In recent years,increasingly diverse methods have been employed to prevent and treat radiation enteritis(RE).Improvements in radiotherapy techniques,optimization of radiation dose fractionation,and development and use of radioprotective agents have reduced the incidence of RE,and new treatment modalities,including hormones,mucosal protectants,endoscopic treatments,and surgical interventions,together with emerging therapies,including microbiome-based treatments,stem cell transplantation,and hyperbaric oxygen therapy,have made significant progress.These new technologies and treatments exhibit potential efficacy at alleviating symptoms,protecting the intestin-al barrier,promoting tissue repair,and restoring intestinal microbiota balance.Here,we review the latest research investigating treatment and prevention of RE,exploring the optimization of radiation therapy techniques,and developing strategies for prevention and treatment,with the aim of providing a theoretical basis for more precise,comprehensive,and effective treatment options for RE.

In recent years,increasingly diverse methods have been employed to prevent and treat radiation enteritis(RE).Improvements in radiotherapy techniques,optimization of radiation dose fractionation,and development and use of radioprotective agents have reduced the incidence of RE,and new treatment modalities,including hormones,mucosal protectants,endoscopic treatments,and surgical interventions,together with emerging therapies,including microbiome-based treatments,stem cell transplantation,and hyperbaric oxygen therapy,have made significant progress.These new technologies and treatments exhibit potential efficacy at alleviating symptoms,protecting the intestin-al barrier,promoting tissue repair,and restoring intestinal microbiota balance.Here,we review the latest research investigating treatment and prevention of RE,exploring the optimization of radiation therapy techniques,and developing strategies for prevention and treatment,with the aim of providing a theoretical basis for more precise,comprehensive,and effective treatment options for RE.

In recent years,significant progress has been made in screening for and diagnosis of colorectal cancer(CRC),particularly using fecal nucleic acid detection.In addition to fecal occult blood tests,fecal screening technologies including fecal nucleic acid testing,multi-tar-get DNA testing,and protein biomarker detection,have become research hotspots.Numerous studies at home and abroad have identified various fecal nucleic acids and biomarkers with potential value for screening and early diagnosis of CRC.Fecal nucleic acid and biomarker testing can accurately detect early stage cancer and precancerous lesions,thereby improving early detection rates and reducing CRC incid-ence and mortality.This article reviews research progress into fecal nucleic acid testing in CRC screening,discusses the application prospects of biomarkers and optimization of detection techniques,and provides a basis for the development of more accurate and efficient screening methods.