The clinical practice guidelines for Chinese patent medicines （CPM） provide reference for the selection of national drug catalogs， the formulation of prescription collections in medical institutions， and the clinical use of CPM， constituting an important part of traditional Chinese medicine （TCM） guidelines. As a crucial part of Chinese drug supply guarantee system， CPM plays an important role in the treatment， prevention， and healthcare of many disease categories， whereas the application of CPM has problems of misuse and even abuse. To standardize the application of CPM， a research team at Zhejiang Chinese Medical University developed the Reporting Items for Practice Guidelines in Healthcare for Chinese Patent Medicines （RIGHT for CPM） based on the RIGHT checklist framework. The RIGHT for CPM checklist gathers key information from published CPM guidelines， existing TCM reporting checklists， and the RIGHT checklist and its extensions to form an initial pool of reporting items. Seventeen experts from different disciplines were invited to conduct two rounds of Delphi surveys， and the final checklist was reviewed and approved for publication by 18 leading experts in TCM research and guideline reporting from China and abroad. The RIGHT for CPM checklist adds 16 sub-items and revises 2 sub-items on the basis of the RIGHT checklist， highlighting the characteristics of CPM guideline reporting. It considers CPM selection and inclusion criteria， policy access， indications and symptoms， drug combination instructions， drug use in special populations， precautions， and recommendations of Western medical physicians， among others. This can further improve the quality and transparency of CPM guideline reporting， promote standardized reporting of CPM guidelines， and facilitate the rational clinical use of CPM. This article interprets the development process of the RIGHT for CPM checklist and the items that highlight the characteristics of CPM guidelines， with a view to promoting the application of the RIGHT for CPM checklist.

[Objective]To explore data on traditional Chinese medicine formulas for the treatment of rheumatoid arthritis(RA),analyze medication patterns and provide ideas for the clinical staging treatment of RA.[Methods]Using the China Patent Publication Platform of the State Intellectual Property Office,the patent data of traditional Chinese medicine compounds for RA published from the establishment date of the database to November 2023 were systematically collected,and the frequency of drug application,nature and taste,and efficacy of the included traditional Chinese medicine formulas were analyzed.Correlation analysis,cluster analysis and latent structure analysis were used to explore the core prescriptions of traditional Chinese medicine in the treatment of different stages of RA.[Results]Two hundred and ninety-nine traditional Chinese medicine formulas were included,including 537 traditional Chinese medicines,with a total frequency of 3 739 times.The nature and flavor of the medicines are primarily categorized as warm,neutral,and cold.The channel tropism of the medicines is generally classified into the liver,spleen,kidney,and heart meridians.High-frequency traditional Chinese medicine can be classified into six primary categories and nine secondary subcategories.The high-frequency drug combinations used in association analysis included"Huangqi → Guizhi"and"Ruxiang → Myrrh".The cluster analysis of 58 high-frequency traditional Chinese medicines with frequency≥20 times was carried out,and the results showed that 6 clusters were formed.Among them,wind and dampness obstruction and deficiency of Qi and blood belonged to the pre-RA state,damp-heat obstruction belonged to the acute phase,cold dampness obstruction belonged to the chronic phase,phlegm stasis obstruction and liver and kidney deficiency belonged to the remission phase.[Conclusion]Traditional Chinese medicine formulas therapy for RA often starts from the three major causes of deficiency,evil and blood stasis,by using drugs that dispel wind and dampness,promote blood circulation and remove blood stasis,and nourish deficiency.It follows the principle of"treating the same disease differently"and emphasizes staged treatment,Which providing a certain reference for clinical treatment.

[Objective]To explore data on traditional Chinese medicine formulas for the treatment of rheumatoid arthritis(RA),analyze medication patterns and provide ideas for the clinical staging treatment of RA.[Methods]Using the China Patent Publication Platform of the State Intellectual Property Office,the patent data of traditional Chinese medicine compounds for RA published from the establishment date of the database to November 2023 were systematically collected,and the frequency of drug application,nature and taste,and efficacy of the included traditional Chinese medicine formulas were analyzed.Correlation analysis,cluster analysis and latent structure analysis were used to explore the core prescriptions of traditional Chinese medicine in the treatment of different stages of RA.[Results]Two hundred and ninety-nine traditional Chinese medicine formulas were included,including 537 traditional Chinese medicines,with a total frequency of 3 739 times.The nature and flavor of the medicines are primarily categorized as warm,neutral,and cold.The channel tropism of the medicines is generally classified into the liver,spleen,kidney,and heart meridians.High-frequency traditional Chinese medicine can be classified into six primary categories and nine secondary subcategories.The high-frequency drug combinations used in association analysis included"Huangqi → Guizhi"and"Ruxiang → Myrrh".The cluster analysis of 58 high-frequency traditional Chinese medicines with frequency≥20 times was carried out,and the results showed that 6 clusters were formed.Among them,wind and dampness obstruction and deficiency of Qi and blood belonged to the pre-RA state,damp-heat obstruction belonged to the acute phase,cold dampness obstruction belonged to the chronic phase,phlegm stasis obstruction and liver and kidney deficiency belonged to the remission phase.[Conclusion]Traditional Chinese medicine formulas therapy for RA often starts from the three major causes of deficiency,evil and blood stasis,by using drugs that dispel wind and dampness,promote blood circulation and remove blood stasis,and nourish deficiency.It follows the principle of"treating the same disease differently"and emphasizes staged treatment,Which providing a certain reference for clinical treatment.

Pre-rheumatoid arthritis （Pre-RA） is the asymptomatic state of rheumatoid arthritis （RA）， and its progression showed complexity， dynamics and significant individual differences. The dynamic prediction model is valuable in identifying individual risks and taking timely preventive and control measures. It is believed that applying the dynamic prediction model to traditional Chinese medicine （TCM） clinical studies of Pre-RA is expected to predict the critical state of Pre-RA to RA， reveal the evolution of Pre-RA， reflect the external authenticity of the TCM clinical studies， and complement the clinical efficacy evaluation method. Accordingly， it is envisioned to construct a dynamic prediction model for Pre-RA progression based on TCM clinical trial data through the dynamic prediction model algorithm， and to apply long-term follow-up cohort data for external validation， thereby providing a basis for scientific warning and clinical decision-making on the evolution of Pre-RA.