1.Application of transcranial magnetic stimulation in rehabilitation field:a bibliometric analysis from 2014 to 2024
Haifang LAI ; Benhui LIU ; Lijun CUI ; Longang HUA ; Qing XIE
Chinese Journal of Rehabilitation Theory and Practice 2025;31(5):581-591
Objective To analyze the research hotspots and frontier trends of transcranial magnetic stimulation(TMS)in the field of rehabilitation in the last decade.Methods The literatures of TMS in the field of rehabilitation from January,2014 to September,2024 were searched in the database of Web of Science core collection,and the visual analysis was carried out by using CiteSpace 6.4.R1 software.Results A total of 1 065 articles were included,showing an increasing trend in annual publication volume.China was the leading country in publication volume,Harvard University was the institution with the largest number of pub-lished articles,and Simone Rossi was the most frequently cited author.Keywords with high co-occurrence fre-quency included stroke,noninvasive brain stimulation,plasticity,cortical excitability,θ burst stimulation and up-per limb.Brain-computer interface was the bursting keyword in the past two years.Conclusion In the past decade,the research interest in TMS in the field of rehabilitation has been on the rise.It focused on the application of multimodal combined therapies,including TMS,to improve the upper limb function and aphasia of stroke patients and to explore the plasticity of brain nerves.Future research should focus on the deep integration of TMS and brain-computer interface technology to realize the individualization and accuracy of TMS treatment.
2.Effect of transcutaneous auricular vagus nerve stimulation on patients with prolonged disorders of consciousness
Longang HUA ; Haifang LAI ; Wei YANG ; Yong LIU ; Xiangming YE
Chinese Journal of Rehabilitation Theory and Practice 2025;31(3):339-347
Objective To investigate the effect of transcutaneous auricular vagus nerve stimulation(ta-VNS)on the recovery of con-sciousness in patients with prolonged disorders of consciousness(pDoC).Methods From January,2023 to August,2024,50 patients with pDoC in Zhejiang Provincial People's Hospital were ran-domly divided into control group(n=25)and observation group(n=25).Both groups received conventional wakefulness-promoting treatment and Xingnao Kaiqiao acupuncture,and the observation group added ta-VNS treatment on the basis of the control group,for four weeks.Each group was further divided into unresponsive wakefulness syndrome/vegetative state(UWS/VS)and minimally consciousness state(MCS)types based on their initial the score of Coma Recovery Scale-Revised(CRS-R).They were assessed with Glasgow Coma Scale(GCS),CRS-R,EEG grading and upper limb somatosensory-evoked potentials(SSEP)before and four weeks af-ter treatment.Results Three in the observation group and five in the control group dropped down for transferring to other hospitals.There was no significant difference in all the indexes between two groups before treatment(P>0.05).After treat-ment,the GCS score(|t|>16.000,P<0.001),CRS-R score(|t|>14.318,P<0.001)and N20 amplitude of SSEP(|t|>5.247,P<0.05)improved,the EEG grading was reduced(Z>2.264,P<0.05),and the N20 latency of SSEP was shortened(|t|>2.884,P<0.05)in both UWS/VS and MCS type patients in the observation group;and they were better in the observation group than in the control group for the same type(|t|>1.883,|Z|>2.244,P<0.05).Conclusion ta-VNS can significantly promote the awakening of patients with pDoC from UWS/VS and MCS,and im-prove the functional status of electroencephalogram activities and sensorimotor conduction pathways.
3.Effect of transcutaneous auricular vagus nerve stimulation on patients with prolonged disorders of consciousness
Longang HUA ; Haifang LAI ; Wei YANG ; Yong LIU ; Xiangming YE
Chinese Journal of Rehabilitation Theory and Practice 2025;31(3):339-347
Objective To investigate the effect of transcutaneous auricular vagus nerve stimulation(ta-VNS)on the recovery of con-sciousness in patients with prolonged disorders of consciousness(pDoC).Methods From January,2023 to August,2024,50 patients with pDoC in Zhejiang Provincial People's Hospital were ran-domly divided into control group(n=25)and observation group(n=25).Both groups received conventional wakefulness-promoting treatment and Xingnao Kaiqiao acupuncture,and the observation group added ta-VNS treatment on the basis of the control group,for four weeks.Each group was further divided into unresponsive wakefulness syndrome/vegetative state(UWS/VS)and minimally consciousness state(MCS)types based on their initial the score of Coma Recovery Scale-Revised(CRS-R).They were assessed with Glasgow Coma Scale(GCS),CRS-R,EEG grading and upper limb somatosensory-evoked potentials(SSEP)before and four weeks af-ter treatment.Results Three in the observation group and five in the control group dropped down for transferring to other hospitals.There was no significant difference in all the indexes between two groups before treatment(P>0.05).After treat-ment,the GCS score(|t|>16.000,P<0.001),CRS-R score(|t|>14.318,P<0.001)and N20 amplitude of SSEP(|t|>5.247,P<0.05)improved,the EEG grading was reduced(Z>2.264,P<0.05),and the N20 latency of SSEP was shortened(|t|>2.884,P<0.05)in both UWS/VS and MCS type patients in the observation group;and they were better in the observation group than in the control group for the same type(|t|>1.883,|Z|>2.244,P<0.05).Conclusion ta-VNS can significantly promote the awakening of patients with pDoC from UWS/VS and MCS,and im-prove the functional status of electroencephalogram activities and sensorimotor conduction pathways.
4.Application of transcranial magnetic stimulation in rehabilitation field:a bibliometric analysis from 2014 to 2024
Haifang LAI ; Benhui LIU ; Lijun CUI ; Longang HUA ; Qing XIE
Chinese Journal of Rehabilitation Theory and Practice 2025;31(5):581-591
Objective To analyze the research hotspots and frontier trends of transcranial magnetic stimulation(TMS)in the field of rehabilitation in the last decade.Methods The literatures of TMS in the field of rehabilitation from January,2014 to September,2024 were searched in the database of Web of Science core collection,and the visual analysis was carried out by using CiteSpace 6.4.R1 software.Results A total of 1 065 articles were included,showing an increasing trend in annual publication volume.China was the leading country in publication volume,Harvard University was the institution with the largest number of pub-lished articles,and Simone Rossi was the most frequently cited author.Keywords with high co-occurrence fre-quency included stroke,noninvasive brain stimulation,plasticity,cortical excitability,θ burst stimulation and up-per limb.Brain-computer interface was the bursting keyword in the past two years.Conclusion In the past decade,the research interest in TMS in the field of rehabilitation has been on the rise.It focused on the application of multimodal combined therapies,including TMS,to improve the upper limb function and aphasia of stroke patients and to explore the plasticity of brain nerves.Future research should focus on the deep integration of TMS and brain-computer interface technology to realize the individualization and accuracy of TMS treatment.

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