Objective To explore the effectiveness and feasibility of internet-based structured group cognitive behavior therapy (I-GCBT) in patients with mild depressive disorder.Methods In this randomized controlled trial,based on a random number table which was generated from spss20.0,96 patients with mild depressive disorder were randomized to I-GCBT(n=64) and face-to-face group cognitive behavior therapy(GCBT,n=32).I-GCBT and GCBT patients were assessed by HAMD17,HAMA,Global Assessment of Functioning Scale,GAF and 16 Items Quick Inventory of Depressive Symptomatology-Self Report,QIDS-SR16 at baseline,4th week,8th week and 12th week.The differences between I-GCBT and GCBT were analyzed by repetitive measure analysis of variance and chi-square test.Results (1)There was no significant difference between I-GCBT and GCBT on demographics,duration of past depression history,baseline of HAMD17,GAF and QIDS-SR16,but a significantly higher HAMA seen in GCBT (t=-2.08,P=0.04).(2) The interaction of times and groups was significant in GAF (F=4.09,P＜0.01) but not in HAMD17,HAMA and QIDS-SR16 (F=0.69,P＞0.05;F=0.95,P＞0.05;F=0.64,P＞0.05).In all measurement scales,Time main effects were significant (HAMD17∶ F=32.81,P＜0.01;HAMA∶ F=20.86,P＜0.01;GAF∶ F=105.98,P＜0.01;QIDS-SR16∶ F=25.27,P＜0.01).The symptoms remission rate of the overall patients was 62％ (43/69) after 12 weeks treatment,lower in I-GCBT (57％,25/44) and higher in GCBT (72％,18/25).There was no significant difference between two groups (x2=1.57,P=0.21).(3) The overall dropout rate was 26％ during the 12-weeks treatment specifically 29％(15/51) in I-GCBT and 20％(6/30) in GCBT without significant difference in-between (x2=0.87,P=0.35).97％(58/60) patients rated the treatment as acceptable (I-GCBT∶ 97％(35/36),GCBT∶ 96％ (23/24)),and the difference of acceptability between two groups was not significant (x2=0.09,P=0.78).Conclusion The effectiveness and feasibility of I-GCBT are comparable to GCBT for mild depressive disorder.And the treatment adherence of I-GCBT seems good.

Objective To explore the effectiveness and feasibility of internet-based structured group cognitive behavior therapy (I-GCBT) in patients with mild depressive disorder.Methods In this randomized controlled trial,based on a random number table which was generated from spss20.0,96 patients with mild depressive disorder were randomized to I-GCBT(n=64) and face-to-face group cognitive behavior therapy(GCBT,n=32).I-GCBT and GCBT patients were assessed by HAMD17,HAMA,Global Assessment of Functioning Scale,GAF and 16 Items Quick Inventory of Depressive Symptomatology-Self Report,QIDS-SR16 at baseline,4th week,8th week and 12th week.The differences between I-GCBT and GCBT were analyzed by repetitive measure analysis of variance and chi-square test.Results (1)There was no significant difference between I-GCBT and GCBT on demographics,duration of past depression history,baseline of HAMD17,GAF and QIDS-SR16,but a significantly higher HAMA seen in GCBT (t=-2.08,P=0.04).(2) The interaction of times and groups was significant in GAF (F=4.09,P＜0.01) but not in HAMD17,HAMA and QIDS-SR16 (F=0.69,P＞0.05;F=0.95,P＞0.05;F=0.64,P＞0.05).In all measurement scales,Time main effects were significant (HAMD17∶ F=32.81,P＜0.01;HAMA∶ F=20.86,P＜0.01;GAF∶ F=105.98,P＜0.01;QIDS-SR16∶ F=25.27,P＜0.01).The symptoms remission rate of the overall patients was 62％ (43/69) after 12 weeks treatment,lower in I-GCBT (57％,25/44) and higher in GCBT (72％,18/25).There was no significant difference between two groups (x2=1.57,P=0.21).(3) The overall dropout rate was 26％ during the 12-weeks treatment specifically 29％(15/51) in I-GCBT and 20％(6/30) in GCBT without significant difference in-between (x2=0.87,P=0.35).97％(58/60) patients rated the treatment as acceptable (I-GCBT∶ 97％(35/36),GCBT∶ 96％ (23/24)),and the difference of acceptability between two groups was not significant (x2=0.09,P=0.78).Conclusion The effectiveness and feasibility of I-GCBT are comparable to GCBT for mild depressive disorder.And the treatment adherence of I-GCBT seems good.