1.The Implementation Dilemmas and Optimization Suggestions of the Hospital Financial System from the Perspective of Policy Coordination
Linnan XUE ; Xinrui YU ; Wenqian LI ; Wanli GUO
Chinese Health Economics 2025;44(11):99-103
Objective:It aims to further optimize the Hospital Financial System to better adapt to the high-quality development of public hospitals.Methods:The implementation difficulties of the current Hospital Financial System is analyzed to explore its optimization logic from the perspective of policy synergy.Results:The optimization of the Hospital Financial System should reflect the achievements and directions of government accounting reform,scientifically reflect the laws of fund movement and policy management requirements,and further implement the spirit of financial and accounting supervision.Conclusion:It is suggested to comprehensively optimize the Hospital Financial System from the basic principles,main tasks,and other clauses,so as to better regulate the operation of funds,improve the level of hospital financial management,and help public hospitals achieve high-quality and sustainable development.
2.Determination of Volatile Organic Compounds in Medical Molecular Sieve Oxygen Concentrators by Thermal Desorption-Gas Chromatography-Mass Spectrometry.
Danmei ZHAO ; Bin XUE ; Congkai WEI ; Haihua KANG ; Yuanli HUANG ; Linnan KE
Chinese Journal of Medical Instrumentation 2025;49(5):585-590
A method for determining volatile organic compounds (VOCs) emitted from medical molecular sieve oxygen concentrators was developed using thermal desorption-gas chromatography-mass spectrometry (TD-GC-MS). The oxygen concentrator gas was sampled at a flow rate of 0.5 L/min through a branched sampling system onto Tenax GR/carbopack B adsorption tubes. The adsorbed compounds were desorbed and introduced using a programmed temperature vaporization inlet system, followed by chromatographic separation on an SH-I-624Sil MS column. Four VOCs (BHT-Q, PTBP, BHT-quinol, and EHB) were detected in the medical oxygen concentrator using this method. Calibration curves for these compounds exhibited excellent linearity ( R 2>0.99) within the range of 3~100 ng. With a sampling volume of 20 L, the detection limit of the four VOCs ranged from 0.003 9 to 0.022 2 μg/m 3. Spike recovery rates for the four VOCs were between 95% and 115%, with relative standard deviations (RSDs) below 5% ( n=6). The method is simple, rapid, highly sensitive, and accurate, making it suitable for VOCs detection in medical molecular sieve oxygen concentrators.
Volatile Organic Compounds/analysis*
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Gas Chromatography-Mass Spectrometry/methods*
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Oxygen
3.The Implementation Dilemmas and Optimization Suggestions of the Hospital Financial System from the Perspective of Policy Coordination
Linnan XUE ; Xinrui YU ; Wenqian LI ; Wanli GUO
Chinese Health Economics 2025;44(11):99-103
Objective:It aims to further optimize the Hospital Financial System to better adapt to the high-quality development of public hospitals.Methods:The implementation difficulties of the current Hospital Financial System is analyzed to explore its optimization logic from the perspective of policy synergy.Results:The optimization of the Hospital Financial System should reflect the achievements and directions of government accounting reform,scientifically reflect the laws of fund movement and policy management requirements,and further implement the spirit of financial and accounting supervision.Conclusion:It is suggested to comprehensively optimize the Hospital Financial System from the basic principles,main tasks,and other clauses,so as to better regulate the operation of funds,improve the level of hospital financial management,and help public hospitals achieve high-quality and sustainable development.
4.Molecular biologicalstudy of DEL in RhD-negative blood donors, Dalian
Ni WANG ; Shihang ZHOU ; Linnan SHAO ; Yuexin XIA ; Wenxu XUE ; Weijian YU
Chinese Journal of Blood Transfusion 2021;34(11):1193-1196
【Objective】 To study the frequency, Rh phenotypes and molecular & biological background of D-elute (Del) phenotype in RhD-negative blood donors in Dalian. 【Methods】 A total of 355 serologically RhD-negative samples between November, 2018 and October, 2019 in Dalian Blood Center were collected, and tested for RhC, c, E, e phenotypes using monoclonal antibodies and anti-D adsorption/elution test. DNA was extracted by magnetic bead selection. RHD 1227G>A mutation was detected by melting curve analysis. All RHD exons were sequenced by Sanger sequencing. 【Results】 Among 355 serologically RhD-negative blood donors, 55 (15.5%) were identified as Del and the remaining 300 cases (84.5%) were true RhD negative. Ccee (45/55, 81.8%) was the predominant Rh phenotype among 55 Del cases while ccee (210/300, 70.0%) was the most prevalent Rh phenotypes in 300 true RhD negative cases. In 55 Del cases, 51 (92.7%) had RHD 1227G>A mutation, and the other 4 cases(7.3%) had mutations in other sites. 【Conclusion】 The frequency of Del was 15.5% in serologically RhD-negative blood donors in Dalian, with Ccee being the most prevalent Rh phenotype and RHD 1227G>A the most common gene mutation.
5.Determination of fructose and glucose in assisted reproductive culture medium by high performance liquid chromatography-differential refractive index detector
Xue SUN ; Yuanli HUANG ; Linnan KE
Chinese Journal of Tissue Engineering Research 2014;(30):4873-4877
BACKGROUND:Nowadays, the component content of assisted reproductive culture medium and their test methods are unclear in the quality standards. We need to establish the test methods to fil this vacancy, so as to control the quality of assisted reproductive culture medium effectively. OBJECTIVE:To establish an evaluation method for determination of fructose and glucose in assisted reproductive culture medium, thereby based on which to establish the quality standards. METHODS:High performance liquid chromatography-differential refractive index detector was adopted and Rezex RCM-Monosaccharide Ca2+(8%) (300.0 mm×7.8 mm) column was used. The mobile phase was ultrapure water at the flow rate of 0.6 mL/min and the temperature of 80 ℃. RESULTS AND CONCLUSION:Resolution of the peaks of glucose and fructose was 3.2. The linear ranges of glucose and fructose were 30.1-502 mg/L (r=0.999 8) and 102-408 mg/L (r=0.999 8), respectively. The relative standard deviation of reproducibility test was 0.17%and 0.40%, respectively. The relative standard deviation of stability test was 0.22%and 0.73%, respectively. The glucose group and fructose group average recovery rates were 1.22%and 1.38%, respectively. The methodology of High performance liquid chromatography-differential refractive index detector accorded with the requirements. The glucose contents of samples 1 and 2 were 96.7 mg/L and 99.6 mg/L, respectively. The fructose contents of samples 1 and 2 were 208.5 mg/L and 197.4 mg/L, respectively. A reliable, simple, and accurate method was provided for the quality control of assisted reproductive culture medium, which fil s the domestic vacancy in the quality standards for assisted reproductive culture medium.

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