The B-cell scaffold protein with ankyrin repeats 1(BANK1)is a B-cell scaffold protein 1 containing ankyrin repeats,which has been found to be associated with genetic variants in various autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.Changes in the expression of the BANK1 gene in B cells are thought to be a key factor in genetic variants in autoimmune diseases.This article reviews the basic characteristics of BANK1 and its association with autoimmune diseases,aiming to provide innovative perspectives and research directions for the scientific research of autoimmune diseases.

The B-cell scaffold protein with ankyrin repeats 1(BANK1)is a B-cell scaffold protein 1 containing ankyrin repeats,which has been found to be associated with genetic variants in various autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis.Changes in the expression of the BANK1 gene in B cells are thought to be a key factor in genetic variants in autoimmune diseases.This article reviews the basic characteristics of BANK1 and its association with autoimmune diseases,aiming to provide innovative perspectives and research directions for the scientific research of autoimmune diseases.