Objective To explore the influencing factors of physical activity(PA)in overweight and obese children from the individual,family and environment levels.Methods Using a stratified cluster random sampling method,315 children[mean age:9.57±1.45 years;201 boys(63.8%)and 114 girls(36.2%)]were selected from two classes of every grade of one public elementary school in the four main urban districts of Shijiazhuang.Hierarchical linear regression models were employed to ana-lyze the influence of 20 factors on individual,family and environment levels on PA among them.Re-sults Children's age(β=-0.02),sex(βmale=0.12),sedentary time(β=-0.07),ball skills(β=0.12),perceived motor competence(β=0.18),primary caregiver's PA(β=0.17),parental PA support(β=0.10)and home/neighborhood PA environment(β=0.40)were significant factors of their moderate-to-vigorous physical activities(P<0.05).For light physical activity(LPA)and total PA,only sedentary time(βLPA=-0.57,βtotal=-0.52),parental support for children's PA(βLPA=0.15,βtotal=0.16),and home/neighborhood PA environment(βLPA=0.17,βtotal=0.15)were significant predictors(Pall<0.05).Conclusion The influencing factors of PA among overweight and obese children are complex and multidimensional.Elements at the individual,family and environment levels all play significant roles.Therefore,future interventions and policies aimed at promoting PA in this population should take these multifaceted de-terminants into consideration.

Objective To explore the influencing factors of physical activity(PA)in overweight and obese children from the individual,family and environment levels.Methods Using a stratified cluster random sampling method,315 children[mean age:9.57±1.45 years;201 boys(63.8%)and 114 girls(36.2%)]were selected from two classes of every grade of one public elementary school in the four main urban districts of Shijiazhuang.Hierarchical linear regression models were employed to ana-lyze the influence of 20 factors on individual,family and environment levels on PA among them.Re-sults Children's age(β=-0.02),sex(βmale=0.12),sedentary time(β=-0.07),ball skills(β=0.12),perceived motor competence(β=0.18),primary caregiver's PA(β=0.17),parental PA support(β=0.10)and home/neighborhood PA environment(β=0.40)were significant factors of their moderate-to-vigorous physical activities(P<0.05).For light physical activity(LPA)and total PA,only sedentary time(βLPA=-0.57,βtotal=-0.52),parental support for children's PA(βLPA=0.15,βtotal=0.16),and home/neighborhood PA environment(βLPA=0.17,βtotal=0.15)were significant predictors(Pall<0.05).Conclusion The influencing factors of PA among overweight and obese children are complex and multidimensional.Elements at the individual,family and environment levels all play significant roles.Therefore,future interventions and policies aimed at promoting PA in this population should take these multifaceted de-terminants into consideration.

The different fate of liposomes among species has been discovered and mentioned in many studies, but the underlying mechanisms have not been explored. In the present work, we concentrated on the in vivo fate of PEGylated liposomes (sLip) in three commonly used species (mice, rats, and dogs). It was exhibited that the accelerated blood clearance (ABC) phenomenon and hypersensitivity in large animals (beagle dogs) were much more significant than that in rodents. We demonstrated that anti-PEG IgM (partially) and complement (mostly) determined the elimination of sLip and linked the distinct interspecies performances with the diverse complement capacity among species. Based on the data from animals and clinical patients, it was revealed that the fate of sLip in large animals was closer to that in humans, for the sufficient complement capacity could expose the potential adverse reactions caused by anti-PEG antibodies. Our results suggested that the distinctive interspecies performances of sLip were highly related to the physiological variabilities among species, which should not be overlooked in the innovation and translation of nanomedicines.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.

Traditional Chinese medicine is an important part of Chinese traditional culture and has played an increasingly important role in the field of health care in recent years.Shandong Province,as a province with large resources of traditional Chinese medicine,has the natural advantages and deep foundation to develop traditional Chinese medicine health care industry.Based on Strengths,Weaknesses,Opportunities & Threats(SWOT)analysis,the advantages,disadvantages,opportunities and challenges of the development of traditional Chinese medicine health care industry in Shandong Province were deeply analyzed.SWOT matrix model was constructed to put forward targeted countermeasures and suggestions,in order to provide theoretical support and practical guidance for the healthy development of traditional Chinese medicine health care industry in Shandong Province.