1.Correlation Between Fractional Area Change of Left Ventricle Measured by Cardiac Magnetic Resonance and Myocardial Circumferential Strain
Menglu LI ; Heng ZHANG ; Chunjie WANG ; Fuzhuang JIANG ; Kaizhou YANG ; Yuanyuan XING ; Fangmin PEI ; Liuquan CHENG
Chinese Journal of Medical Imaging 2025;33(7):739-744
Purpose To compare the similarity between the short-axis left ventricular cavity fractional area change measured by cardiac magnetic resonance and myocardial circumferential strain.Materials and Methods Forty cases of cardiomyopathy with different phenotypes and high-quality cardiac magnetic resonance images in PACS data center of the Sixth Medical Center of Chinese PLA General Hospital were retrospectively selected.All patients underwent cine imaging on a 3.0T MRI scanner.The endocardial and epicardial areas of each short-axis left ventricular slice were measured using Medviso Segment software to calculate slice-level fractional area change and global fractional area change.Slice circumferential strain and global circumferential strain were measured using Circle CVI42 software.Linear regression analysis was performed to assess correlations between global circumferential strain and global fractional area change,as well as slice circumferential strain and slice-level fractional area change.Results Both global circumferential strain and global fractional area change,as well as slice circumferential strain and slice-level fractional area change,exhibited positive correlations(all r>0.95).Linear regression demonstrated significant relationships(regression coefficients:2.40-3.16,P<0.05),with coefficient magnitudes related to left ventricular cavity radius.After normalization,circumferential strain and fractional area change curves showed identical standard deviations.Conclusion Short-axis left ventricular cavity fractional area change and myocardial circumferential strain display significant positive correlations at both slice and global levels,with similar curve morphology.These findings suggest that circumferential strain and fractional area change possess comparable statistical value in assessing cardiac function.
2.Interpretation of 2025 ESC Guidelines for the Management of Pericarditis and Myocarditis—Emphasizing the Diagnostic and Therapeutic Application of Noninvasive Imaging
Chinese Journal of Medical Imaging 2025;33(10):1030-1034
The incidence of myocarditis and pericarditis has been steadily increasing.Over the past decade,significant advances in pathophysiology,diagnostic techniques and prognostic assessment have led to the continuous refinement of effective management strategies.In 2025,the European Society of Cardiology(ESC)released new guidelines for the management of myocarditis and pericarditis to guide clinical practice.The guidelines introduced the overarching concept of inflammatory myopericardial syndrome(IMPS).This article provides an interpretation of the diagnosis and management of IMPS from the perspective of noninvasive cardiovascular imaging,highlighting the pivotal role of imaging in the new ESC framework.
3.Interpretation of 2025 ESC Guidelines for the Management of Pericarditis and Myocarditis—Emphasizing the Diagnostic and Therapeutic Application of Noninvasive Imaging
Chinese Journal of Medical Imaging 2025;33(10):1030-1034
The incidence of myocarditis and pericarditis has been steadily increasing.Over the past decade,significant advances in pathophysiology,diagnostic techniques and prognostic assessment have led to the continuous refinement of effective management strategies.In 2025,the European Society of Cardiology(ESC)released new guidelines for the management of myocarditis and pericarditis to guide clinical practice.The guidelines introduced the overarching concept of inflammatory myopericardial syndrome(IMPS).This article provides an interpretation of the diagnosis and management of IMPS from the perspective of noninvasive cardiovascular imaging,highlighting the pivotal role of imaging in the new ESC framework.
