Objective:To investigate the epidemiological status of knee joint tuberculous arthritis in 52 patients and to identify risk factors for recurrence after treatment.Methods:A retrospective analysis was conducted involving 52 patients with knee joint tuberculous arthritis who received treatment at Shaanxi Provincial Tuberculosis Prevention and Control Hospital from January 2018 to June 2023. Patients concurrently diagnosed with knee joint tuberculous arthritis were identified from the hospital's records, and their clinical data were collected. Logistic regression analysis was performed to determine the risk factors associated with recurrence of knee joint tuberculous arthritis.Results:The incidence of knee joint tuberculous arthritis is higher in males than in females, with the most affected age group being 40-60 years old. The most common form of the disease is total knee joint tuberculosis. The positive rate of Mycobacterium tuberculosis culture is 100%, indicating high diagnostic value. Logistic regression analysis results show that the following are independent risk factors for recurrence of knee joint tuberculous arthritis: age > 45 years ( OR = 3.080, 95% CI: 1.445-6.564, P = 0.004), body mass index < 18.5 kg/m2 ( OR = 6.062, 95% CI: 1.621-22.671, P = 0.007), smoking ( OR = 2.649, 95% CI: 1.032-6.799, P = 0.043), diabetes ( OR = 3.629, 95% CI: 1.799-7.321, P = 0.007), duration of tuberculosis symptoms > 6 months ( OR = 5.507, 95% CI: 1.210-25.055, P = 0.027), non-compliance with anti-tuberculosis medication ( OR = 3.152, 95% CI: 1.149-8.649, P = 0.026), elevated erythrocyte sedimentation rate ( OR = 3.297, 95% CI: 1.223-8.889, P = 0.018), and elevated C-reactive protein ( OR = 2.519, 95% CI: 1.025-6.194, P = 0.044). Conclusions:Knee joint tuberculous arthritis is more prevalent in males, with the most affected age group being 40-60 years old. Clinically, a comprehensive diagnosis that includes clinical evaluation, imaging, and bacterial culture is necessary. Lesion excision surgery can result in a good prognosis. Independent risk factors for the recurrence of knee joint tuberculous arthritis include age > 45 years, body mass index < 18.5 kg/m2, smoking, diabetes, duration of tuberculosis symptoms > 6 months, non-compliance with anti-tuberculosis medication, elevated serum erythrocyte sedimentation rate, and elevated C-reactive protein.

Objective:To investigate the epidemiological status of knee joint tuberculous arthritis in 52 patients and to identify risk factors for recurrence after treatment.Methods:A retrospective analysis was conducted involving 52 patients with knee joint tuberculous arthritis who received treatment at Shaanxi Provincial Tuberculosis Prevention and Control Hospital from January 2018 to June 2023. Patients concurrently diagnosed with knee joint tuberculous arthritis were identified from the hospital's records, and their clinical data were collected. Logistic regression analysis was performed to determine the risk factors associated with recurrence of knee joint tuberculous arthritis.Results:The incidence of knee joint tuberculous arthritis is higher in males than in females, with the most affected age group being 40-60 years old. The most common form of the disease is total knee joint tuberculosis. The positive rate of Mycobacterium tuberculosis culture is 100%, indicating high diagnostic value. Logistic regression analysis results show that the following are independent risk factors for recurrence of knee joint tuberculous arthritis: age > 45 years ( OR = 3.080, 95% CI: 1.445-6.564, P = 0.004), body mass index < 18.5 kg/m2 ( OR = 6.062, 95% CI: 1.621-22.671, P = 0.007), smoking ( OR = 2.649, 95% CI: 1.032-6.799, P = 0.043), diabetes ( OR = 3.629, 95% CI: 1.799-7.321, P = 0.007), duration of tuberculosis symptoms > 6 months ( OR = 5.507, 95% CI: 1.210-25.055, P = 0.027), non-compliance with anti-tuberculosis medication ( OR = 3.152, 95% CI: 1.149-8.649, P = 0.026), elevated erythrocyte sedimentation rate ( OR = 3.297, 95% CI: 1.223-8.889, P = 0.018), and elevated C-reactive protein ( OR = 2.519, 95% CI: 1.025-6.194, P = 0.044). Conclusions:Knee joint tuberculous arthritis is more prevalent in males, with the most affected age group being 40-60 years old. Clinically, a comprehensive diagnosis that includes clinical evaluation, imaging, and bacterial culture is necessary. Lesion excision surgery can result in a good prognosis. Independent risk factors for the recurrence of knee joint tuberculous arthritis include age > 45 years, body mass index < 18.5 kg/m2, smoking, diabetes, duration of tuberculosis symptoms > 6 months, non-compliance with anti-tuberculosis medication, elevated serum erythrocyte sedimentation rate, and elevated C-reactive protein.

