In 2024, the American College of Gastroenterology (ACG) and the American Society for Gastrointestinal Endoscopy (ASGE) comprehensively updated the quality indicators for colonoscopy. This update aims to enhance the quality of colonoscopy, thereby more effectively reducing the inci-dence of colorectal cancer. The update contents include optimization of traditional quality control indicators, as well as the introduction of new assessment standards, such as the detection rate of sessile serrated lesions. Key priority indicators, including adenoma detection rate and adequate bowel preparation rate, have been further refined and quantified to ensure their operability in clinical practice. The updated indicator system emphasizes a balanced focus on both outcome evaluation based on long-term clinical data and process quality assessments, further underscoring the scientific nature and standardization of these quality control measures. The authors review the quality control indicators of the updated version and provide a systematic analysis of the clinical significance and specific operational guidelines for priority indicators. Additionally, they explore the critical role of these quality control measures in improving colonoscopy quality and reducing the risk of missed diagnoses. The aim of this review is to promote the further refinement and implementation of quality control standards, thereby providing stronger support for early prevention and treatment of colorectal cancer.

In 2024, the American College of Gastroenterology (ACG) and the American Society for Gastrointestinal Endoscopy (ASGE) comprehensively updated the quality indicators for colonoscopy. This update aims to enhance the quality of colonoscopy, thereby more effectively reducing the inci-dence of colorectal cancer. The update contents include optimization of traditional quality control indicators, as well as the introduction of new assessment standards, such as the detection rate of sessile serrated lesions. Key priority indicators, including adenoma detection rate and adequate bowel preparation rate, have been further refined and quantified to ensure their operability in clinical practice. The updated indicator system emphasizes a balanced focus on both outcome evaluation based on long-term clinical data and process quality assessments, further underscoring the scientific nature and standardization of these quality control measures. The authors review the quality control indicators of the updated version and provide a systematic analysis of the clinical significance and specific operational guidelines for priority indicators. Additionally, they explore the critical role of these quality control measures in improving colonoscopy quality and reducing the risk of missed diagnoses. The aim of this review is to promote the further refinement and implementation of quality control standards, thereby providing stronger support for early prevention and treatment of colorectal cancer.

A double burden of overweight/obesity and malnutrition during childhood is a major concern in China. Dietary intakes in this critical period affect children's physical and cognitive development, and also have health consequences in later life. Therefore, establishing healthy eating habits that will endure is crucial for children. Nutrition education is an effective way in improving nutrition knowledge and attitudes, and healthy eating behaviors. Diverse forms of nutrition improvement programs that targeting children, family, teachers, and school settings have been conducted in many developed countries. However, due to the differences of genetic background, household environment as well as dietary patterns between Chinese children and children from other countries, the existing nutrition education programs for children abroad might not be appropriate for children in China. Thus, nutrition education programs that consider Chinese nutrition-related policies and food supply as well as the local educational resources are required for Chinese children. This review summarized nutrition-related policies and legislations in China and developed countries. A series of evidence-based nutrition education programs that combined educational strategies and environmental supports conducted in the Southwest China Childhood Nutrition and Growth Study were presented. These programs can serve as example models for adopting nutrition interventions to improve nutrition and health status of children in different regions of China.

Objective To investigate the association of tumor necrosis factor-ot (TNF-α) gene promoter polymorphisms with generalized pustular psoriasis.Methods Totally,91 patients of Han nationality with generalized pustular psoriasis (generalized pustular psoriasis group) and 102 health checkup examinees (healthy control group) were enrolled into this study.PCR and direct sequencing were performed to analyze the-238,-308 and-857 polymorphic sites of the TNF-α promoter.Results The frequency of the A allele at TNF-α-238 site was significantly higher in the generalized pustular psoriasis group than in the healthy control group (P =0.003,OR =4.819,95％ CI:1.581-14.694),so was the frequency of GA/AA genotype (P =0.006,OR =4.455,95％ CI:1.410-14.077).However,no significant differences were observed in the frequencies of G/A alleles (P =0.794) and GG/GA/AA genotypes (P =0.786) at TNF-o-308 site,or in the frequencies of C/T alleles (P =0.474) and CC/CT/TT genotypes (P =0.453) at TNF-α-857 site,between the generalized pustular psoriasis group and healthy control group.Conclusion TNF-α-238G ＞ A polymorphisms may be associated with the occur-rence of generalized pustular psoriasis.