious disease that presents with a triad of subcutaneous mass, with sinus formation and seropurulent discharge containing grains. This causes severe functional disability to patients if not treated early and properly. CASE REPORT: We report a case of a 62-year-old adult Filipino farmer diagnosed with actinomycetoma of the left foot. For 8 years, the patient medicated with several antibiotic therapies affording minimal improvement of symptoms. Hence, surgical intervention with combination antimicrobial therapy was done which provided resolution of symptoms, improving the quality of life of the patient. CONCLUSION Treatment of actinomycetoma must be individualized among patients. Although oral antibiotics became the standard of treatment, combining surgical treatment with oral medications may be considered to ensure effective management of the disease.
actinomycetoma ; cotrimoxazole ; dapsone ; surgery ; case report

Introduction: Basal cell carcinoma (BCC) is the most common type of malignancy worldwide. The incidence of BCC is positively associated with increasing age; thus, centenarians, defined as those aged 100 years and above, become a vulnerable population to developing malignancy. As a person ages, risk factors such as chronic sun exposure, ionizing radiation, and immunosuppres- sion induce mutations that contribute to tumor formation. Impaired DNA repair capacity in response to carcinogens and immune function dysfunction also increases BCC risk in the elderly. Currently, studies among centenarians with high-risk basal cell car- cinoma treated with surgical interventions are limited. Case report: Presented herewith is a case of a 101-year-old female with a 15-year history of hyperpigmented, hyperkeratotic plaque over the right malar area and a one-year history of progressive pain (PS 10/10) and enlargement of the lesion, forming an ulcerated, hyperpigmented tumor. Laboratory workup showed normal findings. Histopathology was signed out as a pigmented nodulocystic basal cell carcinoma. Moh’s micrographic surgery (MMS) and cheek advancement flap were performed with good wound healing and no perioperative complications. Conclusion Despite the limited options of medical and physical management due to decreased life expectancy of centenar- ians, MMS remains the standard of therapy in high-risk BCC. MMS with reconstructive surgery is generally a safe and effective modality with no increased risk of peri- and post-operative complications.
Carcinoma, Basal Cell ; Centenarians

Primary systematic amyloidosis is a rare disorder characterized by multi system amyloid deposition occasionally associated with multiple myeloma and poor prognosis. We report 64-year-old male who presented with bilateral erythematous to hyperpigmented , waxy, soft, non-tender plaques on the upper eyelids and some hematomas over the face, trunk and arms with no other associated manifestations. Skin biopsy of the eyelid revealed amyloid deposits and serum protein electrophoresis showed multiple myeloma. After a series of tests, the patient was diagnosed to have systemic amyloidosis with multiple myeloma. Patient was treated with melphalan and prednisone combination therapy. Improvement of cutaneous lesions was noted after the first cycle of chemotherapy characterized as decrease in size of the eye lesions. To the best of our knowledge, this is the first case of amyloidosis with multiple myeloma to be published in the Philippines.

Human ; Male ; Middle Aged ; Amyloidosis ; Biopsy ; Blood Proteins ; Electrophoresis ; Eyelids ; Hematoma ; Melphalan ; Multiple Myeloma ; Philippines ; Plaque, Amyloid ; Prednisone ; Prognosis ; Skin Diseases ; Waxes

A 40-year-old male presented with multiple erythematous scaly plaques over the right cheek, lips, left preauricular area, 'v' neck areas, the upper extremities, and a large fungating flesh colored tumor on the nasal bridge extending to right eyelid and malar area. Histologically, the plaque lesions were consistent with discoid lupus erythematosus (DLE), and the fungating growth with squamous cell carcinoma (SCC).

Human ; Male ; Adult ; Carcinoma, Squamous Cell ; Cheek ; Lip ; Lupus Erythematosus, Discoid ; Neck ; Skin