4.Correlation Between Fractional Area Change of Left Ventricle Measured by Cardiac Magnetic Resonance and Myocardial Circumferential Strain
Menglu LI ; Heng ZHANG ; Chunjie WANG ; Fuzhuang JIANG ; Kaizhou YANG ; Yuanyuan XING ; Fangmin PEI ; Liuquan CHENG
Chinese Journal of Medical Imaging 2025;33(7):739-744
Purpose To compare the similarity between the short-axis left ventricular cavity fractional area change measured by cardiac magnetic resonance and myocardial circumferential strain.Materials and Methods Forty cases of cardiomyopathy with different phenotypes and high-quality cardiac magnetic resonance images in PACS data center of the Sixth Medical Center of Chinese PLA General Hospital were retrospectively selected.All patients underwent cine imaging on a 3.0T MRI scanner.The endocardial and epicardial areas of each short-axis left ventricular slice were measured using Medviso Segment software to calculate slice-level fractional area change and global fractional area change.Slice circumferential strain and global circumferential strain were measured using Circle CVI42 software.Linear regression analysis was performed to assess correlations between global circumferential strain and global fractional area change,as well as slice circumferential strain and slice-level fractional area change.Results Both global circumferential strain and global fractional area change,as well as slice circumferential strain and slice-level fractional area change,exhibited positive correlations(all r>0.95).Linear regression demonstrated significant relationships(regression coefficients:2.40-3.16,P<0.05),with coefficient magnitudes related to left ventricular cavity radius.After normalization,circumferential strain and fractional area change curves showed identical standard deviations.Conclusion Short-axis left ventricular cavity fractional area change and myocardial circumferential strain display significant positive correlations at both slice and global levels,with similar curve morphology.These findings suggest that circumferential strain and fractional area change possess comparable statistical value in assessing cardiac function.
5.A retrospective comparison of MRI, ultrasound and X-ray mammography in detecting breast ductal carcinoma in situ
Yuxin LI ; Yingxuan WANG ; Liuquan CHENG ; Yiqiong ZHENG ; Mei LIU ; Zhili WANG ; Xiru LI ; Jiandong WANG ; Menglu LI
Chinese Journal of Radiology 2020;54(6):557-562
Objective:To compare the efficacies of MRI, X-ray mammography (XMG) and Ultrasound (US) in detecting and diagnosing breast ductal carcinoma in situ (DCIS).Methods:Two hundred and forty one consecutive patients with pathology-confirmed DCIS were retrospectively recruited from January 2011 to December 2017 in PLA General Hospital. The imaging examination modalities included MRI and/or XMG and/or US.The breast imaging reporting and data system (BI-RADS) categorizations by MRI, XMG and US were compared and their sensitivities of detecting DCIS were calculated. The causes of underestimation on MRI were interpreted with the information of XMG and US. Chi-square test was used to compare the differences.Results:The diagnostic sensitivity of XMG, US and MRI was 65.9% (29/44), 71.6% (101/141) and 91.2% (145/159), respectively, with statistical significant differences (χ2 =24.034, P<0.001). Breast density and lesion type would influence the sensitivity of XMG. And the sensitivity of US was decreased because of non-mass lesion. Of the 14 cases under-evaluated as BI-RADS category 1 to 3 on MRI, 5 were corrected by XMG and/or US to BI-RADS category 4. The cause of underestimation on MRI was the coexistence of DCIS with adenoma or other benign lesion. Conclusion:The retrospective comparison of MRI, XMG and US in this study showed that MRI had significant higher sensitivity in detecting breast DCIS, while the false negative rates of XMG and US were un-negligible.
