1.Clinical effect of bone melon extract combined with loronoxicam in elderly patients after total hip arthroplasty
Kaili ZHANG ; Xin FAN ; Lingtong SUN
China Pharmacist 2024;27(8):1320-1326
Objective To investigate the clinical effect of bone melon extract(BME)combined with lornoxicam(LN)in elderly patients after total hip arthroplasty.Methods Elderly patients with femoral neck fracture attending the Department of Orthopedics of Xixi Hospital in Hangzhou City from January 2020 to June 2023 were retrospectively selected as study subjects.According to different postoperative treatment programs,they were divided into the BME group(LN combined with BME treatment)and the LN group(LN treatment).The visual analog scores(VAS)and Oswestry dysfunction index questionnaire(ODI)scores of patients in the two groups preoperatively and postoperatively,the changes of inflammatory factors[C-reactive protein(CRP),interleukin-6(IL-6),and tumor necrosis factor-α(TNF-α)]before surgery and 4 weeks after surgery,and the clinical efficacy of patients in the two groups preoperatively and at 6 months postoperatively,the hip joint function(Harris score),daily living ability[Barthel index(BI)]and quality of life[Mos36-Item Short Form Health Survey(SF-36)]were compared.Results A total of 100 patients were included in the study,with 56 in the BME group and 44 in the LN group.Before treatment,the differences in VAS scores,ODI scores,inflammatory factors,Harris scores,BI and SF-36 between the two groups were not statistically significant(P>0.05).After treatment,VAS scores,ODI scores,CRP,IL-6 and TNF-αdecreased significantly in both groups compared with those before treatment(P<0.05);and these indicators in the BME group were lower than those in the LN group(P<0.05).In terms of therapeutic efficacy,the therapeutic efficiency of the BME group was significantly higher than that of the LN group(P<0.05).Harris scores,BI and SF-36 significantly increased in both groups(P<0.05),and these in the BME group were greater than those in the LN group(P<0.05).Conclusion Compared with LN treatment alone,BME combined with LN can promote rapid recovery in elderly patients after total hip arthroplasty.
2.Anatomical research of positional relationship between protective channel and sural nerve during Achilles tendon repair using channel assisted minimally invasive repair technique.
Zhonghe WANG ; Wenhao CAO ; Hongzhe QI ; Lingtong KONG ; Haoyu LIU ; Chen CHEN ; Lianhua LI ; Lijun SUN ; Hua CHEN
Chinese Journal of Reparative and Reconstructive Surgery 2024;38(11):1325-1329
OBJECTIVE:
To evaluate the positional relationship between protective channel and sural nerve while treating acute Achilles tendon rupture with channel assisted minimally invasive repair (CAMIR) technique based on anatomical observations of cadaver specimens.
METHODS:
Twelve adult cadaveric lower limb specimens (6 left, 6 right) were utilized. A CAMIR device was implanted at a distance of 4 cm from the proximal end of the specimen to the Achilles tendon insertion. The skin was incised along the tendon's medial side, the sural nerve was dissected, and the positional relationship with the protective channel was observed. The distance from the sural nerve-Achilles tendon intersection to the calcaneal insertion, the vertical distance between protective channel and the calcaneal insertion, and the horizontal distance between the sural nerve and protective channel were measured by using vernier caliper.
RESULTS:
Anatomical examination demonstrated a variable positional relationship between the sural nerve and protective channel, with the sural nerve positioned above (8 specimens) or below (4 specimens) the protective channel. The distance from the sural nerve-Achilles tendon intersection to the calcaneal insertion was (105.67±14.94) mm, the vertical distance between protective channel and the calcaneal insertion was (93.20±9.57) mm, and the horizontal distance between the sural nerve and protective channel was (0.31±0.14) mm.
CONCLUSION
The use of CAMIR technique for the treatment of acute Achilles tendon rupture can effectively avoid iatrogenic injury to the sural nerve.
Humans
;
Achilles Tendon/injuries*
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Sural Nerve/anatomy & histology*
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Cadaver
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Minimally Invasive Surgical Procedures/methods*
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Tendon Injuries/surgery*
;
Rupture/surgery*
;
Adult
;
Male
;
Calcaneus/injuries*
;
Female
;
Plastic Surgery Procedures/methods*

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