A detection model based on Gramian angular field(GAF)and parallel KConvNeXt network is proposed for accurately detecting the abnormal conditions caused by sample needle blockage in the sampling system during the sampling,thus improving the testing accuracy and detection efficiency of automated biochemical analyzers.GAF-based method is employed to transform the time series of one-dimensional pressure signals into two-dimensional image representations.Subsequently,an improved attention mechanism integrated with a parallel dual-channel KConvNeXt network is used to classify the pressure signals,and achieves a final classification accuracy of 94.58%.The experimental results show that the proposed method can effectively capture the key characteristics of the pressure signals,offering an efficient solution for the anomalous pressure detection in biochemical analyzer sampling system and exhibiting important practical significance.

A detection model based on Gramian angular field(GAF)and parallel KConvNeXt network is proposed for accurately detecting the abnormal conditions caused by sample needle blockage in the sampling system during the sampling,thus improving the testing accuracy and detection efficiency of automated biochemical analyzers.GAF-based method is employed to transform the time series of one-dimensional pressure signals into two-dimensional image representations.Subsequently,an improved attention mechanism integrated with a parallel dual-channel KConvNeXt network is used to classify the pressure signals,and achieves a final classification accuracy of 94.58%.The experimental results show that the proposed method can effectively capture the key characteristics of the pressure signals,offering an efficient solution for the anomalous pressure detection in biochemical analyzer sampling system and exhibiting important practical significance.

Objective To understand the status of soil?transmitted nematode infections in Xiding Township,Menghai Coun?ty,Yunnan Province,so as to provide the reference for formulating the strategy of soil?transmitted nematodosis control. Meth?ods Soil?transmitted nematode eggs in feces were detected by the Kato?Katz method,and the eggs of Enterobius vermicularis were detected by the cellophane tape method in children. The soil samples were collected from vegetable ,fruit and other crop fields of 15 residents randomly to detect hookworm. Results The stool samples from 1 002 residents were examined and the soil?transmitted nematode infection rate was 20.06%(201/1 002). The infection rates of hookworm,Ascaris lumbricoides and Trichu?ris trichura were 18.96%(190 cases),1.70%(17 cases)and 0.90%(9 cases)respectively. The percentages of people with light infection of hookworm,A. lumbricoides and T. trichura were 97.37%(185/190),88.24%(15/17)and 100%(9/9)respec?tively. No infection of E. vermicularis was found. Fifteen soil samples were tested,and no hookworm was found in the soil. Con?clusion The infection rate of soil?transmitted nematode in Xiding Township,Menghai County is high,but the infectiosity is light. The control and monitoring of soil?transmitted nematodosis should be strengthened in this area.

To look for new genes from human brain, get a fragment was obtained using adaptor primer and 3' anchor polymerase chain reaction (PCR) with the human adult whole brain cDNA as template. The fragment was cloned into T easy vector and automatically sequenced with 310 Genetic Analyzer. Later the whole length cDNA of this novel gene was got with the method of 3'rapid amplification of cDNA end (RACE). The whole length of cDNA of this novel gene is 2 024 bp. Chromsome location is at 14q11.2 including 16 extrons and 15 introns. After scanning the sequence against GenBank it is proved that the sequence is a new one. ORF analysis showed that there is a complete coding region in it,it can interprate a protein containing 357 amino acid residules. ProDom analysis result showed that there is an acyl carrier protein (ACP) like domain in it. The gene was banked into GenBank. Then, a pare of primers were designed and were used to amplify the coding region and cloned into pGEX-4T1 expressing vector to express it in E. coli . The Dot blotting and Northern blot showed that this novel gene is highly expressed in the normal adult human brain.