1.Visualization Analysis of Research Hotspots and Development Trends of Immune Cells in Radiotherapy for Rectal Cancer
Lingzhen JIANG ; Feiyu QIN ; Yuna LI ; Yan QIN ; Junhui TANG ; Liang MING ; Xiaowei QI ; Zhaohui HUANG ; Yuan YIN
Cancer Research on Prevention and Treatment 2026;53(7):523-533
Objective To analyze the overall characteristics, research hotspots, and development trends of immune cell-related studies in radiotherapy for rectal cancer. Methods A systematic search was conducted by using Web of Science Core Collection to retrieve articles related to radiation therapy and immune cells in rectal cancer published from 1991 to 2024. Advanced bibliometric tools, such as VOSviewer and CiteSpace, were utilized to facilitate analysis and describe publication trends, geographic contributions, institutional affiliations, journal prominence, author collaboration, and prominent keywords. Results The annual number of relevant publications has increased steadily, showing remarkable growth over the past five years. Studies focusing on adaptive immune cells (T and B cells) account for the largest proportion of works and form the most extensive collaboration networks, reflecting the central role of T cell–mediated antitumor immunity in radiotherapy. Meanwhile, innate immune cells, including myeloid-derived suppressor cells, macrophages, monocytes, and neutrophils, are increasingly investigated for their regulatory roles in shaping the tumor immune microenvironment and influencing therapeutic responses. Among countries, China and the United States have contributed the highest number of publications and demonstrated strong academic influence. While several stable research groups have been formed, intergroup collaboration remains limited. Keyword analysis revealed that radiotherapy-induced immune modulation, tumor immune microenvironment remodeling, and treatment response have emerged as major research hotspots. Conclusion Research on immune cells in rectal cancer radiotherapy has progressed rapidly in recent years. The emphasis of this field has gradually shifted from single-treatment approaches to mechanistic studies investigating the interaction between radiotherapy and the tumor immune microenvironment. The field still demonstrates considerable potential for future research and clinical translational applications.
2.Experience of KONG Yaoqi in Treating Tic Disorder with Scalp Acupuncture Triotherapy
Qinqin SHI ; Lingzhen JIANG ; Weibo MAO
Journal of Zhejiang Chinese Medical University 2025;49(5):606-610
[Objective]To investigate the clinical characteristics and efficacy of Chief KONG Yaoqi's scalp acupuncture triotherapy in the treatment of tic disorder.[Methods]This study analyzed and summarized the theoretical foundation and operational techniques of Chief KONG's scalp acupuncture triotherapy through collecting and analyzing the typical cases and relevant literature.Additionally,a supporting case is provided.[Results]Tic disorder is a common neuropsychiatric disease.Chief KONG believes that the location of tic disorder is in the brain and heart,emphasizing treatment based on the spirit.Scalp acupuncture can stimulate specific regions of the head,thereby enhancing neurological function.Body acupuncture is used to treat the cause and mechanism with tonification and purgation,while acupoint application is used to enhance the body's resistance and nourish the primordial energy.The patient in this case was caused by wind movement due to deficiency,Chief KONG used scalp acupuncture to calm the mind and spirit to stop the tics,body acupuncture to suppress wind and stop convulsions to control the movements,indirect moxibustion and acupoint application to tonify the kidney and spleen.The therapeutic effect was definite.[Conclusion]Chief KONG's combined therapy of scalp acupuncture emphasizes treating children's tic disorder based on the spirit and focuses on tonifying the liver,spleen and kidney.His clinical experience is worthy of promotion and application in clinical practice.
3.Experience of KONG Yaoqi in Treating Tic Disorder with Scalp Acupuncture Triotherapy
Qinqin SHI ; Lingzhen JIANG ; Weibo MAO
Journal of Zhejiang Chinese Medical University 2025;49(5):606-610
[Objective]To investigate the clinical characteristics and efficacy of Chief KONG Yaoqi's scalp acupuncture triotherapy in the treatment of tic disorder.[Methods]This study analyzed and summarized the theoretical foundation and operational techniques of Chief KONG's scalp acupuncture triotherapy through collecting and analyzing the typical cases and relevant literature.Additionally,a supporting case is provided.[Results]Tic disorder is a common neuropsychiatric disease.Chief KONG believes that the location of tic disorder is in the brain and heart,emphasizing treatment based on the spirit.Scalp acupuncture can stimulate specific regions of the head,thereby enhancing neurological function.Body acupuncture is used to treat the cause and mechanism with tonification and purgation,while acupoint application is used to enhance the body's resistance and nourish the primordial energy.The patient in this case was caused by wind movement due to deficiency,Chief KONG used scalp acupuncture to calm the mind and spirit to stop the tics,body acupuncture to suppress wind and stop convulsions to control the movements,indirect moxibustion and acupoint application to tonify the kidney and spleen.The therapeutic effect was definite.[Conclusion]Chief KONG's combined therapy of scalp acupuncture emphasizes treating children's tic disorder based on the spirit and focuses on tonifying the liver,spleen and kidney.His clinical experience is worthy of promotion and application in clinical practice.
4."The Collecting and Studying of Wang Fu's ""YiLing CuanYao TanYuan"""
Journal of Zhejiang Chinese Medical University 2015;(8):636-638,642
Objective]Collecting and studying Wang Fu and his book YiLing CuanYao TanYuan systematically. [Method]Literature research on Wang Fu's life and the versions ofYiLing CuanYao TanYuan, reviewing his concept of study and academic thoughts. [Result]Confucian Wang Fu wrote more than 30 manuscripts, his medical masterpiece“YiLing CuanYao TanYuan, existing versions of two Qing printed editions and one Qing transcript, guided by medical source, centered on traditional Chinese medicine and prescription, accounted for human disease, made a comprehensive and profound elaboration on the basic theory of TCM.The recipes and traditional Chinese medicine of this book have clinical significance . [Conclusion]The collecting and studying have important literature value. These are worthy of our future generations to inherit and carry forward.

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