6.MRI measurement of left ventricle myocardial strain on short axis in normal youth
Menglu LI ; Junchao LI ; Liuquan CHENG ; Yundai CHEN ; Wei DONG ; Guang ZHI ; Xiaoxu XI ; Xiaojing ZHANG
Chinese Journal of Radiology 2018;52(12):913-918
Objective To learn the endocardial strain patterns of the left ventricles on the short-axis views in normal youth volunteers using feature tracking techniques on cine cardiac MR imaging,and to build up the reference ranges of strain peak and time to peak (TTP) for endocardial strain analysis.Methods Twenty-nine normal youth volunteers aged from 24-34 years old were enrolled in the study in march 2015.The Cine MR imaging were acquired using balance FFE sequence with 24 phases for each cardiac cycle.The standard short-axis imaging planes were basal,mid-cavity and apical levels and divided into 16 segments.The peaks and TTPs of myocardial displacement and its velocity,radial and circumferential strain and strain rate and its velocity in each segment were calculated using feature tracking techniques.The data with normal distribution were analyzed by ANOVA and Student-Newman-Keuls (SNK) method,and Kruskal-Wallis and Wilcoxon rank sum test were used for the data without normal distribution.Results The peaks and TTPs of radial strain and strain rate differed in 16-segmental levels and basal,middle and apical plane levels and had no concordant reference ranges.The circumferential strain and strain rate were homogeneous at basal and middle plane levels [(-27.09 ±9.51)%,(1.94 ±0.98)/s,respectively].Their TTPs were homogenous [0.38 (0.08)RR,0.54 (0.08)RR,respectively],and there were no significant differences in planar-segments or inter-segment level.Except for middle level,the peaks of radial displacement and velocity differed in basal and apical levels and had no concordant reference ranges.But radial velocity TTPs were homogeneous in all 16 segments [0.21 (0.04)RR].Except for the radial strain rate,TTPs showed no significant difference between basal level and middle level.The measurements at apical level revealed high variance.No regular pattern could be found on individual peak and TTP curves of velocity and strain rate.Conclusion The peaks and TTPs of radial strain are different in segmental and planar levels without a concordant reference range.The peaks and TFPs of circumferential strain and the radial velocity rTTPs are homogeneous in middle and apical plane level and have homogeneous reference range.
7.MRI Study of Strain Feature of Left Ventricular Long-axis Myocardium in Normal Young Adults
Menglu LI ; Xiaoxu XI ; Liuquan CHENG ; Junchao LI ; Wei DONG ; Yundai CHEN ; Guang ZHI
Chinese Journal of Medical Imaging 2018;26(4):258-263
Purpose To measure the longitudinal and transverse strain and displacement parameters of each segment of long axis myocardium on cardiac MRI film images of normal young volunteers using feature tracking technique (FT), and to analyze the regularity of left ventricular long axis strain and establish peak and time to peak (TTP) reference range concerning the longitudinal and transverse strain and displacement. Materials and Methods Cardiac film images of 29 healthy volunteers aged 24 to 34 were collected using Philips Multiva 1.5T MRI scanner, including three typical long axis planes of the left ventricular long axis, left ventricular outflow tract, and four-chamber view. The MRI film images were analyzed drawing on myocardial feature tracking software TOMTEC, and the peak value and TTP of longitudinal and transverse strain and displacement of the 16 AHA segments excluding apex cordis were obtained thereby. The regularity of each parameter concerning the plane, layer, and segment was summarized and analyzed. Results The TTP of longitudinal strain, longitudinal displacement and transverse strain were consistent among each myocardial segment, which was a constant indicator in (41.24±12.51) % RR interphase. The peak value of longitudinal displacement was represented by apex cordis (2.56±0.89) mm < middle (6.09±2.03) mm < cardiac base (8.07±2.05) mm, and the peak value of transverse displacement was manifested as apex cordis (4.57±1.18) mm < middle (5.65±0.84) mm < cardiac base (8.48 ±1.18) mm, which was consistent with cardiac geometric deformation visually observed. The longitudinal strain showed consistency on 2CH-3CH-4CH plane, whose peak reference value was (-22.46±13.19)%; while the peak value of transverse strain displayed no consistency on different planes. Conclusion The longitudinal strain of the left ventricular on different planes has consistent peak value and TTP, suggesting good reference value.
8.Radiologist-technologist integration training program: Evaluation and practice
Journal of Medical Postgraduates 2017;30(5):449-452
The radiologist-technologist integration (RTI)training program involves radiologists′ participation in technologists′ scan and examination training and technologists′ participation in physicians′preparation of reports during their residency training.Based on the investigations in the PLA General Hospital, West China Hospital of Sichuan University, The SecondXiangyaHospitalofCentralSouthUniversity, International Hospital of Peking University, and The First Hospital of Qinhuangdao, the author evaluated the methods of and practice in RTItraining as well as the potential value of RTI and itsfacilitation of work quality.RTItraining has effectively enhanced the basic skills training of the residents, deepened their understanding of the imaging process, and promoted scientific research and clinical work.The RTI training program can cultivate the technologists′ abilities to identify lesions, design individual protocols, and achieve the targeted scan for diagnosis.Meanwhile, itmay contribute to the improvement of human resource management inthe radiology department and overall quality of radiological examinations.
