Objective:To analyze the risk factors for postoperative shoulder joint dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury.Methods:Eighty-three patients with postoperative shoulder dysfunction with surgical neck fractures of the humerus combined with rotator cuff injury who received treatment at Zhuji Central Hospital from January 2019 to December 2022 were included in the observation group. Additionally, 80 patients with surgical neck fractures of the humerus combined with rotator cuff injury who concurrently received treatment at the same hospital but did not suffer from shoulder dysfunction after surgery were included in the control group. The general data of the two groups were analyzed. The Pearson test was used to assess the correlation between age, the presence of osteoporosis, the surgical reduction method, the Neer classification of the shoulder joint, and the occurrence of shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury after surgery. Multivariate logistic regression analysis was performed to analyze the risk factors for postoperative shoulder dysfunction in these patients. Results:The proportion of patients over 70 years old, the proportion of patients with osteoporosis, the proportion of patients with Neer type III fractures and above, and the proportion of patients undergoing conventional reduction in the observation group were 48.19% (40/83), 60.24% (50/83), 36.14% (30/83), and 60.24% (50/83), respectively. These proportions were significantly higher than those in the control group [18.75% (15/80), 41.25% (33/80), 18.75% (15/80), and 43.75% (35/80), χ2 = 21.37, 5.87, 7.06, 4.44, P < 0.001, 0.015, 0.029, 0.035]. Pearson's correlation test revealed that age, combined osteoporosis, fracture Neer classification, and routine reduction were positively correlated with the postoperative development of shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury ( r = 0.812, 0.796, 0.823, 0.814, all P < 0.05). Multivariate logistic regression analysis results showed that age, osteoporosis, fracture Neer classification, and conventional reduction were risk factors for postoperative shoulder dysfunction in these patients ( OR = 3.504, 3.823, 3.607, 4.059, all P < 0.05). Conclusions:Age, osteoporosis, fracture Neer classification, and conventional reduction are risk factors for postoperative shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury. A systematic preoperative evaluation and adherence to rehabilitation exercises after surgery may help reduce the incidence of shoulder joint dysfunction.

Objective:To analyze the risk factors for postoperative shoulder joint dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury.Methods:Eighty-three patients with postoperative shoulder dysfunction with surgical neck fractures of the humerus combined with rotator cuff injury who received treatment at Zhuji Central Hospital from January 2019 to December 2022 were included in the observation group. Additionally, 80 patients with surgical neck fractures of the humerus combined with rotator cuff injury who concurrently received treatment at the same hospital but did not suffer from shoulder dysfunction after surgery were included in the control group. The general data of the two groups were analyzed. The Pearson test was used to assess the correlation between age, the presence of osteoporosis, the surgical reduction method, the Neer classification of the shoulder joint, and the occurrence of shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury after surgery. Multivariate logistic regression analysis was performed to analyze the risk factors for postoperative shoulder dysfunction in these patients. Results:The proportion of patients over 70 years old, the proportion of patients with osteoporosis, the proportion of patients with Neer type III fractures and above, and the proportion of patients undergoing conventional reduction in the observation group were 48.19% (40/83), 60.24% (50/83), 36.14% (30/83), and 60.24% (50/83), respectively. These proportions were significantly higher than those in the control group [18.75% (15/80), 41.25% (33/80), 18.75% (15/80), and 43.75% (35/80), χ2 = 21.37, 5.87, 7.06, 4.44, P < 0.001, 0.015, 0.029, 0.035]. Pearson's correlation test revealed that age, combined osteoporosis, fracture Neer classification, and routine reduction were positively correlated with the postoperative development of shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury ( r = 0.812, 0.796, 0.823, 0.814, all P < 0.05). Multivariate logistic regression analysis results showed that age, osteoporosis, fracture Neer classification, and conventional reduction were risk factors for postoperative shoulder dysfunction in these patients ( OR = 3.504, 3.823, 3.607, 4.059, all P < 0.05). Conclusions:Age, osteoporosis, fracture Neer classification, and conventional reduction are risk factors for postoperative shoulder dysfunction in patients with surgical neck fractures of the humerus combined with rotator cuff injury. A systematic preoperative evaluation and adherence to rehabilitation exercises after surgery may help reduce the incidence of shoulder joint dysfunction.

Objective To study the effect of immunotherapy on expression of CD14+mHLA-DR and the serum levels of immunoglobulin (IgG, IgA and IgM) in patients with severe pneumonia, so as to discuss the feasibility of immunotherapy for severe pneumonia. Methods From January 2012 to April 2014, 120 cases of patients with severe pneumonia treated in the intensive care unit (ICU) and pneumonia department were collected. Patients were randomly divided into control group (60 cases) and treatment group (60 cases). The control group was administrated with conventional therapy , and the treatment group was given thymosin α1 for immune treatment for 7 days. The mHLA-DR expression and the level of IgG , IgA and IgM of the two groups before and after the treatment were compared. Results After thymosin α1 treatment, mHLA-DR expression rate was elevated , and the serum levels of IgG , IgA and IgM were elevated in the treatment group , and the difference was statistically significant (P < 0.05). While there was no statistically significant difference betweenthe above indicators before and after treatment (P > 0.05). Conclusion After immune treatment with the use of thymosin α1 , immunologic suppression can be prevented , and cellar immune function of severe pneumonia patients can be improved.