Objective: This study aimed to analyze the influencing factors of cerebral hemodynamics index (CVHI) and provide evidence on early warning of stroke in ethnic minorities (Tujia, Buyi, Dong, Miao). Methods: From April 2017 to April 2019, ethnic minorities were examined in the Health Management Center of the Affiliated Hospital of Guizhou Medical University to determine the nationality, age, sex, medical history (such as hypertension, hyperlipidemia, and diabetes) and menstruation in women; measure physiological indexes, such as height and weight, and biochemical indexes, such as blood glucose, blood lipid, and serum uric acid levels; and conduct CVHI and bilateral arm ankle pulse wave conduction velocity (baPWV) detection. The CVHI integral was calculated and divided into normal CVHI group (≥75 points) and abnormal CVHI group (<75 points) to describe the characteristics of population distribution and analyze the related influencing factors of CVHI. Results: A total of 1 236 individuals belonging to ethnic minorities [age, 52.0±9.0 years; 575 men (46.52%) and 661 women (53.48%)]were included in the study. In ethnic minorities, 35.11% had abnormal CVHI. There was no significant difference in abnormal CVHI among ethnic groups, from highest to lowest, in Buyi nationality (38.22%), Miao nationality (37.93%), Dong nationality (32.70%), and Tujia nationality (32.36%). Minority women, menopausal patients, and patients with history of hypertension, diabetes, and hyperlipidemia more frequently had abnormal CVHI than men and non-menopausal and normal women (43.57%, 47.48%, and 57.66%, 76.19%, and 54.00% vs. 25.39%, 39.51%, and 32.30% 35.31%, and 34.74%, P<0.05). The mean BMI, systolic blood pressure (SBP), diastolic blood pressure (DBP), and FPG and TG levels, baPWV in the abnormal CVHI group were higher than those in the normal CVHI group, and height was lower the abnormal CVHI group than that in the normal group (P<0.05). The correlation analysis showed that height (r=0.309) was positively correlated with CVHI integral and SBP (r=-0.239), DBP (r=-0.189), and baPWV (r=-0.184) were negatively correlated with CVHI integral (P<0.001). The higher the height, the higher the CVHI and the lower the risk of stroke, and the higher the SBP, DBP, and baPWV, the lower the CVHI score and the higher the risk of stroke. The factor logistic regression analysis showed that old age (OR, 1.992; 95%CI, 1.405-2.825); female sex (OR, 2.240; 95%CI, 1.750-2.866); history of hypertension (OR, 3.363; 95%CI, 1.665-6.791), menopause (OR, 1.384; 95%CI, 1.016-1.885), and high SBP (OR, 1.031; 95%CI, 1.019-1.044), BMI (OR, 1.091; 95%CI, 1.048-1.135), FPG level (OR, 1.169; 95%CI, 1.017-1.344), and baPWV (OR, 1.002; 95%CI, 1.001-1.002) were risk factors for abnormal CVHI, and increased height (OR, 0.936; 95%CI 0.920-0.952) was the protective factor. Conclusion Individuals in ethnic minorities frequently have abnormal CVHI. The main risk factors of CVHI are the elderly, female, history of hypertension, menopause, systolic blood pressure, body mass index, fasting blood glucose and baPWV. It is necessary to strengthen the health management of ethnic minority gathering places, controling body weight, regularly monitoring of blood pressure and blood glucose and lipid levels, and examing cerebral vascular hemodynamics.