9.A comparison of echocardiography with magnetic resonance imaging in measurement of cardiac function in patients with dilated cardiomyopathy
Songtao HUANG ; Jiaying ZHAO ; Lanxiang LIU ; Zhanqiu WANG ; Liuquan CHENG
Chinese Journal of Endemiology 2016;35(8):616-619
Objective To compare the difference of echocardiography and magnetic resonance imaging (MRI) in measurement of cardiac function in patients with dilated cardiomyopathy (DCM).Methods Totally 41 patients with DCM underwent echocardiography and MRI to measure cardiac function,the parameters included left ventricular end-diastolic volume (LVEDV),end systolic volume (LVESV),left ventricular ejection fraction (LVEF) and stroke volume (SV).The vertical long axis (VLA),horizontal long axis (HLA) and short axis (SA) of heart were measured by echocardiography.The differences of echocardiography and MRI were compared by linear regression and linear correlation.Results ①The value of LVEDV and LVESV obtained by the two methods:the value of LVEDV [(262.6 ± 117.0) ml] and LVESV [(196.4 ± 109.8) ml] obtained by MRI were higher than those of echocardiography [(211.4 ± 90.6),(216.5 ± 71.5),(219.1 ± 80.1) ml;(153.3 ± 76.1),(153.9 ± 54.1),(157.0 ± 61.1) ml,all P < 0.05].②The value of SV and LVEF obtained by the two methods:the value of SV[(66.2 ± 21.3) ml] obtained by MRI was higher than that of echocardiography VLA [(58.1 ± 14.4) ml,P < 0.05].The value of LVEF [(25.2 ±7.2)%] obtained by MRI was lower than those of echocardiography HLA and echocardiography SA [(28.9 ± 6.1)%,(28.3 ± 6.1)%,all P < 0.05].③The value of LVEDV and LVESV obtained by echocardiography SA were associated with those obtained by MRI (r =0.785,0.653,all P < 0.05).The value of LVEF obtained by echocardiography VLA was associated with it obtained by MRI (r =0.690,P < 0.05).The value of SV obtained by echocardiography HLA and echocardiography SA were associated with those obtained by MRI (r =0.734,0.701,all P < 0.05).Conclusion There are differences in accuracy and reliability using echocardiography and MRI when measuring dilated cardiomyopathy heart function,which must be treated differently.
10.Statistical Analysis of Publications in Chinese Journal of Medical Imaging from 2013 to 2015
Liyan LONG ; Lei ZHANG ; Shuo CHEN ; Liuquan CHENG ; Yujuan DENG
Chinese Journal of Medical Imaging 2016;24(12):957-960
Purpose A systematic analysis of the articles published in the Chinese Journal of Medical Imaging from year 2013 to 2015 was performed to investigate its features of acceptance and publication for future decision making.Methods The printed journal and retrieved data from the Chinese Hospital Knowledge Database was analyzed using biometrical index,including the number of the papers,subspecialties,publication types,medical imaging modalities,MeSH frequency,citation and download.Results From year 2013 to 2015,there were 770 papers published,21.4 articles per issue and 0.267 articles per page in average.The top three subspecialty were abdominal imaging,chest imaging and reviews/comments,accounting for 17.27%,9.61%,9.48%,respectively.The top three modalities were CT,ultrasound and MRI,accounting for 39.61%,38.31%,29.87%,respectively.The original research papers were 584,accounting for 75.84%.The frequent MeSH subjects were differential diagnosis,angiography,pathology,computer-assisted image processing and contrast agents.Totally,there were 2395 citations and averagely 3.11 citation for each paper.The top citation was 36.There were 71317 downloads and 92.62 for each paper in average,the top download was 499.Conclusions The publications and its density per page increased annually from 2013 to 2015.The subspecialty were fully covered,the papers focus on original researches and clinical applications.The publication theme could follow the tendency of the imaging technology and had good and steady effects in the field.

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